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Patients with infective endocarditis undergoing cardiac surgery have distinct ROTEM profiles and more bleeding complications compared to patients without infective endocarditis

PloS one, 2023-04, Vol.18 (4), p.e0284329-e0284329

2023

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Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor

Clinical pharmacology and therapeutics, 2005-10, Vol.78 (4), p.412-421

2005

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First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

The European respiratory journal, 2009-04, Vol.33 (4), p.785-792

2009

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Variability of Clinical Chemistry Parameters in Healthy Volunteers – An Overview of Bayer in-house Phase I Trials from 2000 – 2013

Clinical therapeutics, 2017-08, Vol.39 (8), p.e19-e19

2017

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Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers

Clinical pharmacology: advances and applications, 2014-01, Vol.6 (default), p.51-59

2014

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First‐in‐man–proof of concept study with molidustat: a novel selective oral HIF‐prolyl hydroxylase inhibitor for the treatment of renal anaemia

British journal of clinical pharmacology, 2018-07, Vol.84 (7), p.1557-1565

2018

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Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic (TRACE II): study protocol for a multicentre prospective observational study

BMJ open, 2022-06, Vol.12 (6), p.e060354-e060354

2022

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A Comparison of 1000 Hz to 30 Hz Spinal Cord Stimulation Strategies in Patients with Unilateral Neuropathic Leg Pain Due to Failed Back Surgery Syndrome: A Multicenter, Randomized, Double-Blinded, Crossover Clinical Study (HALO)

Pain and therapy, 2021-12, Vol.10 (2), p.1189-1202

2021

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Incidence, Severity and Clinical Factors Associated with Hypotension in Patients Admitted to an Intensive Care Unit: A Prospective Observational Study

Journal of clinical medicine, 2022-11, Vol.11 (22), p.6832

2022

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First-In-Man Dose Escalation Study of Aspirin® Inhaled For The Clinical Development of A New Antiviral Treatment of Resistant Influenza

Clinical therapeutics, 2015-08, Vol.37 (8), p.e155-e155

2015

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Study protocol for the TRUSt trial: a pragmatic randomised controlled trial comparing the standard of care with a transitional pain service for patients at risk of chronic postsurgical pain undergoing surgery

BMJ open, 2021-08, Vol.11 (8), p.e049676-e049676

2021

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Prospective Observational Cohort Study on Dorsal Root Ganglion Stimulation in Chronic Postsurgical Pain: Results of Patient-Reported Outcomes at Two Years

Neuromodulation (Malden, Mass.), 2022-10, Vol.25 (7), p.998-1005

2022

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Psychometric evaluation of the Dutch 40-item Quality-of-Recovery scale

British journal of anaesthesia : BJA, 2022-01, Vol.128 (1), p.e6-e8

2022

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Repinotan, a Selective 5-HT1A-R-Agonist, Antagonizes Morphine-Induced Ventilatory Depression in Anesthetized Rats

Anesthesia and analgesia, 2010-10, Vol.111 (4), p.901-907

2010

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The safety of healthy volunteers in First-in-Man trials - an analysis of studies conducted at the Bayer in-house ward from 2000 to 2005

International journal of clinical pharmacology and therapeutics, 2010-09, Vol.48 (9), p.563

2010

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Surveillance of high-risk early postsurgical patients for real-time detection of complications using wireless monitoring (SHEPHERD study): results of a randomized multicenter stepped wedge cluster trial

Frontiers in medicine, 2023, Vol.10, p.1295499-1295499

2023

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Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects

International journal of clinical pharmacology and therapeutics, 2005-05, Vol.43 (5), p.217

2005

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Vardenafil Increases Penile Rigidity and Tumescence in Men with Erectile Dysfunction after a Single Oral Dose

European urology, 2001-08, Vol.40 (2), p.181-190

2001

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Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939 : an oral, direct Factor Xa inhibitor-after multiple dosing in healthy male subjects

