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Limited choice of natural amino acids as mimetics restricts design of protein lysine methylation studies

Nature communications, 2023-07, Vol.14 (1), p.4097-4097, Article 4097

2023

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Development of an epigenetic tetracycline sensor system based on DNA methylation

PloS one, 2020-05, Vol.15 (5), p.e0232701

2020

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The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Nature communications, 2021-02, Vol.12 (1), p.891-891, Article 891

2021

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H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1

Nature communications, 2017-12, Vol.8 (1), p.2057-13, Article 2057

2017

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Structure, Activity and Function of the Suv39h1 and Suv39h2 Protein Lysine Methyltransferases

Life (Basel, Switzerland), 2021-07, Vol.11 (7), p.703

2021

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Mechanistic Insights into the Allosteric Regulation of the Clr4 Protein Lysine Methyltransferase by Autoinhibition and Automethylation

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8832

2020

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Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma

Molecules (Basel, Switzerland), 2021-12, Vol.26 (24), p.7582

2021

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CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation

Nature communications, 2022-12, Vol.13 (1), p.7636-11, Article 7636

2022

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Activity and specificity of the human SUV39H2 protein lysine methyltransferase

Biochimica et biophysica acta, 2015-01, Vol.1849 (1), p.55-63

2015

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Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex

Molecular oncology, 2017-04, Vol.11 (4), p.373-387

2017

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Discovery of NSD2 non-histone substrates and design of a super-substrate

Communications biology, 2024-06, Vol.7 (1), p.707-12

2024

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Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme

Clinical epigenetics, 2015-03, Vol.7 (1), p.36-36, Article 36

2015

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Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays

Journal of visualized experiments, 2014-11 (93), p.e52203-e52203

2014

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Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide

Communications chemistry, 2022-10, Vol.5 (1), p.139-139, Article 139

2022

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Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

Communications biology, 2020-09, Vol.3 (1), p.511-511, Article 511

2020

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Charakterisierung der Substratspezifität von Protein-Methyltransferasen

Biospektrum, 2023-05, Vol.29 (3), p.249-251

2023

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Specificity of the SUV4–20H1 and SUV4–20H2 protein lysine methyltransferases and methylation of novel substrates

Journal of molecular biology, 2016-06, Vol.428 (11), p.2344-2358

2016

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Reversible switching and stability of the epigenetic memory system in bacteria

The FEBS journal, 2023-04, Vol.290 (8), p.2115-2126

2023

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Model‐based robustness and bistability analysis for methylation‐based, epigenetic memory systems

The FEBS journal, 2021-10, Vol.288 (19), p.5692-5707

2021

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Charakterisierung der Substratspezifität von Protein-Methyltransferasen

Biospektrum, 2023-05, Vol.29 (3), p.249-251

2023

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Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism

The Journal of biological chemistry, 2023-10, Vol.299 (10), p.105236-105236, Article 105236

2023

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Recognition of nonproline N-terminal residues by the Pro/N-degron pathway

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14158-14167

2020

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A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin [beta]-cluster genes in the developing brain

Molecular psychiatry, 2021-12, Vol.26 (12), p.7550

2021

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The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104796-104796, Article 104796

2023

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Distinct specificities of the HEMK2 protein methyltransferase in methylation of glutamine and lysine residues

Protein science, 2024-02, Vol.33 (2), p.e4897-n/a

2024

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Limited choice of natural amino acids as mimetics restricts design of protein lysine methylation studies

Development of an epigenetic tetracycline sensor system based on DNA methylation

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1

Structure, Activity and Function of the Suv39h1 and Suv39h2 Protein Lysine Methyltransferases

Mechanistic Insights into the Allosteric Regulation of the Clr4 Protein Lysine Methyltransferase by Autoinhibition and Automethylation

Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma

CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation

Activity and specificity of the human SUV39H2 protein lysine methyltransferase

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex

Discovery of NSD2 non-histone substrates and design of a super-substrate

Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme

Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays

Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

Charakterisierung der Substratspezifität von Protein-Methyltransferasen

Specificity of the SUV4–20H1 and SUV4–20H2 protein lysine methyltransferases and methylation of novel substrates

Reversible switching and stability of the epigenetic memory system in bacteria

Model‐based robustness and bistability analysis for methylation‐based, epigenetic memory systems

Charakterisierung der Substratspezifität von Protein-Methyltransferasen

Methylation of the transcription factor E2F1 by SETD6 regulates SETD6 expression via a positive feedback mechanism

Recognition of nonproline N-terminal residues by the Pro/N-degron pathway

A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin [beta]-cluster genes in the developing brain

The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation

Distinct specificities of the HEMK2 protein methyltransferase in methylation of glutamine and lysine residues

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