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Methods for applying accurate digital PCR analysis on low copy DNA samples

PloS one, 2013-03, Vol.8 (3), p.e58177-e58177

2013

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The Digital MIQE Guidelines Update: Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020

Clinical chemistry (Baltimore, Md.), 2020-08, Vol.66 (8), p.1012-1029

Huggett, Jim F

2020

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Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

Nucleic acids research, 2012-06, Vol.40 (11), p.e82-e82

2012

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Digital PCR as a novel technology and its potential implications for molecular diagnostics

Clinical chemistry (Baltimore, Md.), 2013-12, Vol.59 (12), p.1691-1693

2013

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Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification

Analytical and bioanalytical chemistry, 2014, Vol.406 (26), p.6499-6512

2014

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Fundamentals of multiplexing with digital PCR

Biomolecular detection and quantification, 2016-12, Vol.10, p.15-23

2016

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RT-qPCR and RT-Digital PCR: A Comparison of Different Platforms for the Evaluation of Residual Disease in Chronic Myeloid Leukemia

Clinical chemistry (Baltimore, Md.), 2017-02, Vol.63 (2), p.525-531

2017

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Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine

Clinical chemistry (Baltimore, Md.), 2018-09, Vol.64 (9), p.1296-1307

2018

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Applicability of Control Materials To Support Gene Promoter Characterization and Expression in Engineered Cells Using Digital PCR

Analytical chemistry (Washington), 2022-04, Vol.94 (14), p.5566-5574

2022

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Highly Reproducible Absolute Quantification of Mycobacterium tuberculosis Complex by Digital PCR

Analytical chemistry (Washington), 2015-04, Vol.87 (7), p.3706-3713

2015

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Pushing the Envelope with Clinical Use of Digital PCR

Clinical chemistry (Baltimore, Md.), 2021-07, Vol.67 (7), p.921-923

2021

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A comparison of miRNA isolation and RT-qPCR technologies and their effects on quantification accuracy and repeatability

BioTechniques, 2013-03, Vol.54 (3), p.155-164

2013

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Characterization of AAV vectors: A review of analytical techniques and critical quality attributes

Molecular therapy. Methods & clinical development, 2024-09, Vol.32 (3), p.101309, Article 101309

2024

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Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples

Journal of clinical microbiology, 2016-02, Vol.54 (2), p.392-400

2016

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Digital PCR can augment the interpretation of RT-qPCR Cq values for SARS-CoV-2 diagnostics

Methods (San Diego, Calif.), 2022-05, Vol.201, p.5-14

2022

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Instability of 8E5 calibration standard revealed by digital PCR risks inaccurate quantification of HIV DNA in clinical samples by qPCR

Scientific reports, 2017-04, Vol.7 (1), p.1209-7, Article 1209

2017

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Control Materials and Digital PCR Methods for Evaluation of Circulating Cell-Free DNA Extractions from Plasma

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1768, p.45

2018

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Comparison of SARS-CoV-2 N gene real-time RT-PCR targets and commercially available mastermixes

Journal of virological methods, 2021-09, Vol.295, p.114215-114215, Article 114215

2021

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A standardised methodology for the extraction and quantification of cell-free DNA in cerebrospinal fluid and application to evaluation of Alzheimer’s disease and brain cancers

New biotechnology, 2022-12, Vol.72, p.97-106

2022

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International Comparison of Enumeration-Based Quantification of DNA Copy-Concentration Using Flow Cytometric Counting and Digital Polymerase Chain Reaction

Analytical chemistry (Washington), 2016-12, Vol.88 (24), p.12169-12176

2016

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The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

Genome medicine, 2016-12, Vol.8 (1), p.132-132, Article 132

2016

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Standards and Metrology for Viral Vectors as Molecular Tools: Outcomes from a CCQM Workshop

Biologics (Basel, Switzerland), 2024-05, Vol.4 (2), p.187-201

2024

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Next-Generation Sequencing-Assisted DNA-Based Digital PCR for a Personalized Approach to the Detection and Quantification of Residual Disease in Chronic Myeloid Leukemia Patients

The Journal of molecular diagnostics : JMD, 2016-03, Vol.18 (2), p.176-189

2016

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Methods for applying accurate digital PCR analysis on low copy DNA samples

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA

The Digital MIQE Guidelines Update: Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020

Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

Digital PCR as a novel technology and its potential implications for molecular diagnostics

Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification

Fundamentals of multiplexing with digital PCR

RT-qPCR and RT-Digital PCR: A Comparison of Different Platforms for the Evaluation of Residual Disease in Chronic Myeloid Leukemia

Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine

Applicability of Control Materials To Support Gene Promoter Characterization and Expression in Engineered Cells Using Digital PCR

Highly Reproducible Absolute Quantification of Mycobacterium tuberculosis Complex by Digital PCR

Pushing the Envelope with Clinical Use of Digital PCR

A comparison of miRNA isolation and RT-qPCR technologies and their effects on quantification accuracy and repeatability

Characterization of AAV vectors: A review of analytical techniques and critical quality attributes

Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples

Digital PCR can augment the interpretation of RT-qPCR Cq values for SARS-CoV-2 diagnostics

Instability of 8E5 calibration standard revealed by digital PCR risks inaccurate quantification of HIV DNA in clinical samples by qPCR

Control Materials and Digital PCR Methods for Evaluation of Circulating Cell-Free DNA Extractions from Plasma

International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant

Comparison of SARS-CoV-2 N gene real-time RT-PCR targets and commercially available mastermixes

A standardised methodology for the extraction and quantification of cell-free DNA in cerebrospinal fluid and application to evaluation of Alzheimer’s disease and brain cancers

International Comparison of Enumeration-Based Quantification of DNA Copy-Concentration Using Flow Cytometric Counting and Digital Polymerase Chain Reaction

The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

Standards and Metrology for Viral Vectors as Molecular Tools: Outcomes from a CCQM Workshop

Next-Generation Sequencing-Assisted DNA-Based Digital PCR for a Personalized Approach to the Detection and Quantification of Residual Disease in Chronic Myeloid Leukemia Patients

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