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Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Nature structural & molecular biology, 2003-01, Vol.10 (1), p.19-25

2003

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Consistent manufacturing and quality control of a highly complex recombinant polyclonal antibody product for human therapeutic use

Biotechnology and bioengineering, 2011-09, Vol.108 (9), p.2171-2181

2011

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Production of target-specific recombinant human polyclonal antibodies in mammalian cells

Biotechnology and bioengineering, 2006-06, Vol.94 (2), p.396-405

2006

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Alanine Scanning Mutagenesis of Insulin

The Journal of biological chemistry, 1997-05, Vol.272 (20), p.12978-12983

1997

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Discovery and Structure−Activity Relationship of the First Non-Peptide Competitive Human Glucagon Receptor Antagonists

Journal of medicinal chemistry, 1998-12, Vol.41 (26), p.5150-5157

1998

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Changing the insulin receptor to possess insulin-like growth factor I ligand specificity

Biochemistry (Easton), 1990-08, Vol.29 (32), p.7363-7366

1990

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Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes

FEBS letters, 1996-07, Vol.390 (1), p.109-112

1996

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Specificity of Insulin and Insulin-like Growth Factor I Receptors Investigated using Chimeric Mini-Receptors

The Journal of biological chemistry, 1999-12, Vol.274 (52), p.37351-37356

1999

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Identification of a calcium binding site in the protease domain of human blood coagulation factor VII: evidence for its role in factor VII - tissue factor interaction

Biochemistry (Easton), 1993-01, Vol.32 (1), p.114-119

1993

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Expression and Characterization of a 70-kDa Fragment of the Insulin Receptor That Binds Insulin

The Journal of biological chemistry, 1998-07, Vol.273 (28), p.17780-17786

1998

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Specificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunit

The Journal of biological chemistry, 1999-12, Vol.274 (52), p.37351-37356

1999

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Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

Biochemical journal, 1996-04, Vol.315 ( Pt 1) (1), p.271-279

1996

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Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor

The Journal of biological chemistry, 1998-07, Vol.273 (28), p.17780

1998

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Selective Down-regulation of the Insulin Receptor Signal by Protein-tyrosine Phosphatases α and

The Journal of biological chemistry, 1995-09, Vol.270 (39), p.23126-23131

1995

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Human plasma and recombinant factor VII. Characterization of O-glycosylations at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine

The Journal of biological chemistry, 1991-06, Vol.266 (17), p.11051-11057

1991

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The Ligand Specificities of the Insulin Receptor and the Insulin-Like Growth Factor I Receptor Reside in Different Regions of a Common Binding Site

Proceedings of the National Academy of Sciences - PNAS, 1991-05, Vol.88 (10), p.4404-4408

1991

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Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions

The Journal of biological chemistry, 1990-10, Vol.265 (28), p.16786-16793

1990

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Immobilized insulin for high capacity affinity chromatography of insulin receptors

The Journal of biological chemistry, 1991-10, Vol.266 (28), p.18814-18818

1991

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Identification of determinants that confer ligand specificity on the insulin receptor

The Journal of biological chemistry, 1992-07, Vol.267 (19), p.13681-13686

1992

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Chimeric receptors indicate that phenylalanine 39 is a major contributor to insulin specificity of the insulin receptor

The Journal of biological chemistry, 1994-12, Vol.269 (52), p.32942-32946

1994

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Localization of Specific Amino Acids Contributing to Insulin Specificity of the Insulin Receptor

Annals of the New York Academy of Sciences, 1995-09, Vol.766 (1), p.466-468

1995

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P-18: Increased insulin affinity of the IGF-I receptor requires a nonpolar aromatic amino acid at position #32

Experimental and clinical endocrinology & diabetes, 1996, Vol.104 (S 02), p.83-83

1996

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Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors

The Journal of biological chemistry, 1993-02, Vol.268 (5), p.3044-3047

1993

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Selective Down-regulation of the Insulin Receptor Signal by Protein-tyrosine Phosphatases Î± and Ïµ

The Journal of biological chemistry, 1995-09, Vol.270 (39), p.23126

1995

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P-12: Expression, characterization and purification of soluble insulin receptor-immunoglobulin chimeras that retain high-affinity insulin binding

Experimental and clinical endocrinology & diabetes, 1996, Vol.104 (S 02), p.77-78

1996

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Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Consistent manufacturing and quality control of a highly complex recombinant polyclonal antibody product for human therapeutic use

Production of target-specific recombinant human polyclonal antibodies in mammalian cells

Alanine Scanning Mutagenesis of Insulin

Discovery and Structure−Activity Relationship of the First Non-Peptide Competitive Human Glucagon Receptor Antagonists

Changing the insulin receptor to possess insulin-like growth factor I ligand specificity

Characterization of recombinant human HBP/CAP37/azurocidin, a pleiotropic mediator of inflammation-enhancing LPS-induced cytokine release from monocytes

Specificity of Insulin and Insulin-like Growth Factor I Receptors Investigated using Chimeric Mini-Receptors

Identification of a calcium binding site in the protease domain of human blood coagulation factor VII: evidence for its role in factor VII - tissue factor interaction

Expression and Characterization of a 70-kDa Fragment of the Insulin Receptor That Binds Insulin

Specificity of insulin and insulin-like growth factor I receptors investigated using chimeric mini-receptors. Role of C-terminal of receptor alpha subunit

Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor

Selective Down-regulation of the Insulin Receptor Signal by Protein-tyrosine Phosphatases α and

Human plasma and recombinant factor VII. Characterization of O-glycosylations at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine

The Ligand Specificities of the Insulin Receptor and the Insulin-Like Growth Factor I Receptor Reside in Different Regions of a Common Binding Site

Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions

Immobilized insulin for high capacity affinity chromatography of insulin receptors

Identification of determinants that confer ligand specificity on the insulin receptor

Chimeric receptors indicate that phenylalanine 39 is a major contributor to insulin specificity of the insulin receptor

Localization of Specific Amino Acids Contributing to Insulin Specificity of the Insulin Receptor

P-18: Increased insulin affinity of the IGF-I receptor requires a nonpolar aromatic amino acid at position #32

Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors

Selective Down-regulation of the Insulin Receptor Signal by Protein-tyrosine Phosphatases Î± and Ïµ

P-12: Expression, characterization and purification of soluble insulin receptor-immunoglobulin chimeras that retain high-affinity insulin binding

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