European journal of clinical pharmacology, 2005-12, Vol.61 (12), p.873-880

2005

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Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients : a RigiScan and pharmacokinetic study

World journal of urology, 2001-02, Vol.19 (1), p.32-39

2001

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Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype

International journal of clinical pharmacology and therapeutics, 2004-02, Vol.42 (2), p.73

2004

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Single-Dose Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Stimulator BAY 63-2521: An Ascending-Dose Study in Healthy Male Volunteers

Journal of clinical pharmacology, 2008-08, Vol.48 (8), p.926-934

2008

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Who is a ‘healthy subject’?—consensus results on pivotal eligibility criteria for clinical trials

European Journal of Clinical Pharmacology, 2017-04, Vol.73 (4), p.409-416

2017

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Phase I studies in patients with liver cirrhosis

International journal of clinical pharmacology and therapeutics, 1998-11, Vol.36 (11), p.599

Wensing, G

1998

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Urinary sodium balance in patients with cirrhosis: Relationship to quantitative parameters of liver function

Hepatology (Baltimore, Md.), 1997-11, Vol.26 (5), p.1149-1155

1997

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Patients with infective endocarditis undergoing cardiac surgery have distinct ROTEM profiles and more bleeding complications compared to patients without infective endocarditis

Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

Variability of Clinical Chemistry Parameters in Healthy Volunteers – An Overview of Bayer in-house Phase I Trials from 2000 – 2013

Pharmacokinetics and pharmacodynamics of acetylsalicylic acid after intravenous and oral administration to healthy volunteers

First‐in‐man–proof of concept study with molidustat: a novel selective oral HIF‐prolyl hydroxylase inhibitor for the treatment of renal anaemia

Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic (TRACE II): study protocol for a multicentre prospective observational study

A Comparison of 1000 Hz to 30 Hz Spinal Cord Stimulation Strategies in Patients with Unilateral Neuropathic Leg Pain Due to Failed Back Surgery Syndrome: A Multicenter, Randomized, Double-Blinded, Crossover Clinical Study (HALO)

Incidence, Severity and Clinical Factors Associated with Hypotension in Patients Admitted to an Intensive Care Unit: A Prospective Observational Study

First-In-Man Dose Escalation Study of Aspirin® Inhaled For The Clinical Development of A New Antiviral Treatment of Resistant Influenza

Study protocol for the TRUSt trial: a pragmatic randomised controlled trial comparing the standard of care with a transitional pain service for patients at risk of chronic postsurgical pain undergoing surgery

Prospective Observational Cohort Study on Dorsal Root Ganglion Stimulation in Chronic Postsurgical Pain: Results of Patient-Reported Outcomes at Two Years

Psychometric evaluation of the Dutch 40-item Quality-of-Recovery scale

Repinotan, a Selective 5-HT1A-R-Agonist, Antagonizes Morphine-Induced Ventilatory Depression in Anesthetized Rats

The safety of healthy volunteers in First-in-Man trials - an analysis of studies conducted at the Bayer in-house ward from 2000 to 2005

Surveillance of high-risk early postsurgical patients for real-time detection of complications using wireless monitoring (SHEPHERD study): results of a randomized multicenter stepped wedge cluster trial

Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects

Vardenafil Increases Penile Rigidity and Tumescence in Men with Erectile Dysfunction after a Single Oral Dose

Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939 : an oral, direct Factor Xa inhibitor-after multiple dosing in healthy male subjects

Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients : a RigiScan and pharmacokinetic study

Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype

Single-Dose Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Stimulator BAY 63-2521: An Ascending-Dose Study in Healthy Male Volunteers

Who is a ‘healthy subject’?—consensus results on pivotal eligibility criteria for clinical trials

Phase I studies in patients with liver cirrhosis

Urinary sodium balance in patients with cirrhosis: Relationship to quantitative parameters of liver function

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