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Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

Nature reviews. Rheumatology, 2020-09, Vol.16 (9), p.496-513

2020

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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

Cell reports (Cambridge), 2020-04, Vol.31 (1), p.107492, Article 107492

2020

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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Nature communications, 2015-02, Vol.6 (1), p.6282-6282, Article 6282

2015

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NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

The Journal of experimental medicine, 2020-05, Vol.217 (5)

2020

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Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

Nature communications, 2022-01, Vol.13 (1), p.166-166, Article 166

2022

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Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway

The Journal of immunology (1950), 2018-03, Vol.200 (5), p.1802-1816

2018

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TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

The Journal of immunology (1950), 2019-06, Vol.202 (11), p.3151-3160

2019

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GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

The Journal of experimental medicine, 2016-09, Vol.213 (10), p.1983-1998

2016

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Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface

Journal of allergy and clinical immunology, 2018-12, Vol.142 (6), p.1956-1967.e6

2018

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Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

European heart journal, 2018-06, Vol.39 (23), p.2158-2167

2018

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Post-infectious group A streptococcal autoimmune syndromes and the heart

Autoimmunity reviews, 2015-08, Vol.14 (8), p.710-725

2015

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Different cross-presentation pathways in steady-state and inflammatory dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (48), p.20377-20381

2009

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Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis

Annals of the rheumatic diseases, 2012-12, Vol.71 (12), p.1980-1983

2012

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Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4392-4402

2016

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Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

Arthritis & rheumatology (Hoboken, N.J.), 2023-02, Vol.75 (2), p.305-317

2023

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Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation

International journal of molecular sciences, 2021-05, Vol.22 (9), p.4910

2021

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GM-CSF as a therapeutic target in inflammatory diseases

Molecular immunology, 2013-12, Vol.56 (4), p.675-682

2013

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Therapeutic Effects of a TANK‐Binding Kinase 1 Inhibitor in Germinal Center–Driven Collagen‐Induced Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2019-01, Vol.71 (1), p.50-62

2019

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Limbic

Annals of internal medicine, 2022-11, Vol.175 (11), p.1621

Wicks, Ian P.

2022

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Natural killer cells in inflammatory autoimmune diseases

Clinical & translational immunology, 2021, Vol.10 (2), p.e1250-n/a

2021

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G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

Nature reviews. Rheumatology, 2009-10, Vol.5 (10), p.554-559

2009

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Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

Journal of extracellular vesicles, 2018-12, Vol.7 (1), p.1490145-n/a

2018

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Interleukin-6 in rheumatoid arthritis - from the laboratory to the bedside

Current pharmaceutical design, 2015-01, Vol.21 (17), p.2187-2197

2015

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Targeting GM-CSF in inflammatory diseases

Nature reviews. Rheumatology, 2016-01, Vol.12 (1), p.37-48

2016

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Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies

Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway

TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Post-infectious group A streptococcal autoimmune syndromes and the heart

Different cross-presentation pathways in steady-state and inflammatory dendritic cells

Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease

Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation

GM-CSF as a therapeutic target in inflammatory diseases

Therapeutic Effects of a TANK‐Binding Kinase 1 Inhibitor in Germinal Center–Driven Collagen‐Induced Arthritis

Limbic

Natural killer cells in inflammatory autoimmune diseases

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

Interleukin-6 in rheumatoid arthritis - from the laboratory to the bedside

Targeting GM-CSF in inflammatory diseases

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