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Practice of Medicinal Chemistry (3rd Edition)

Wermuth, Camille Georges

3rd ed., 2008

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Practice of Medicinal Chemistry (4th Edition)

Camille Georges Wermuth, David Aldous, Pierre Raboisson, Didier Rognan / Camille Georges Wermuth, David Aldous, Pierre Raboisson, Didier Rognan

4, 2015

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The Practice of Medicinal Chemistry

Wermuth, Camille Georges

2nd Edition, 2003

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Palladium-Catalysed Cross-Coupling Reactions on Pyridazine Moieties

Synlett, 2006-12, Vol.2006 (19), p.3185-3204

2006

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Search for new lead compounds: The example of the chemical and pharmacological dissection of aminopyridazines

Journal of heterocyclic chemistry, 1998-09, Vol.35 (5), p.1091-1100

Wermuth, Camille-Georges

1998

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A Convenient 3-Step Synthesis of 3-Acetamido-6-arylpyridazines Directed to Novel Y5 Receptor Antagonist

Chemical and Pharmaceutical Bulletin, 2002, Vol.50(5), pp.636-639

2002

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Synthesis of constrained arylpiperidines using intramolecular Heck or radical reactions

Tetrahedron letters, 2001-09, Vol.42 (37), p.6499-6502

2001

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The synthesis of α-amino-γ-substituted adipic acids: stereoelectronic effects during the 1,4-addition of organocuprates to methyl N-tert-butoxy-6-oxo-1,2,3,6-tetrahydropyridine-2-carboxylate

Chemical communications (Cambridge, England), 1999-04 (8), p.683

1999

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Diastereoselectivity in conjugate addition of alkylcuprates to vinylogous ester of N O-diprotected serinal

Tetrahedron letters, 1990, Vol.31 (7), p.1011-1014

1990

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1,3-diastereocontrol with bromoallenes. Synthesis of enantiomerically pure β-branched α-amino acids

Tetrahedron letters, 1994-10, Vol.35 (42), p.7775-7778

1994

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From phenylaziridine to phenylkainoids. A formal synthesis of (±)-phenylkainic acid

Tetrahedron letters, 1999-05, Vol.40 (20), p.3873-3876

1999

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Chapter 36. Glossary of Terms Used in Medicinal Chemistry (IUPAC Recommendations 1997

Annual Reports in Medicinal Chemistry, 1998, Vol.33, p.385-395

1998

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Fragmentation of N-Boc arylpiperazines under basic conditions

Tetrahedron letters, 1997-01, Vol.38 (1), p.63-64

1997

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Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement

Journal of computer-aided molecular design, 1997-07, Vol.11 (4), p.317-332

1997

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Selective Optimization of Side Activities (SOSA): A Promising way for Drug Discovery

Polypharmacology in Drug Discovery, 2012, p.227-243

2012

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Stereoselective synthesis of 3-alkylated glutamic acids: application to the synthesis of secokainic acid

Journal of organic chemistry, 1991-09, Vol.56 (19), p.5729-5733

1991

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Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogs

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1450-1457

1989

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Synthesis of 2- or/and 6-Methylated Analogues of Isoguvacine (1,2,3,6-Tetrahydropyridine-4-carboxylic Acid) a GABAA Agonist

Heterocycles, 1996, Vol.43 (10), p.2131

1996

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The active analog approach applied to the pharmacophore identification of benzodiazepine receptor ligands

Journal of computer-aided molecular design, 1987-07, Vol.1 (2), p.153-170

1987

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Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of .gamma.-aminobutyric acid acting as selective GABA-A antagonists

Journal of medicinal chemistry, 1987-02, Vol.30 (2), p.239-249

1987

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Convenient Preparation of 3-Methoxycarbonylpyridazines by Palladium Catalyzed Alkoxycarbonylation of Pyridazinetriflates

Heterocycles, 1996, Vol.43 (7), p.1459

1996

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Ortho-directed Metalation of 3-Heterosubstituted 4-Methyl-6-phenylpyridazines

Heterocycles, 1994-12, Vol.39 (1), p.271

1994

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Synthesis of [3H]-labelled trans 4-hydroxycrotonic acid (T-HCA), an endogenous substance interfering with 4-hydroxybutyrate (GHB)

Journal of labelled compounds & radiopharmaceuticals, 1989-01, Vol.27 (1), p.23-33

1989

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Optically active benzamides as predictive tools for mapping the dopamine D2 receptor

European journal of pharmacology, 1990-07, Vol.189 (1), p.59-70

1990

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SR 46559A : a novel and potent muscarinic compound with no cholinergic syndrome

Psychopharmacologia, 1993-09, Vol.112 (2-3), p.219-227

1993

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Practice of Medicinal Chemistry (3rd Edition)

Practice of Medicinal Chemistry (4th Edition)

The Practice of Medicinal Chemistry

Palladium-Catalysed Cross-Coupling Reactions on Pyridazine Moieties

Search for new lead compounds: The example of the chemical and pharmacological dissection of aminopyridazines

A Convenient 3-Step Synthesis of 3-Acetamido-6-arylpyridazines Directed to Novel Y5 Receptor Antagonist

Synthesis of constrained arylpiperidines using intramolecular Heck or radical reactions

The synthesis of α-amino-γ-substituted adipic acids: stereoelectronic effects during the 1,4-addition of organocuprates to methyl N-tert-butoxy-6-oxo-1,2,3,6-tetrahydropyridine-2-carboxylate

Diastereoselectivity in conjugate addition of alkylcuprates to vinylogous ester of N O-diprotected serinal

1,3-diastereocontrol with bromoallenes. Synthesis of enantiomerically pure β-branched α-amino acids

From phenylaziridine to phenylkainoids. A formal synthesis of (±)-phenylkainic acid

Chapter 36. Glossary of Terms Used in Medicinal Chemistry (IUPAC Recommendations 1997

Fragmentation of N-Boc arylpiperazines under basic conditions

Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement

Selective Optimization of Side Activities (SOSA): A Promising way for Drug Discovery

Stereoselective synthesis of 3-alkylated glutamic acids: application to the synthesis of secokainic acid

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogs

Synthesis of 2- or/and 6-Methylated Analogues of Isoguvacine (1,2,3,6-Tetrahydropyridine-4-carboxylic Acid) a GABAA Agonist

The active analog approach applied to the pharmacophore identification of benzodiazepine receptor ligands

Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of .gamma.-aminobutyric acid acting as selective GABA-A antagonists

Convenient Preparation of 3-Methoxycarbonylpyridazines by Palladium Catalyzed Alkoxycarbonylation of Pyridazinetriflates

Ortho-directed Metalation of 3-Heterosubstituted 4-Methyl-6-phenylpyridazines

Synthesis of [3H]-labelled trans 4-hydroxycrotonic acid (T-HCA), an endogenous substance interfering with 4-hydroxybutyrate (GHB)

Optically active benzamides as predictive tools for mapping the dopamine D2 receptor

SR 46559A : a novel and potent muscarinic compound with no cholinergic syndrome

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