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Cancer pharmacogenomics: strategies and challenges

Nature reviews. Genetics, 2013-01, Vol.14 (1), p.23-34

2013

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Integrating predicted transcriptome from multiple tissues improves association detection

PLoS genetics, 2019-01, Vol.15 (1), p.e1007889-e1007889

2019

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A gene-based association method for mapping traits using reference transcriptome data

Nature genetics, 2015-09, Vol.47 (9), p.1091-1098

2015

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Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues

PLoS genetics, 2016-11, Vol.12 (11), p.e1006423

2016

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Genetic architecture of gene expression traits across diverse populations

PLoS genetics, 2018-08, Vol.14 (8), p.e1007586-e1007586

2018

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Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer

Journal of clinical oncology, 2016-08, Vol.34 (23), p.2712-2720

2016

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Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries

Genome Biology, 2022-01, Vol.23 (1), p.23-23, Article 23

2022

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Genetic regulatory variation in populations informs transcriptome analysis in rare disease

Science (American Association for the Advancement of Science), 2019-10, Vol.366 (6463), p.351-356

2019

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Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells

PloS one, 2015-02, Vol.10 (2), p.e0118020

2015

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Genetically regulated gene expression underlies lipid traits in Hispanic cohorts

PloS one, 2019-08, Vol.14 (8), p.e0220827

2019

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Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

Clinical cancer research, 2017-10, Vol.23 (19), p.5757-5768

2017

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Comparing local ancestry inference models in populations of two- and three-way admixture

PeerJ (San Francisco, CA), 2020-10, Vol.8, p.e10090-e10090, Article e10090

2020

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Multi-ethnic transcriptome-wide association study of prostate cancer

PloS one, 2020-09, Vol.15 (9), p.e0236209

2020

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Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia

PeerJ (San Francisco, CA), 2019-09, Vol.7, p.e7778-e7778, Article e7778

2019

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Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate

iScience, 2020-12, Vol.23 (12), p.101850-101850, Article 101850

2020

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Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

Clinical cancer research, 2020-12, Vol.26 (24), p.6550-6558

2020

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Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila

BMC genomics, 2019-01, Vol.20 (1), p.14-14, Article 14

2019

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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy

Clinical cancer research, 2015-10, Vol.21 (19), p.4337-4346

2015

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Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels

PeerJ (San Francisco, CA), 2018-01, Vol.6, p.e4314-e4314, Article e4314

2018

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Transcriptome prediction performance across machine learning models and diverse ancestries

HGG advances, 2021-04, Vol.2 (2), p.100019, Article 100019

2021

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Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging

PLoS genetics, 2009-10, Vol.5 (10), p.e1000685-e1000685

2009

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EPS8 inhibition increases cisplatin sensitivity in lung cancer cells

PloS one, 2013-12, Vol.8 (12), p.e82220

2013

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Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations

HGG advances, 2023-10, Vol.4 (4), p.100216-100216, Article 100216

2023

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Identification of novel germline polymorphisms governing capecitabine sensitivity

Cancer, 2012-08, Vol.118 (16), p.4063-4073

2012

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Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations

Human molecular genetics, 2021-04, Vol.30 (3-4), p.305-317

2021

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Cancer pharmacogenomics: strategies and challenges

Integrating predicted transcriptome from multiple tissues improves association detection

A gene-based association method for mapping traits using reference transcriptome data

Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues

Genetic architecture of gene expression traits across diverse populations

Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries

Genetic regulatory variation in populations informs transcriptome analysis in rare disease

Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells

Genetically regulated gene expression underlies lipid traits in Hispanic cohorts

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

Comparing local ancestry inference models in populations of two- and three-way admixture

Multi-ethnic transcriptome-wide association study of prostate cancer

Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia

Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate

Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila

Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels

Transcriptome prediction performance across machine learning models and diverse ancestries

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells

Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations

Identification of novel germline polymorphisms governing capecitabine sensitivity

Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations

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