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Endogenous Angiogenesis Inhibitor Blocks Tumor Growth via Direct and Indirect Effects on Tumor Microenvironment

The American journal of pathology, 2011-11, Vol.179 (5), p.2589-2600

2011

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TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells

Oncotarget, 2013-01, Vol.4 (1), p.166-173

2013

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Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity

iScience, 2018-03, Vol.1, p.87-96

2018

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Shp-1 Mediates the Antiproliferative Activity of Tissue Inhibitor of Metalloproteinase-2 in Human Microvascular Endothelial Cells

The Journal of biological chemistry, 2006-02, Vol.281 (6), p.3711-3721

2006

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Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK

Cancer research (Chicago, Ill.), 2004-12, Vol.64 (24), p.9062-9069

2004

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Tissue Inhibitor of Metalloprotease‑2 (TIMP-2): Bioprocess Development, Physicochemical, Biochemical, and Biological Characterization of Highly Expressed Recombinant Protein

Biochemistry (Easton), 2017-12, Vol.56 (49), p.6423-6433

2017

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Abstract 168: Loss of function mutation in TIMP2 gene accelerates tumorigenesis and mortality in murine model of lung cancer through EGFR signaling

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.168-168

2017

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Preclinical Development of Recombinant Human Tissue Inhibitor of Metalloprotease‐2 as a Novel Biologic Therapy for Cancer

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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Loss of function mutation in TIMP2 gene accelerates tumorigenesis and mortality in murine model of lung cancer through EGFR signaling

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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TIMP‐2 Inhibits Tumor Growth in Murine Model of Lung Cancer through EGFR signaling

The FASEB journal, 2018-04, Vol.32 (S1), p.281.9-281.9

2018

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Abstract 676: Tissue inhibitor of metalloproteinase-2 (TIMP2) deficiency enhances tumor burden via increasing HIF-2á expression

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.676-676

2016

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Abstract 676: Tissue inhibitor of metalloproteinase-2 (TIMP2) deficiency enhances tumor burden via increasing HIF-2 expression

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.676-676

2016

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Pre‐clinical Development of rhTIMP‐2 as a Novel Anti‐Cancer Therapeutic

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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TIMP‐2 Deficiency Alters Host Immune Response in Murine Lung Tumor Microenvironment

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Recombinant human Tissue Inhibitor of Metalloprotease −2; a novel anti‐cancer therapeutic

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Vascular injury induces posttranscriptional regulation of the Id3 gene: cloning of a novel Id3 isoform expressed during vascular lesion formation in rat and human atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2001-05, Vol.21 (5), p.752-758

2001

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Abstract B79: TIMP-2 mediated growth inhibition of human glioma U87MG is accompanied by elevated IGFBP7 and FSP-1/S100A4 expression at the tumor/stroma interface

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (1_Supplement), p.B79-B79

2015

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TIMP-2 targets tumor-associated myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesis

Journal of immunotherapy (1997), 2012-07, Vol.35 (6), p.502-512

2012

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Isolation and characterization of novel RECK tumor suppressor gene splice variants

Oncotarget, 2015-10, Vol.6 (32), p.33120-33133

2015

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Characterization of an E-box-dependent cis element in the smooth muscle alpha-actin promoter

Arteriosclerosis, thrombosis, and vascular biology, 1999-11, Vol.19 (11), p.2591-2599

1999

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TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118

Oncogene, 2006-07, Vol.25 (30), p.4230-4234

2006

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Abstract LB-332: A novel TIMP-2-mediated cytoplasmic mechanism for the regulation of receptor tyrosine kinase, VEGFR-2

Cancer research (Chicago, Ill.), 2008-05, Vol.68 (9_Supplement), p.LB-332-LB-332

2008

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Alveolar epithelial cell chemokine expression triggered by antigen-specific cytolytic CD8(+) T cell recognition

The Journal of clinical investigation, 2000-09, Vol.106 (6), p.R49-R58

2000

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TIMP-2 promotes cell spreading and adhesion via upregulation of Rap1 signaling

Biochemical and biophysical research communications, 2006-07, Vol.345 (3), p.1201-1206

2006

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Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells

The Journal of biological chemistry, 2005-12, Vol.281 (6), p.3711-3721

2005

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Endogenous Angiogenesis Inhibitor Blocks Tumor Growth via Direct and Indirect Effects on Tumor Microenvironment

TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells

Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity

Shp-1 Mediates the Antiproliferative Activity of Tissue Inhibitor of Metalloproteinase-2 in Human Microvascular Endothelial Cells

Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK

Tissue Inhibitor of Metalloprotease‑2 (TIMP-2): Bioprocess Development, Physicochemical, Biochemical, and Biological Characterization of Highly Expressed Recombinant Protein

Abstract 168: Loss of function mutation in TIMP2 gene accelerates tumorigenesis and mortality in murine model of lung cancer through EGFR signaling

Preclinical Development of Recombinant Human Tissue Inhibitor of Metalloprotease‐2 as a Novel Biologic Therapy for Cancer

Loss of function mutation in TIMP2 gene accelerates tumorigenesis and mortality in murine model of lung cancer through EGFR signaling

TIMP‐2 Inhibits Tumor Growth in Murine Model of Lung Cancer through EGFR signaling

Abstract 676: Tissue inhibitor of metalloproteinase-2 (TIMP2) deficiency enhances tumor burden via increasing HIF-2á expression

Abstract 676: Tissue inhibitor of metalloproteinase-2 (TIMP2) deficiency enhances tumor burden via increasing HIF-2 expression

Pre‐clinical Development of rhTIMP‐2 as a Novel Anti‐Cancer Therapeutic

TIMP‐2 Deficiency Alters Host Immune Response in Murine Lung Tumor Microenvironment

Recombinant human Tissue Inhibitor of Metalloprotease −2; a novel anti‐cancer therapeutic

Vascular injury induces posttranscriptional regulation of the Id3 gene: cloning of a novel Id3 isoform expressed during vascular lesion formation in rat and human atherosclerosis

Abstract B79: TIMP-2 mediated growth inhibition of human glioma U87MG is accompanied by elevated IGFBP7 and FSP-1/S100A4 expression at the tumor/stroma interface

TIMP-2 targets tumor-associated myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesis

Isolation and characterization of novel RECK tumor suppressor gene splice variants

Characterization of an E-box-dependent cis element in the smooth muscle alpha-actin promoter

TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118

Abstract LB-332: A novel TIMP-2-mediated cytoplasmic mechanism for the regulation of receptor tyrosine kinase, VEGFR-2

Alveolar epithelial cell chemokine expression triggered by antigen-specific cytolytic CD8(+) T cell recognition

TIMP-2 promotes cell spreading and adhesion via upregulation of Rap1 signaling

Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells

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