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ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

Science (American Association for the Advancement of Science), 2010-06, Vol.328 (5986), p.1689-1693

2010

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Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis

Circulation (New York, N.Y.), 2018-08, Vol.138 (9), p.898-912

2018

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Genetics and Other Omics in Pediatric Pulmonary Arterial Hypertension

Chest, 2020-05, Vol.157 (5), p.1287-1295

2020

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FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis

Cell metabolism, 2012-03, Vol.15 (3), p.372-381

2012

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Proatherogenic Abnormalities of Lipid Metabolism in SirT1 Transgenic Mice Are Mediated through Creb Deacetylation

Cell metabolism, 2011-12, Vol.14 (6), p.758-767

2011

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Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice

Arteriosclerosis, thrombosis, and vascular biology, 2016-07, Vol.36 (7), p.1328

2016

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Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia

Cell metabolism, 2012-01, Vol.15 (1), p.65-74

2012

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Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

Nature medicine, 2013-05, Vol.19 (5), p.586-594

2013

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Genetics and Genomics of Pediatric Pulmonary Arterial Hypertension

Genes, 2020-10, Vol.11 (10), p.1213

2020

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Molecular Function and Contribution of TBX4 in Development and Disease

American journal of respiratory and critical care medicine, 2023-04, Vol.207 (7), p.855-864

2023

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First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease

American journal of respiratory and critical care medicine, 2022-12, Vol.206 (12), p.1522-1533

2022

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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2020-06, Vol.141 (24), p.1986-2000

2020

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Genes that drive the pathobiology of pediatric pulmonary arterial hypertension

Pediatric pulmonology, 2021-03, Vol.56 (3), p.614-620

2021

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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

The Journal of clinical investigation, 2011-10, Vol.121 (10), p.4138-4149

2011

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Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

Genome medicine, 2018-07, Vol.10 (1), p.56-56, Article 56

2018

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Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension

Genome medicine, 2019-11, Vol.11 (1), p.69-69, Article 69

2019

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ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis

Circulation research, 2010-06, Vol.106 (12), p.1861-1869

2010

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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3900-3908

2007

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ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet

The Journal of clinical investigation, 2008-11, Vol.118 (11), p.3701-3713

2008

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Channelopathy Genes in Pulmonary Arterial Hypertension

Biomolecules (Basel, Switzerland), 2022-02, Vol.12 (2), p.265

2022

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Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

Circulation research, 2013-05, Vol.112 (11), p.1456-1465

2013

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Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells

Arteriosclerosis, thrombosis, and vascular biology, 2014-02, Vol.34 (2), p.279

2014

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LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis

Circulation research, 2016-09, Vol.119 (6), p.e91-e103

2016

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TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis

Nature (London), 2016-07, Vol.535 (7611), p.303-307

2016

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ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis

Genetics and Other Omics in Pediatric Pulmonary Arterial Hypertension

FoxOs Integrate Pleiotropic Actions of Insulin in Vascular Endothelium to Protect Mice from Atherosclerosis

Proatherogenic Abnormalities of Lipid Metabolism in SirT1 Transgenic Mice Are Mediated through Creb Deacetylation

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice

Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia

Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

Genetics and Genomics of Pediatric Pulmonary Arterial Hypertension

Molecular Function and Contribution of TBX4 in Development and Disease

First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease

Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension

Genes that drive the pathobiology of pediatric pulmonary arterial hypertension

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension

ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet

Channelopathy Genes in Pulmonary Arterial Hypertension

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells

LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis

Biallelic variants of ATP13A3 cause dose-dependent childhood-onset pulmonary arterial hypertension characterised by extreme morbidity and mortality

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