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Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

Science (American Association for the Advancement of Science), 2001-03, Vol.291 (5511), p.2162-2165

2001

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Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family

BBA - Molecular Cell Research, 2002-11, Vol.1592 (3), p.265-280

2002

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IRAK-4: A Novel Member of the IRAK Family with the Properties of an IRAK-Kinase

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.5567-5572

2002

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Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

The Journal of biological chemistry, 1999-06, Vol.274 (25), p.17406-17409

1999

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Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

The Journal of experimental medicine, 1998-12, Vol.188 (11), p.2091-2097

1998

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Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.5227-5236

2004

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Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

Nature (London), 2002-04, Vol.416 (6882), p.750-756

2002

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Preclinical and Nonclinical Characterization of HPN217: A Tri-Specific T Cell Activating Construct (TriTAC) Targeting B Cell Maturation Antigen (BCMA) for the Treatment of Multiple Myeloma

Blood, 2018-11, Vol.132 (Supplement 1), p.3225-3225

2018

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Cutting Edge: Inflammatory Signaling by Borrelia burgdorferi Lipoproteins Is Mediated by Toll-Like Receptor 2

The Journal of immunology (1950), 1999-09, Vol.163 (5), p.2382-2386

1999

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MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

Immunity (Cambridge, Mass.), 1997-12, Vol.7 (6), p.837-847

1997

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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.2842-2845

2006

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Metastatic Properties and Genomic Amplification of the Tyrosine Kinase Gene ACK1

Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (44), p.15901-15906

2005

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IRAK-M Is a Novel Member of the Pelle/Interleukin-1 Receptor-associated Kinase (IRAK) Family

The Journal of biological chemistry, 1999-07, Vol.274 (27), p.19403-19410

1999

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Co-expression of mRNA for type I and type II Interleukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness

FEBS letters, 1996-08, Vol.391 (1), p.104-108

1996

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Effects of IL-1 receptor accessory protein on IL-1 binding

FEBS letters, 1998-06, Vol.429 (3), p.303-306

1998

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Characterization of Pellino2, a substrate of IRAK1 and IRAK4

FEBS letters, 2003-07, Vol.547 (1), p.157-161

2003

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The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

The Journal of biological chemistry, 1997-03, Vol.272 (12), p.7727-7731

1997

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A critical role for interleukin‐1 receptor accessory protein in interleukin‐1 signaling

European journal of immunology, 1997-01, Vol.27 (1), p.262-267

1997

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The Type II IL-1 Receptor Interacts with the IL-1 Receptor Accessory Protein: A Novel Mechanism of Regulation of IL-1 Responsiveness

The Journal of immunology (1950), 1998-12, Vol.161 (12), p.6871-6877

1998

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High throughput screening for protein kinase inhibitors

Combinatorial chemistry & high throughput screening, 2005-03, Vol.8 (2), p.181-195

2005

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Identification of Essential Regions in the Cytoplasmic Tail of Interleukin-1 Receptor Accessory Protein Critical for Interleukin-1 Signaling

The Journal of biological chemistry, 2002-05, Vol.277 (19), p.16456-16463

2002

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Tetanus Immunity in Older Adults

Public health Nursing, 1992-06, Vol.9 (2), p.125-127

1992

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Effects of overexpression of IL‐1 receptor‐associated kinase on NFκB activation, IL‐2 production and stress‐activated protein kinases in the murine T cell line EL4

European journal of immunology, 1998-10, Vol.28 (10), p.3100-3109

1998

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Pharmacokinetics and pharmacodynamics of single oral doses of ibopamine, quinidine and their combination in normal man

European journal of clinical pharmacology, 1988-07, Vol.34 (4), p.415-418

1988

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Effects of overexpression of IL-1 receptor-associated kinase on NFkappaB activation, IL-2 production and stress-activated protein kinases in the murine T cell line EL4

European journal of immunology, 1998-10, Vol.28 (10), p.3100

1998

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Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family

IRAK-4: A Novel Member of the IRAK Family with the Properties of an IRAK-Kinase

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

Preclinical and Nonclinical Characterization of HPN217: A Tri-Specific T Cell Activating Construct (TriTAC) Targeting B Cell Maturation Antigen (BCMA) for the Treatment of Multiple Myeloma

Cutting Edge: Inflammatory Signaling by Borrelia burgdorferi Lipoproteins Is Mediated by Toll-Like Receptor 2

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4

Metastatic Properties and Genomic Amplification of the Tyrosine Kinase Gene ACK1

IRAK-M Is a Novel Member of the Pelle/Interleukin-1 Receptor-associated Kinase (IRAK) Family

Co-expression of mRNA for type I and type II Interleukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness

Effects of IL-1 receptor accessory protein on IL-1 binding

Characterization of Pellino2, a substrate of IRAK1 and IRAK4

The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

A critical role for interleukin‐1 receptor accessory protein in interleukin‐1 signaling

The Type II IL-1 Receptor Interacts with the IL-1 Receptor Accessory Protein: A Novel Mechanism of Regulation of IL-1 Responsiveness

High throughput screening for protein kinase inhibitors

Identification of Essential Regions in the Cytoplasmic Tail of Interleukin-1 Receptor Accessory Protein Critical for Interleukin-1 Signaling

Tetanus Immunity in Older Adults

Effects of overexpression of IL‐1 receptor‐associated kinase on NFκB activation, IL‐2 production and stress‐activated protein kinases in the murine T cell line EL4

Pharmacokinetics and pharmacodynamics of single oral doses of ibopamine, quinidine and their combination in normal man

Effects of overexpression of IL-1 receptor-associated kinase on NFkappaB activation, IL-2 production and stress-activated protein kinases in the murine T cell line EL4

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