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The role of Toll-like receptor 2 in microbial disease and immunity

Vaccine, 2003-06, Vol.21 (S2), p.S55-S60

Wetzler, Lee M.

2003

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Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

The Journal of immunology (1950), 2013-02, Vol.190 (3), p.1148-1157

2013

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Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge

International journal of infectious diseases, 2020-10, Vol.99, p.28-33

2020

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The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation

Scientific reports, 2017-04, Vol.7 (1), p.736-736, Article 736

2017

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Toll-Like Receptor Ligand Based Adjuvant, PorB, Increases Antigen Deposition on Germinal Center Follicular Dendritic Cells While Enhancing the Follicular Dendritic Cells Network

Frontiers in immunology, 2020-06, Vol.11, p.1254-1254

2020

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CD169+ Subcapsular Macrophage Role in Antigen Adjuvant Activity

Frontiers in immunology, 2021-03, Vol.12, p.624197-624197

2021

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Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance)

Haematologica (Roma), 2014-01, Vol.99 (1), p.111-115

2014

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Innate immune function of the neisserial porins and the relationship to vaccine adjuvant activity

Future microbiology, 2010-05, Vol.5 (5), p.749-758

Wetzler, Lee M

2010

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The role of porins in neisserial pathogenesis and immunity

Trends in microbiology (Regular ed.), 2003-02, Vol.11 (2), p.87-93

2003

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Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases

BMC genomics, 2018-08, Vol.19 (1), p.627-627, Article 627

2018

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Discontinuation of Systematic Surveillance and Contact Precautions for Vancomycin-Resistant Enterococcus (VRE) and Its Impact on the Incidence of VRE faecium Bacteremia in Patients with Hematologic Malignancies

Infection control and hospital epidemiology, 2016-04, Vol.37 (4), p.398-403

2016

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Neisserial PorB immune enhancing activity and use as a vaccine adjuvant

Human vaccines & immunotherapeutics, 2019-11, Vol.15 (11), p.2778-2781

2019

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Characterizing adjuvants’ effects at murine immunoglobulin repertoire level

iScience, 2024-01, Vol.27 (1), p.108749-108749, Article 108749

2024

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Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling

Journal of Immunology, 2006-02, Vol.176 (4), p.2373-2380

2006

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Neisseria meningitidis Porin PorB Interacts with Mitochondria and Protects Cells from Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (16), p.9070-9075

2000

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Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent

The Journal of immunology (1950), 2002-02, Vol.168 (4), p.1533-1537

2002

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In Vitro Pre-Clinical Evaluation of a Gonococcal Trivalent Candidate Vaccine Identified by Transcriptomics

Vaccines (Basel), 2023-12, Vol.11 (12), p.1846

2023

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Biologic features and treatment outcome of secondary acute lymphoblastic leukemia—a review of 101 cases

Annals of oncology, 2008-09, Vol.19 (9), p.1634-1638

2008

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Neisserial Porin-Induced Dendritic Cell Activation Is MyD88 and TLR2 Dependent

The Journal of immunology (1950), 2005-03, Vol.174 (6), p.3545-3550

2005

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Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition

Journal of structural biology, 2014-03, Vol.185 (3), p.440-447

2014

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Meningococcal PorB induces a robust and diverse antigen specific T cell response as a vaccine adjuvant

Vaccine, 2018-11, Vol.36 (50), p.7689-7699

2018

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Human Airway Epithelial Cell Responses to Neisseria lactamica and Purified Porin via Toll-Like Receptor 2-Dependent Signaling

Infection and Immunity, 2010-12, Vol.78 (12), p.5314-5323

2010

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The Amino Acid Sequence of Neisseria lactamica PorB Surface-Exposed Loops Influences Toll-Like Receptor 2-Dependent Cell Activation

Infection and Immunity, 2012-10, Vol.80 (10), p.3417-3428

2012

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Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins

Infection and Immunity, 2009-09, Vol.77 (9), p.3602-3610

2009

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Meningococcal Porin PorB Prevents Cellular Apoptosis in a Toll-Like Receptor 2- and NF-κB-Independent Manner

Infection and Immunity, 2010-03, Vol.78 (3), p.994-1003

2010

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The role of Toll-like receptor 2 in microbial disease and immunity

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge

The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation

Toll-Like Receptor Ligand Based Adjuvant, PorB, Increases Antigen Deposition on Germinal Center Follicular Dendritic Cells While Enhancing the Follicular Dendritic Cells Network

CD169+ Subcapsular Macrophage Role in Antigen Adjuvant Activity

Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance)

Innate immune function of the neisserial porins and the relationship to vaccine adjuvant activity

The role of porins in neisserial pathogenesis and immunity

Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases

Discontinuation of Systematic Surveillance and Contact Precautions for Vancomycin-Resistant Enterococcus (VRE) and Its Impact on the Incidence of VRE faecium Bacteremia in Patients with Hematologic Malignancies

Neisserial PorB immune enhancing activity and use as a vaccine adjuvant

Characterizing adjuvants’ effects at murine immunoglobulin repertoire level

Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling

Neisseria meningitidis Porin PorB Interacts with Mitochondria and Protects Cells from Apoptosis

Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent

In Vitro Pre-Clinical Evaluation of a Gonococcal Trivalent Candidate Vaccine Identified by Transcriptomics

Biologic features and treatment outcome of secondary acute lymphoblastic leukemia—a review of 101 cases

Neisserial Porin-Induced Dendritic Cell Activation Is MyD88 and TLR2 Dependent

Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition

Meningococcal PorB induces a robust and diverse antigen specific T cell response as a vaccine adjuvant

Human Airway Epithelial Cell Responses to Neisseria lactamica and Purified Porin via Toll-Like Receptor 2-Dependent Signaling

The Amino Acid Sequence of Neisseria lactamica PorB Surface-Exposed Loops Influences Toll-Like Receptor 2-Dependent Cell Activation

Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins

Meningococcal Porin PorB Prevents Cellular Apoptosis in a Toll-Like Receptor 2- and NF-κB-Independent Manner

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