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Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem‐Progenitor Cells

Stem cells (Dayton, Ohio), 2016-06, Vol.34 (6), p.1651-1663

2016

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The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs

Cell reports (Cambridge), 2016-11, Vol.17 (8), p.2087-2100

2016

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Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

Experimental hematology, 2003-05, Vol.31 (5), p.398-405

2003

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STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells

JAK-STAT, 2012-01, Vol.1 (1), p.13-25

2012

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Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability

Nature communications, 2022-04, Vol.13 (1), p.2013-2013, Article 2013

2022

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Putative Autophagy Protein VMP1 Amplifies Protective Autophagy Under Stress Conditions in AML Cells

Blood, 2017-12, Vol.130, p.3918-3918

2017

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Convergence of hypoxia and TGFβ pathways on cell cycle regulation in human hematopoietic stem/progenitor cells

PloS one, 2014-03, Vol.9 (3), p.e93494-e93494

2014

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Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia

Cell death & disease, 2017-07, Vol.8 (7), p.e2927-e2927

2017

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Full Spectrum 40-Parameter Single-Tube Flow Cytometry Analysis for Longitudinal Immunophenotyping and Tracing of Clonal Heterogeneity in AML

Blood, 2022-11, Vol.140 (Supplement 1), p.9140-9141

2022

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The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia

Nature communications, 2022-03, Vol.13 (1), p.1105-1105, Article 1105

2022

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Presence of mutant p53 increases stem cell frequency and is associated with reduced binding to classic TP53 binding sites in cell lines and primary AMLs

Experimental hematology, 2022-06, Vol.110, p.39-46

2022

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The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia

Blood advances, 2024-01, Vol.8 (1), p.56-69

2024

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Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels

Molecular and Cellular Biology, 2008-11, Vol.28 (21), p.6668-6680

2008

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Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

Cell reports (Cambridge), 2019-01, Vol.26 (4), p.1059-1069.e6

2019

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Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

PloS one, 2016-04, Vol.11 (4), p.e0153226-e0153226

2016

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Proteolytic degradation of Smad4 in extracts of AML blasts

Leukemia research, 2002-12, Vol.26 (12), p.1105-1111

2002

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Identification of HIF2α as an important STAT5 target gene in human hematopoietic stem cells

Blood, 2011-03, Vol.117 (12), p.3320-3330

2011

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Convergence Of Hypoxia and TGFβ Pathways On Cell Cycle Regulation In Human Hematopoietic Stem/Progenitor Cells

Blood, 2013-11, Vol.122 (21), p.3694-3694

2013

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STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

Blood, 2007-10, Vol.110 (8), p.2880-2888

2007

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ATG5 and ATG7 Fulfill Essential and Non-Redundant Roles in Human Hematopoietic Stem/Progenitor Cells

Blood, 2014-12, Vol.124 (21), p.4316-4316

2014

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Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation

Blood, 2010-06, Vol.115 (22), p.4367-4376

2010

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Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses

PloS one, 2009-11, Vol.4 (11), p.e7989-e7989

2009

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Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem‐Progenitor Cells

The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells

Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability

Putative Autophagy Protein VMP1 Amplifies Protective Autophagy Under Stress Conditions in AML Cells

Convergence of hypoxia and TGFβ pathways on cell cycle regulation in human hematopoietic stem/progenitor cells

Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia

Dietary methionine starvation impairs acute myeloid leukemia progression

Full Spectrum 40-Parameter Single-Tube Flow Cytometry Analysis for Longitudinal Immunophenotyping and Tracing of Clonal Heterogeneity in AML

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia

Presence of mutant p53 increases stem cell frequency and is associated with reduced binding to classic TP53 binding sites in cell lines and primary AMLs

The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia

Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

Proteolytic degradation of Smad4 in extracts of AML blasts

Identification of HIF2α as an important STAT5 target gene in human hematopoietic stem cells

Convergence Of Hypoxia and TGFβ Pathways On Cell Cycle Regulation In Human Hematopoietic Stem/Progenitor Cells

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

ATG5 and ATG7 Fulfill Essential and Non-Redundant Roles in Human Hematopoietic Stem/Progenitor Cells

Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia

Combined HAT/EZH2 modulation leads to cancer-selective cell death

Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses

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