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The emerging roles of AhR in physiology and immunity

Biochemical pharmacology, 2013-09, Vol.86 (5), p.561-570

2013

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The mammalian basic helix–loop–helix/PAS family of transcriptional regulators

International Journal of Biochemistry and Cell Biology, 2004-02, Vol.36 (2), p.189-204

2004

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Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

Science (American Association for the Advancement of Science), 2002-02, Vol.295 (5556), p.858-861

2002

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Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.3037-3041

2013

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Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

Scientific reports, 2021-03, Vol.11 (1), p.6602-6602, Article 6602

2021

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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3368-3373

2008

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NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease

PloS one, 2011-07, Vol.6 (7), p.e21907-e21907

2011

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Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation

Nucleic acids research, 2013-06, Vol.41 (11), p.5626-5638

2013

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A Constitutively Active Dioxin/Aryl Hydrocarbon Receptor Induces Stomach Tumors

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (15), p.9990-9995

2002

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NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways

Biomolecules (Basel, Switzerland), 2023-10, Vol.13 (10), p.1545

2023

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The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors

FEBS letters, 2007-07, Vol.581 (19), p.3616-3625

2007

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Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

PloS one, 2014-01, Vol.9 (1), p.e85768-e85768

2014

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Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling

Molecular pharmacology, 2012-12, Vol.82 (6), p.1082-1093

2012

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bHLH-PAS proteins in cancer

Nature reviews. Cancer, 2013-12, Vol.13 (12), p.827-841

2013

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Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties

Biophysical reports, 2023-03, Vol.3 (1), p.100100, Article 100100

2023

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Inducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression

PloS one, 2015-03, Vol.10 (3), p.e0116373-e0116373

2015

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Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain

Biomolecules (Basel, Switzerland), 2020-09, Vol.10 (9), p.1314

2020

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Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2

Biochemical journal, 2014-08, Vol.461 (3), p.403-412

2014

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HIF has Biff – Crosstalk between HIF1a and the family of bHLH/PAS proteins

Experimental cell research, 2017-07, Vol.356 (2), p.141-145

2017

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Contribution of the Per/Arnt/Sim (PAS) Domains to DNA Binding by the Basic Helix-Loop-Helix PAS Transcriptional Regulators

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.5353-5362

2004

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Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

Molecular metabolism (Germany), 2017-11, Vol.6 (11), p.1419-1428

2017

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The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

Nucleic acids research, 2008-06, Vol.36 (11), p.3716-3727

2008

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Defining the Role for XAP2 in Stabilization of the Dioxin Receptor

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.35878-35888

2003

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Substrate Requirements of the Oxygen-sensing Asparaginyl Hydroxylase Factor-inhibiting Hypoxia-inducible Factor

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.14391-14397

2004

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Genes & development, 2002-06, Vol.16 (12), p.1466-1471

2002

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The emerging roles of AhR in physiology and immunity

The mammalian basic helix–loop–helix/PAS family of transcriptional regulators

Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features

Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease

Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation

A Constitutively Active Dioxin/Aryl Hydrocarbon Receptor Induces Stomach Tumors

NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways

The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function

Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling

bHLH-PAS proteins in cancer

Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties

Inducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression

Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2

HIF has Biff – Crosstalk between HIF1a and the family of bHLH/PAS proteins

Contribution of the Per/Arnt/Sim (PAS) Domains to DNA Binding by the Basic Helix-Loop-Helix PAS Transcriptional Regulators

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

Defining the Role for XAP2 in Stabilization of the Dioxin Receptor

Substrate Requirements of the Oxygen-sensing Asparaginyl Hydroxylase Factor-inhibiting Hypoxia-inducible Factor

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

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