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Revealing disease-associated pathways by network integration of untargeted metabolomics

Nature methods, 2016-09, Vol.13 (9), p.770

2016

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Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

Nature communications, 2020-06, Vol.11 (1), p.2760-2760, Article 2760

2020

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Peak learning of mass spectrometry imaging data using artificial neural networks

Nature communications, 2021-09, Vol.12 (1), p.5544-5544, Article 5544

2021

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High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors

Cancer research (Chicago, Ill.), 2021-05, Vol.81 (9), p.2495-2509

2021

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Oncogenic EGFR signaling networks in glioma

Science signaling, 2009-09, Vol.2 (87), p.re6

2009

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Multiple Reaction Monitoring for Robust Quantitative Proteomic Analysis of Cellular Signaling Networks

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (14), p.5860-5865

2007

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Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

Cancer research (Chicago, Ill.), 2020-03, Vol.80 (6), p.1258-1267

2020

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Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I

eLife, 2023-04, Vol.12

2023

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Early signaling dynamics of the epidermal growth factor receptor

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (11), p.3114-3119

2016

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Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (31), p.12867-12872

2007

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SirT1 is required in the male germ cell for differentiation and fecundity in mice

Development (Cambridge), 2014-09, Vol.141 (18), p.3495-3504

2014

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Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3

Science signaling, 2011-10, Vol.4 (196), p.rs11

2011

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Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

Molecular and Cellular Biology, 2009-07, Vol.29 (14), p.3845-3852

2009

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Patient-specific signaling signatures predict optimal therapeutic combinations for triple negative breast cancer

Molecular cancer, 2024-01, Vol.23 (1), p.17-17, Article 17

2024

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High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network

Molecular systems biology, 2019-08, Vol.15 (8), p.e8849-n/a

2019

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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Molecular systems biology, 2020-12, Vol.16 (12), p.e9819-n/a

2020

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Hepatic Dysfunction Caused by Consumption of a High-Fat Diet

Cell reports (Cambridge), 2017-12, Vol.21 (11), p.3317-3328

2017

Volltextzugriff (PDF)

Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules

Molecular & cellular proteomics, 2005-09, Vol.4 (9), p.1240-1250

2005

Volltextzugriff (PDF)

Phosphoproteomic approaches to elucidate cellular signaling networks

Current opinion in biotechnology, 2006-08, Vol.17 (4), p.406-414

2006

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Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (30), p.13252-13257

2010

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Molecular Characterization of EGFR and EGFRvIII Signaling Networks in Human Glioblastoma Tumor Xenografts

Molecular & cellular proteomics, 2012-12, Vol.11 (12), p.1724-1740

2012

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Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation

PloS one, 2015-05, Vol.10 (5), p.e0126242-e0126242

2015

Volltextzugriff (PDF)

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

Nature biotechnology, 2002-03, Vol.20 (3), p.301-305

2002

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Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

eLife, 2020-09, Vol.9

2020

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Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance

Biochemical Society transactions, 2014-08, Vol.42 (4), p.758

2014

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Revealing disease-associated pathways by network integration of untargeted metabolomics

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition

Peak learning of mass spectrometry imaging data using artificial neural networks

High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors

Oncogenic EGFR signaling networks in glioma

Multiple Reaction Monitoring for Robust Quantitative Proteomic Analysis of Cellular Signaling Networks

Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I

Early signaling dynamics of the epidermal growth factor receptor

Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma

SirT1 is required in the male germ cell for differentiation and fecundity in mice

Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3

Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

Patient-specific signaling signatures predict optimal therapeutic combinations for triple negative breast cancer

High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet

Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules

Phosphoproteomic approaches to elucidate cellular signaling networks

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling

Molecular Characterization of EGFR and EGFRvIII Signaling Networks in Human Glioblastoma Tumor Xenografts

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation

Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity

Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance

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