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LC–MS bioanalysis of intact proteins and peptides

Biomedical chromatography, 2020-01, Vol.34 (1), p.e4633-n/a

2020

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Salting-out assisted liquid-liquid extraction for bioanalysis

Bioanalysis, 2013-06, Vol.5 (12), p.1583-1598

2013

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Impact of column temperature and mobile phase components on selectivity of hydrophilic interaction chromatography (HILIC)

Journal of separation science, 2008-05, Vol.31 (9), p.1449-1464

2008

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Bioanalytical liquid chromatography tandem mass spectrometry methods on underivatized silica columns with aqueous/organic mobile phases

Journal of Chromatography B, 2003-11, Vol.796 (2), p.209-224

Naidong, Weng

2003

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Simultaneous Catabolite Identification and Quantitation of Large Therapeutic Protein at the Intact Level by Immunoaffinity Capture Liquid Chromatography–High-Resolution Mass Spectrometry

Analytical chemistry (Washington), 2017-06, Vol.89 (11), p.6065-6075

2017

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Recent advances in application of hydrophilic interaction chromatography for quantitative bioanalysis

Journal of separation science, 2010-03, Vol.33 (6-7), p.681-697

2010

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Targeted Biomarker Quantitation by LC-MS

Naidong Weng, Wenying Jian

1, 2017

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Validation and application of an LC–MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-06, Vol.878 (20), p.1687-1699

2010

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Development and validation of an LC–MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-06, Vol.961, p.62-70

2014

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Relative Quantitation of Glycoisoforms of Intact Apolipoprotein C3 in Human Plasma by Liquid Chromatography–High-Resolution Mass Spectrometry

Analytical chemistry (Washington), 2013-03, Vol.85 (5), p.2867-2874

2013

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Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography–electrospray tandem mass spectrometric (HILIC–ESI/MS/MS) bioanalysis of basic compounds

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-10, Vol.825 (2), p.186-192

2005

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Target biomarker quantitation by LC-MS

First edition., 2017

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Standard-Free Bioanalytical Approach for Absolute Quantitation of Drug Metabolites Utilizing Biosynthesis of Reciprocal Radio and Stable Isotopologues and Its Application

Analytical chemistry (Washington), 2017-08, Vol.89 (16), p.8399-8404

2017

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Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC–MS/MS—A high throughput approach to evaluate drug–drug interactions

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-05, Vol.878 (15), p.1169-1177

2010

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Evaluation of a High-Throughput Online Solid Phase Extraction–Tandem Mass Spectrometry System for In Vivo Bioanalytical Studies

Analytical chemistry (Washington), 2011-11, Vol.83 (21), p.8259-8266

2011

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Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC–MS/MS quantitation of metabolites

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-12, Vol.878 (31), p.3267-3276

2010

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Bioanalysis of drug in tissue: current status and challenges

Bioanalysis, 2012-11, Vol.4 (21), p.2637-2653

2012

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Applications of high-resolution MS in bioanalysis

Bioanalysis, 2013-05, Vol.5 (10), p.1269-1276

2013

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Challenges in urine bioanalytical assays: overcoming nonspecific binding

Bioanalysis, 2010-09, Vol.2 (9), p.1573-1586

2010

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Important considerations for quantitation of small-molecule biomarkers using LC-MS

Bioanalysis, 2012-10, Vol.4 (20), p.2431-2434

2012

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Analysis of omeprazole and 5-OH omeprazole in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry (HILIC–MS/MS)—Eliminating evaporation and reconstitution steps in 96-well liquid/liquid extraction

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-01, Vol.830 (1), p.135-142

2006

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A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer

Journal of mass spectrometry., 2005-10, Vol.40 (10), p.1347-1356

2005

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Separation of amino acids, peptides and corresponding Amadori compounds on a silica column at elevated temperature

Journal of Chromatography A, 2007-04, Vol.1147 (2), p.165-171

2007

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Simultaneous determination of norethindrone and ethinyl estradiol in human plasma by high performance liquid chromatography with tandem mass spectrometry—experiences on developing a highly selective method using derivatization reagent for enhancing sensitivity

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-10, Vol.825 (2), p.223-232

2005

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Measurement of protein in vivo turnover rate with metabolic labeling using LC–MS

Biomedical chromatography, 2023-07, Vol.37 (7), p.e5583-n/a

2023

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LC–MS bioanalysis of intact proteins and peptides

Salting-out assisted liquid-liquid extraction for bioanalysis

Impact of column temperature and mobile phase components on selectivity of hydrophilic interaction chromatography (HILIC)

Bioanalytical liquid chromatography tandem mass spectrometry methods on underivatized silica columns with aqueous/organic mobile phases

Simultaneous Catabolite Identification and Quantitation of Large Therapeutic Protein at the Intact Level by Immunoaffinity Capture Liquid Chromatography–High-Resolution Mass Spectrometry

Recent advances in application of hydrophilic interaction chromatography for quantitative bioanalysis

Targeted Biomarker Quantitation by LC-MS

Validation and application of an LC–MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma

Development and validation of an LC–MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma

Relative Quantitation of Glycoisoforms of Intact Apolipoprotein C3 in Human Plasma by Liquid Chromatography–High-Resolution Mass Spectrometry

Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography–electrospray tandem mass spectrometric (HILIC–ESI/MS/MS) bioanalysis of basic compounds

Target biomarker quantitation by LC-MS

Standard-Free Bioanalytical Approach for Absolute Quantitation of Drug Metabolites Utilizing Biosynthesis of Reciprocal Radio and Stable Isotopologues and Its Application

Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC–MS/MS—A high throughput approach to evaluate drug–drug interactions

Evaluation of a High-Throughput Online Solid Phase Extraction–Tandem Mass Spectrometry System for In Vivo Bioanalytical Studies

Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC–MS/MS quantitation of metabolites

Bioanalysis of drug in tissue: current status and challenges

Applications of high-resolution MS in bioanalysis

Challenges in urine bioanalytical assays: overcoming nonspecific binding

Important considerations for quantitation of small-molecule biomarkers using LC-MS

Analysis of omeprazole and 5-OH omeprazole in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry (HILIC–MS/MS)—Eliminating evaporation and reconstitution steps in 96-well liquid/liquid extraction

A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer

Separation of amino acids, peptides and corresponding Amadori compounds on a silica column at elevated temperature

Simultaneous determination of norethindrone and ethinyl estradiol in human plasma by high performance liquid chromatography with tandem mass spectrometry—experiences on developing a highly selective method using derivatization reagent for enhancing sensitivity

Measurement of protein in vivo turnover rate with metabolic labeling using LC–MS

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