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A Fast-Binding, Functionally Reversible, COX‑2 Radiotracer for CNS PET Imaging

ACS central science, 2024-05, Vol.10 (5), p.1105-1114

2024

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Regioselective indium(III) trifluoromethanesulfonate-catalyzed hydrothiolation of non-activated olefins

Chemical communications (Cambridge, England), 2006-01 (3), p.332-334

2006

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Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif

Journal of medicinal chemistry, 2013-02, Vol.56 (4), p.1772-1776

2013

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Chemoenzymatic Synthesis of Uridine Diphosphate-GlcNAc and Uridine Diphosphate-GalNAc Analogs for the Preparation of Unnatural Glycosaminoglycans

Journal of organic chemistry, 2012-02, Vol.77 (3), p.1449-1456

2012

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Oversulfated Chondroitin Sulfate: Impact of a Heparin Impurity, Associated with Adverse Clinical Events, on Low-Molecular-Weight Heparin Preparation

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5498-5501

2008

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Discovery of the First Histone Deacetylase 6/8 Dual Inhibitors

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4816-4820

2013

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A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

ACS medicinal chemistry letters, 2012-12, Vol.3 (12), p.1034-1038

2012

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Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

The Journal of biological chemistry, 2010-10, Vol.285 (44), p.34240-34249

2010

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Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1822-1826

2012

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Functionally Biased D2R Antagonists: Targeting the β‑Arrestin Pathway to Improve Antipsychotic Treatment

ACS chemical biology, 2018-04, Vol.13 (4), p.1038-1047

2018

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Synthesis and Biological Evaluation of Non‐Hydrolyzable 1,2,3‐Triazole‐Linked Sialic Acid Derivatives as Neuraminidase Inhibitors

European Journal of Organic Chemistry, 2009-06, Vol.2009 (16), p.2611-2620

2009

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Unbiased binding assays for discovering small-molecule probes and drugs

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (6), p.1979-1989

2012

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Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T‑Type Calcium Channel Modulators

ACS pharmacology & translational science, 2022-03, Vol.5 (3), p.156-168

2022

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Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

ACS medicinal chemistry letters, 2012-10, Vol.3 (10), p.808-813

2012

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Aluminium Triflate Catalysed Cyclisation of Unsaturated Alcohols: Novel Synthesis of Rose Oxide and Analogues

European Journal of Organic Chemistry, 2009-11, Vol.2009 (33), p.5788-5795

2009

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Therapeutic potential of isoform selective HDAC inhibitors for the treatment of schizophrenia

Future medicinal chemistry, 2013-09, Vol.5 (13), p.1491-1508

2013

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Exploring COX-2 as a biomarker of microglia-dependent neuroinflammation

The Journal of nuclear medicine (1978), 2018-05, Vol.59, p.1628

Weiwer, Michel

2018

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Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

ACS medicinal chemistry letters, 2012-02, Vol.3 (2), p.112-117

2012

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Indium Triflate-Catalysed Addition of Thio Compounds to Camphene: A Novel Route to 2,3,3-Trimethyl-2-thiobicyclo[2.2.1]heptane Derivatives

European Journal of Organic Chemistry, 2007-05, Vol.2007 (15), p.2464-2469

2007

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Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (14), p.5146-5152

2009

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The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases

Current vascular pharmacology, 2008-07, Vol.6 (3), p.204-217

2008

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A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4164-4169

2011

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Unbiased binding assays for discovering small-molecule probes and drugs: The Chemistry Biology Interface

Bioorganic & medicinal chemistry, 2012, Vol.20 (6), p.1979-1989

2012

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A Fast-Binding, Functionally Reversible, COX‑2 Radiotracer for CNS PET Imaging

Regioselective indium(III) trifluoromethanesulfonate-catalyzed hydrothiolation of non-activated olefins

Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif

Chemoenzymatic Synthesis of Uridine Diphosphate-GlcNAc and Uridine Diphosphate-GalNAc Analogs for the Preparation of Unnatural Glycosaminoglycans

Oversulfated Chondroitin Sulfate: Impact of a Heparin Impurity, Associated with Adverse Clinical Events, on Low-Molecular-Weight Heparin Preparation

Discovery of the First Histone Deacetylase 6/8 Dual Inhibitors

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Functionally Biased D2R Antagonists: Targeting the β‑Arrestin Pathway to Improve Antipsychotic Treatment

Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia

Synthesis and Biological Evaluation of Non‐Hydrolyzable 1,2,3‐Triazole‐Linked Sialic Acid Derivatives as Neuraminidase Inhibitors

Unbiased binding assays for discovering small-molecule probes and drugs

Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T‑Type Calcium Channel Modulators

Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

Aluminium Triflate Catalysed Cyclisation of Unsaturated Alcohols: Novel Synthesis of Rose Oxide and Analogues

Therapeutic potential of isoform selective HDAC inhibitors for the treatment of schizophrenia

Exploring COX-2 as a biomarker of microglia-dependent neuroinflammation

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

Indium Triflate-Catalysed Addition of Thio Compounds to Camphene: A Novel Route to 2,3,3-Trimethyl-2-thiobicyclo[2.2.1]heptane Derivatives

Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols

The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases

A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold

Unbiased binding assays for discovering small-molecule probes and drugs: The Chemistry Biology Interface

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