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The Global Portfolio of New Antimalarial Medicines Under Development

Clinical pharmacology and therapeutics, 2009-06, Vol.85 (6), p.584-595

2009

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New medicines for control and elimination of malaria

Clinical therapeutics, 2013-08, Vol.35 (8), p.e132-e132

Wells, T.N.C

2013

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Glycosaminoglycan Binding and Oligomerization Are Essential for the in vivo Activity of Certain Chemokines

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1885-1890

2003

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Chemokine blockers – therapeutics in the making?

Trends in pharmacological sciences (Regular ed.), 2006, Vol.27 (1), p.41-47

2006

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Neglected diseases and drug discovery (RSC drug discovery series, no. 14)

1, 2011

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The Platelet Collagen Receptor Glycoprotein VI Is a Member of the Immunoglobulin Superfamily Closely Related to FcαR and the Natural Killer Receptors

The Journal of biological chemistry, 1999-10, Vol.274 (41), p.29019-29024

1999

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New therapeutics that modulate chemokine networks

Nature reviews. Drug discovery, 2002-05, Vol.1 (5), p.347-358

2002

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Interference with Heparin Binding and Oligomerization Creates a Novel Anti-Inflammatory Strategy Targeting the Chemokine System

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5776-5785

2004

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Glycosaminoglycans Interact Selectively with Chemokines and Modulate Receptor Binding and Cellular Responses

Biochemistry (Easton), 1999-09, Vol.38 (39), p.12959-12968

1999

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An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo

Journal of leukocyte biology, 2008-10, Vol.84 (4), p.1101-1108

2008

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The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity

The Journal of biological chemistry, 2001-04, Vol.276 (14), p.10620-10626

2001

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Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

Science (American Association for the Advancement of Science), 1997-04, Vol.276 (5310), p.276-279

1997

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Multi-faceted strategies to combat disease by interference with the chemokine system

Trends in immunology, 2005-05, Vol.26 (5), p.268-274

2005

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Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets

Blood, 2000-12, Vol.96 (13), p.4046-4054

2000

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A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock

The Journal of experimental medicine, 2000-05, Vol.191 (10), p.1755-1764

2000

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

The Journal of experimental medicine, 1998-07, Vol.188 (1), p.157-167

1998

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Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

Biochemistry (Easton), 1997-11, Vol.36 (44), p.13570-13578

1997

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Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro

Journal of neuroimmunology, 2006-05, Vol.174 (1), p.133-146

2006

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The X-Ray Structure of RANTES: Heparin-Derived Disaccharides Allows the Rational Design of Chemokine Inhibitors

Structure (London), 2004-11, Vol.12 (11), p.2081-2093

2004

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Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

The Journal of experimental medicine, 1998-04, Vol.187 (8), p.1215-1224

1998

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A Broad-Spectrum Chemokine Antagonist Encoded by Kaposi's Sarcoma- Associated Herpesvirus

Science (American Association for the Advancement of Science), 1997-09, Vol.277 (5332), p.1656-1659

1997

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RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

The Journal of experimental medicine, 1997-04, Vol.185 (7), p.1371-1380

1997

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CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

Cell, 1996-11, Vol.87 (4), p.745-756

1996

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Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines

The Journal of immunology (1950), 1997-08, Vol.159 (4), p.1993-2000

1997

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Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-gamma in human neutrophils

The Journal of immunology (1950), 1999-01, Vol.162 (1), p.474-479

1999

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The Global Portfolio of New Antimalarial Medicines Under Development

New medicines for control and elimination of malaria

Glycosaminoglycan Binding and Oligomerization Are Essential for the in vivo Activity of Certain Chemokines

Chemokine blockers – therapeutics in the making?

Neglected diseases and drug discovery (RSC drug discovery series, no. 14)

The Platelet Collagen Receptor Glycoprotein VI Is a Member of the Immunoglobulin Superfamily Closely Related to FcαR and the Natural Killer Receptors

New therapeutics that modulate chemokine networks

Interference with Heparin Binding and Oligomerization Creates a Novel Anti-Inflammatory Strategy Targeting the Chemokine System

Glycosaminoglycans Interact Selectively with Chemokines and Modulate Receptor Binding and Cellular Responses

An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo

The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity

Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

Multi-faceted strategies to combat disease by interference with the chemokine system

Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets

A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock

The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro

The X-Ray Structure of RANTES: Heparin-Derived Disaccharides Allows the Rational Design of Chemokine Inhibitors

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

A Broad-Spectrum Chemokine Antagonist Encoded by Kaposi's Sarcoma- Associated Herpesvirus

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines

Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-gamma in human neutrophils

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