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Structural basis for RNA replication by the hepatitis C virus polymerase

Science (American Association for the Advancement of Science), 2015-02, Vol.347 (6223), p.771-775

2015

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Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis

Protein science, 2010-10, Vol.19 (10), p.1932-1947

2010

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Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide‐binding domain 1

Protein science, 2010-10, Vol.19 (10), p.1917-1931

2010

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Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

Microbiology spectrum, 2022-04, Vol.10 (2), p.e0216721

2022

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Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening

Journal of computer-aided molecular design, 2010-12, Vol.24 (12), p.971-991

2010

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Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells

The Journal of biological chemistry, 2010-10, Vol.285 (40), p.30516-30522

2010

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Serum metabolomics indicate altered cellular energy metabolism in children with cystic fibrosis

Pediatric pulmonology, 2014-05, Vol.49 (5), p.463-472

2014

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Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant

Protein engineering, design and selection, 2010-05, Vol.23 (5), p.375-384

2010

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Industrial-scale proteomics: From liters of plasma to chemically synthesized proteins

Proteomics (Weinheim), 2004-07, Vol.4 (7), p.2125-2150

2004

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A pipeline of therapies for cystic fibrosis

Seminars in respiratory and critical care medicine, 2009-10, Vol.30 (5), p.611-626

2009

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MetaMiner (CF): a disease-oriented bioinformatics analysis environment

Methods in molecular biology (Clifton, N.J.), 2009-01, Vol.563, p.353

2009

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Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

Biochemistry (Easton), 1994-08, Vol.33 (34), p.10229-10248

1994

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Roles of the Propeptide and Metal Ions in the Folding and Stability of the Catalytic Domain of Stromelysin (Matrix Metalloproteinase 3)

Biochemistry (Easton), 1996-05, Vol.35 (21), p.6549-6558

1996

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Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane

Journal of proteome research, 2014-11, Vol.13 (11), p.4676-4685

2014

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Serum metabolomics indicate altered cellular energy metabolism in children with cystic fibrosis: Serum Metabolomics in Children with CF

Pediatric pulmonology, 2014-05, Vol.49 (5), p.463-472

2014

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The role of the pro‐sequence in the processing and secretion of the thermolysin‐like neutral protease from Bacillus cereus

Molecular microbiology, 1992-06, Vol.6 (12), p.1593-1604

1992

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Cystic Fibrosis Foundation: Achieving the Mission

Respiratory care, 2009-06, Vol.54 (6), p.788-795

2009

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Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase

Science (American Association for the Advancement of Science), 2015-02, Vol.347 (6223), p.771-775

2015

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Interactions between an inflammatory response to infection and protein trafficking pathways favor correction of defective protein trafficking in Cystic Fibrosis

Bioinformation, 2010-11, Vol.5 (6), p.228-233

2010

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The efficiency of processing and secretion of the thermolysin‐like neutral protease from Bacillus cereus does not require the whole prosequence, but does depend on the nature of the amino acid sequence in the region of the cleavage site

Molecular microbiology, 1994-06, Vol.12 (5), p.747-759

1994

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Mutational analysis of the thermolysin-like neutral protease from Bacillus cereus: The role of calcium, the pro-sequence, and the catalytic residue Glu 144

Wetmore, Diana Ruth

1993

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Pro-Sequences of Thermolysin-like neutral proteases modulate the production of active mature protease

Protein engineering, design and selection, 1993, Vol.6 (Supplement), p.34-34

1993

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Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas

Cancer research (Chicago, Ill.), 2013-10, Vol.73 (20), p.6219-6229

2013

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Iatrogenic ocular trauma associated with infraorbital block performed for rhinoscopy in a cat: case report and preliminary imaging findings

JFMS open reports, 2021-01, Vol.7 (1), p.20551169211011456-20551169211011456

2021

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Ketogenic Diet Intervention Improves Sleep in Patients with Relapsing Multiple Sclerosis (P8-3.009)

Neurology, 2023-04, Vol.100 (17_supplement_2)

2023

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Structural basis for RNA replication by the hepatitis C virus polymerase

Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis

Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide‐binding domain 1

Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening

Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells

Serum metabolomics indicate altered cellular energy metabolism in children with cystic fibrosis

Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant

Industrial-scale proteomics: From liters of plasma to chemically synthesized proteins

A pipeline of therapies for cystic fibrosis

MetaMiner (CF): a disease-oriented bioinformatics analysis environment

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

Roles of the Propeptide and Metal Ions in the Folding and Stability of the Catalytic Domain of Stromelysin (Matrix Metalloproteinase 3)

Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane

Serum metabolomics indicate altered cellular energy metabolism in children with cystic fibrosis: Serum Metabolomics in Children with CF

The role of the pro‐sequence in the processing and secretion of the thermolysin‐like neutral protease from Bacillus cereus

Cystic Fibrosis Foundation: Achieving the Mission

Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase

Interactions between an inflammatory response to infection and protein trafficking pathways favor correction of defective protein trafficking in Cystic Fibrosis

The efficiency of processing and secretion of the thermolysin‐like neutral protease from Bacillus cereus does not require the whole prosequence, but does depend on the nature of the amino acid sequence in the region of the cleavage site

Mutational analysis of the thermolysin-like neutral protease from Bacillus cereus: The role of calcium, the pro-sequence, and the catalytic residue Glu 144

Pro-Sequences of Thermolysin-like neutral proteases modulate the production of active mature protease

Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas

Iatrogenic ocular trauma associated with infraorbital block performed for rhinoscopy in a cat: case report and preliminary imaging findings

Ketogenic Diet Intervention Improves Sleep in Patients with Relapsing Multiple Sclerosis (P8-3.009)

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