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Current and future treatment of amyloid diseases

Journal of internal medicine, 2016-08, Vol.280 (2), p.177-202

2016

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Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets

Diabetologia, 2006-06, Vol.49 (6), p.1237-1246

2006

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Islet Amyloid Polypeptide: Pinpointing Amino Acid Residues Linked to Amyloid Fibril Formation

Proceedings of the National Academy of Sciences - PNAS, 1990-07, Vol.87 (13), p.5036-5040

1990

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Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes

Diabetologia, 2007-01, Vol.50 (1), p.195-201

2007

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Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

Diabetologia, 1989-04, Vol.32 (4), p.240-244

1989

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Transmissibility of Systemic Amyloidosis by a Prion-like Mechanism

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (10), p.6979-6984

2002

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Islet Amyloid Polypeptide in Patients with Pancreatic Cancer and Diabetes

The New England journal of medicine, 1994-02, Vol.330 (5), p.313-318

1994

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Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP

Molecular medicine (Cambridge, Mass.), 2000-12, Vol.6 (12), p.998-1007

2000

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Amyloid in human islets of Langerhans: immunologic evidence that islet amyloid polypeptide is modified in amyloidogenesis

Pancreas, 2000-08, Vol.21 (2), p.212-218

2000

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[1] Staining methods for identification of amyloid in tissue

Methods in Enzymology, 1999, Vol.309, p.3-25

1999

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Insulin as an amyloid-fibril protein at sites of repeated insulin injections in a diabetic patient

Diabetologia, 1988-03, Vol.31 (3), p.158-161

1988

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Alkali-Degradation of Amyloid: An Ancient Method Useful for Making Monoclonal Antibodies Against Amyloid Fibril Proteins

Scandinavian journal of immunology, 2009-12, Vol.70 (6), p.535-540

2009

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Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide

Amyloid, 2001, Vol.8 (4), p.242-249

2001

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The N-terminal segment of protein AA determines its fibrillogenic property

Biochemical and biophysical research communications, 1992-01, Vol.182 (1), p.27-33

1992

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Medin: An Integral Fragment of Aortic Smooth Muscle Cell-Produced Lactadherin Forms the Most Common Human Amyloid

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (15), p.8669-8674

1999

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Altered immunoreactivity of islet amyloid polypeptide (IAPP) may reflect major modifications of the IAPP molecule in amyloidogenesis

Diabetologia, 1997-07, Vol.40 (7), p.793-801

1997

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Massive Vascular AA‐Amyloidosis: A Histologically and Biochemically Distinctive Subtype of Reactive Systemic Amyloidosis

Scandinavian journal of immunology, 1989-11, Vol.30 (5), p.605-613

1989

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Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM)

FEBS letters, 1993-05, Vol.323 (1), p.40-44

1993

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Serum amyloid A and protein AA: Molecular mechanisms of a transmissible amyloidosis

FEBS letters, 2009-08, Vol.583 (16), p.2685-2690

2009

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AA-amyloidosis. Tissue component-specific association of various protein AA subspecies and evidence of a fourth SAA gene product

The American journal of pathology, 1990-08, Vol.137 (2), p.377-383

1990

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Expression of cone transducin, Gzα, and other G-protein α-subunit messenger ribonucleic acids in pancreatic islets

Endocrinology (Philadelphia), 1994-07, Vol.135 (1), p.31-37

1994

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Increased Release of IAPP in Response to Long-Term High Fat Intake in Mice

Hormone and metabolic research, 1998-05, Vol.30 (5), p.256-258

1998

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Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

FEBS letters, 1996-02, Vol.379 (3), p.203-206

1996

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Codeposition of Apolipoprotein A-IV and Transthyretin in Senile Systemic (ATTR) Amyloidosis

Biochemical and biophysical research communications, 2001-07, Vol.285 (4), p.903-908

2001

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Immunohistochemical identification of heparan sulphate proteoglycan in secondary systemic amyloidosis

Clinical and experimental immunology, 1988-08, Vol.73 (2), p.333-337

1988

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Current and future treatment of amyloid diseases

Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets

Islet Amyloid Polypeptide: Pinpointing Amino Acid Residues Linked to Amyloid Fibril Formation

Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes

Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

Transmissibility of Systemic Amyloidosis by a Prion-like Mechanism

Islet Amyloid Polypeptide in Patients with Pancreatic Cancer and Diabetes

Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP

Amyloid in human islets of Langerhans: immunologic evidence that islet amyloid polypeptide is modified in amyloidogenesis

[1] Staining methods for identification of amyloid in tissue

Insulin as an amyloid-fibril protein at sites of repeated insulin injections in a diabetic patient

Alkali-Degradation of Amyloid: An Ancient Method Useful for Making Monoclonal Antibodies Against Amyloid Fibril Proteins

Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide

The N-terminal segment of protein AA determines its fibrillogenic property

Medin: An Integral Fragment of Aortic Smooth Muscle Cell-Produced Lactadherin Forms the Most Common Human Amyloid

Altered immunoreactivity of islet amyloid polypeptide (IAPP) may reflect major modifications of the IAPP molecule in amyloidogenesis

Massive Vascular AA‐Amyloidosis: A Histologically and Biochemically Distinctive Subtype of Reactive Systemic Amyloidosis

Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM)

Serum amyloid A and protein AA: Molecular mechanisms of a transmissible amyloidosis

AA-amyloidosis. Tissue component-specific association of various protein AA subspecies and evidence of a fourth SAA gene product

Expression of cone transducin, Gzα, and other G-protein α-subunit messenger ribonucleic acids in pancreatic islets

Increased Release of IAPP in Response to Long-Term High Fat Intake in Mice

Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

Codeposition of Apolipoprotein A-IV and Transthyretin in Senile Systemic (ATTR) Amyloidosis

Immunohistochemical identification of heparan sulphate proteoglycan in secondary systemic amyloidosis

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