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Matrix Metalloproteinase Gelatinase B (MMP-9) Coordinates and Effects Epithelial Regeneration

The Journal of biological chemistry, 2002-01, Vol.277 (3), p.2065-2072

2002

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Matrix Metalloproteinases Generate Angiostatin: Effects on Neovascularization

The Journal of immunology (1950), 1998-12, Vol.161 (12), p.6845-6852

1998

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Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis

Circulation (New York, N.Y.), 1995-09, Vol.92 (6), p.1393-1398

1995

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The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

The Journal of cell biology, 1997-06, Vol.137 (6), p.1445-1457

1997

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Trial of Roflumilast Cream for Chronic Plaque Psoriasis

The New England journal of medicine, 2020-07, Vol.383 (3), p.229-239

2020

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Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

The Journal of biological chemistry, 1997-08, Vol.272 (35), p.22053-22058

1997

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Chlamydia pneumoniae proteins induce secretion of the 92-kDa gelatinase by human monocyte- derived macrophages

Arteriosclerosis, thrombosis, and vascular biology, 2001-01, Vol.21 (1), p.E1

2001

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Matrix Metalloproteinase Deficiencies Affect Contact Hypersensitivity: Stromelysin-1 Deficiency Prevents the Response and Gelatinase B Deficiency Prolongs the Response

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (12), p.6885-6889

1999

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15309 ARQ-151, roflumilast cream, improved psoriasis in phase 2a study

Journal of the American Academy of Dermatology, 2020-12, Vol.83 (6), p.AB146-AB146

2020

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Human Lung Tissue Macrophages, but not Alveolar Macrophages, Express Matrix Metalloproteinases after Direct Contact with Activated T Lymphocytes

American journal of respiratory cell and molecular biology, 2001-04, Vol.24 (4), p.442-451

2001

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The Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study

Journal of drugs in dermatology, 2023-02, Vol.22 (2), p.139-147

2023

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The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases

The Journal of biological chemistry, 1996-02, Vol.271 (8), p.4335-4341

1996

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Induction and Repression of Collagenase-1 by Keratinocytes Is Controlled by Distinct Components of Different Extracellular Matrix Compartments

The Journal of biological chemistry, 1997-08, Vol.272 (35), p.22103-22110

1997

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Roflumilast Cream Improves Signs and Symptoms of Plaque Psoriasis: Results from a Phase 1/2a Randomized, Controlled Study

Journal of drugs in dermatology, 2020-08, Vol.19 (8), p.734-740

2020

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Mechanisms of Hepatocyte Growth Factor Stimulation of Keratinocyte Metalloproteinase Production

The Journal of biological chemistry, 1996-10, Vol.271 (40), p.24576-24582

1996

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Induction of Macrophage Matrix Metalloproteinase Biosynthesis by Surfactant Protein D

The Journal of biological chemistry, 2001-10, Vol.276 (41), p.37846-37852

2001

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IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes

The Journal of clinical investigation, 1995-11, Vol.96 (5), p.2304-2310

1995

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Keratinocyte Collagenase-1 Expression Requires an Epidermal Growth Factor Receptor Autocrine Mechanism

The Journal of biological chemistry, 1999-04, Vol.274 (15), p.10372-10381

1999

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Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (18), p.9748-9753

1996

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Roflumilast Cream (ARQ-151) 0.15% and 0.3% Improved Burden of Signs and Symptoms in Adults With Chronic Plaque Psoriasis in a Phase 2b Study

Skin (Milwood, N.Y.), 2020-10, Vol.4 (6), p.s70

2020

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Roflumilast Cream (ARQ-151) Improved Itch Severity and Itch-Related Sleep Loss in Adults With Chronic Plaque Psoriasis in a Phase 2b Study

Skin (Milwood, N.Y.), 2020-10, Vol.4 (6), p.s71

2020

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Matrilysin expression and function in airway epithelium

The Journal of clinical investigation, 1998-10, Vol.102 (7), p.1321-1331

1998

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Role of Matrix Metalloproteinases and Their Inhibition in Cutaneous Wound Healing and Allergic Contact Hypersensitivity

Annals of the New York Academy of Sciences, 1999-06, Vol.878 (1), p.12-24

1999

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Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

The Journal of clinical investigation, 1995-07, Vol.96 (1), p.318-326

1995

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Expression of 92-kDa Type IV Collagenase mRNA by Eosinophils Associated with Basal Cell Carcinoma

Journal of investigative dermatology, 1992-10, Vol.99 (4), p.497-503

1992

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Matrix Metalloproteinase Gelatinase B (MMP-9) Coordinates and Effects Epithelial Regeneration

Matrix Metalloproteinases Generate Angiostatin: Effects on Neovascularization

Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis

The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

Trial of Roflumilast Cream for Chronic Plaque Psoriasis

Initiation of Osteoclast Bone Resorption by Interstitial Collagenase

Chlamydia pneumoniae proteins induce secretion of the 92-kDa gelatinase by human monocyte- derived macrophages

Matrix Metalloproteinase Deficiencies Affect Contact Hypersensitivity: Stromelysin-1 Deficiency Prevents the Response and Gelatinase B Deficiency Prolongs the Response

15309 ARQ-151, roflumilast cream, improved psoriasis in phase 2a study

Human Lung Tissue Macrophages, but not Alveolar Macrophages, Express Matrix Metalloproteinases after Direct Contact with Activated T Lymphocytes

The Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study

The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases

Induction and Repression of Collagenase-1 by Keratinocytes Is Controlled by Distinct Components of Different Extracellular Matrix Compartments

Roflumilast Cream Improves Signs and Symptoms of Plaque Psoriasis: Results from a Phase 1/2a Randomized, Controlled Study

Mechanisms of Hepatocyte Growth Factor Stimulation of Keratinocyte Metalloproteinase Production

Induction of Macrophage Matrix Metalloproteinase Biosynthesis by Surfactant Protein D

IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes

Keratinocyte Collagenase-1 Expression Requires an Epidermal Growth Factor Receptor Autocrine Mechanism

Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

Roflumilast Cream (ARQ-151) 0.15% and 0.3% Improved Burden of Signs and Symptoms in Adults With Chronic Plaque Psoriasis in a Phase 2b Study

Roflumilast Cream (ARQ-151) Improved Itch Severity and Itch-Related Sleep Loss in Adults With Chronic Plaque Psoriasis in a Phase 2b Study

Matrilysin expression and function in airway epithelium

Role of Matrix Metalloproteinases and Their Inhibition in Cutaneous Wound Healing and Allergic Contact Hypersensitivity

Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

Expression of 92-kDa Type IV Collagenase mRNA by Eosinophils Associated with Basal Cell Carcinoma

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