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Enhanced Catalysis of Oxime-Based Bioconjugations by Substituted Anilines

Bioconjugate chemistry, 2014-01, Vol.25 (1), p.93-101

2014

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Kinetic models towards an enhanced understanding of diverse ADC conjugation reactions

Frontiers in bioengineering and biotechnology, 2024-07, Vol.12, p.1403644

2024

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A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties

PloS one, 2016-12, Vol.11 (12), p.e0167935-e0167935

2016

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Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions

Frontiers in bioengineering and biotechnology, 2023-04, Vol.11, p.1123842

2023

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Corrigendum: Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions

Frontiers in bioengineering and biotechnology, 2023-06, Vol.11, p.1229416-1229416

2023

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Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals

Biotechnology journal, 2017-02, Vol.12 (2), p.n/a

2017

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HIV-1 Reverse Transcriptase Can Simultaneously Engage Its DNA/RNA Substrate at Both DNA Polymerase and RNase H Active Sites: Implications for RNase H Inhibition

Journal of molecular biology, 2009-05, Vol.388 (3), p.462-474

2009

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Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

Antimicrobial Agents and Chemotherapy, 2010-09, Vol.54 (9), p.3913-3921

2010

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Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin

Journal of Chromatography A, 2014-01, Vol.1325, p.171-178

2014

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Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

Biological chemistry, 2007-06, Vol.388 (6), p.617-626

2007

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Synthesis of novel NBD-GM1 and NBD-GM2 for the transfer activity of GM2-activator protein by a FRET-based assay system

Glycobiology (Oxford), 2005-12, Vol.15 (12), p.1302-1311

2005

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Using multimodal chromatography for post-conjugation antibody-drug conjugate purification: A methodology from high throughput screening to in-silico process development

Journal of Chromatography A, 2021-09, Vol.1653, p.462378, Article 462378

2021

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Hexosaminidase assays

Glycoconjugate journal, 2009-11, Vol.26 (8), p.945-952

2009

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Rational downstream development for adeno-associated virus full/empty capsid separation – A streamlined methodology based on high-throughput screening and mechanistic modeling

Journal of Chromatography A, 2024-02, Vol.1716, p.464632, Article 464632

2024

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Nucleotide Excision Repair and Template-independent Addition by HIV-1 Reverse Transcriptase in the Presence of Nucleocapsid Protein

The Journal of biological chemistry, 2006-04, Vol.281 (17), p.11736-11743

2006

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Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates

Journal of biotechnology, 2018-07, Vol.278, p.48-55

2018

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Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis

mAbs, 2019-08, Vol.11 (6), p.1064-1076

2019

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Monitoring of antibody-drug conjugation reactions with UV/Vis spectroscopy

Journal of biotechnology, 2018-12, Vol.288, p.15-22

2018

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Impact of Magnetic Stirring on Stainless Steel Integrity: Effect on Biopharmaceutical Processing

Journal of pharmaceutical sciences, 2017-11, Vol.106 (11), p.3280-3286

2017

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Evaluation of continuous nonaffinity capture chromatography for a recombinant enzyme—optimization for a changing perfusion feedstream and comparison to batch processing

Biotechnology progress, 2018-09, Vol.34 (5), p.1195-1204

2018

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Expression of the GM2-activator protein in the methylotrophic yeast Pichia pastoris, purification, isotopic labeling, and biophysical characterization

Protein expression and purification, 2004-03, Vol.34 (1), p.147-157

2004

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Expression of recombinant human GM2-activator protein in insect cells: purification and characterization by mass spectrometry

Protein expression and purification, 2003-02, Vol.27 (2), p.259-266

2003

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Camelid V sub(H)H affinity ligands enable separation of closely related biopharmaceuticals

Biotechnology journal, 2017-02, Vol.12 (2), p.np-np

2017

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Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

Biotechnology progress, 2014-11, Vol.30 (6), p.1380-1389

2014

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Camelid V H H affinity ligands enable separation of closely related biopharmaceuticals

Biotechnology journal, 2017-02, Vol.12 (2)

2017

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Enhanced Catalysis of Oxime-Based Bioconjugations by Substituted Anilines

Kinetic models towards an enhanced understanding of diverse ADC conjugation reactions

A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties

Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions

Corrigendum: Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions

Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals

HIV-1 Reverse Transcriptase Can Simultaneously Engage Its DNA/RNA Substrate at Both DNA Polymerase and RNase H Active Sites: Implications for RNase H Inhibition

Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

Synthesis of novel NBD-GM1 and NBD-GM2 for the transfer activity of GM2-activator protein by a FRET-based assay system

Using multimodal chromatography for post-conjugation antibody-drug conjugate purification: A methodology from high throughput screening to in-silico process development

Hexosaminidase assays

Rational downstream development for adeno-associated virus full/empty capsid separation – A streamlined methodology based on high-throughput screening and mechanistic modeling

Nucleotide Excision Repair and Template-independent Addition by HIV-1 Reverse Transcriptase in the Presence of Nucleocapsid Protein

Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates

Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis

Monitoring of antibody-drug conjugation reactions with UV/Vis spectroscopy

Impact of Magnetic Stirring on Stainless Steel Integrity: Effect on Biopharmaceutical Processing

Evaluation of continuous nonaffinity capture chromatography for a recombinant enzyme—optimization for a changing perfusion feedstream and comparison to batch processing

Expression of the GM2-activator protein in the methylotrophic yeast Pichia pastoris, purification, isotopic labeling, and biophysical characterization

Expression of recombinant human GM2-activator protein in insect cells: purification and characterization by mass spectrometry

Camelid V sub(H)H affinity ligands enable separation of closely related biopharmaceuticals

Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

Camelid V H H affinity ligands enable separation of closely related biopharmaceuticals

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