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NPTX2 and cognitive dysfunction in Alzheimer's Disease

eLife, 2017-03, Vol.6

2017

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The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

Acta neuropathologica, 2010-06, Vol.119 (6), p.755-770

2010

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Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)

Archives of biochemistry and biophysics, 2011-03, Vol.507 (2), p.212-218

2011

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Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease

Neurobiology of aging, 2004-05, Vol.25 (5), p.663-674

2004

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Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Acta neuropathologica communications, 2018-12, Vol.6 (1), p.143-143, Article 143

2018

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Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

The FASEB journal, 2008-09, Vol.22 (9), p.3224-3233

2008

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Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

Genome Biology, 2015-11, Vol.16 (1), p.263-263, Article 263

2015

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Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome

Acta neuropathologica communications, 2022-01, Vol.10 (1), p.2-2, Article 2

2022

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Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28660-28669

2008

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Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism

Acta neuropathologica communications, 2020-04, Vol.8 (1), p.58-58, Article 58

2020

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Characterization of placental and decidual cell development in early pregnancy loss by single-cell RNA sequencing

Cell & bioscience, 2022-10, Vol.12 (1), p.1-168, Article 168

2022

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Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

Acta neuropathologica communications, 2022-09, Vol.10 (1), p.132-132, Article 132

2022

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Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism

Brain research, 2013-05, Vol.1512, p.106-122

2013

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Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism

Acta neuropathologica communications, 2014-03, Vol.2 (1), p.28-28, Article 28

2014

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Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

PloS one, 2012-05, Vol.7 (5), p.e35414-e35414

2012

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Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection

Acta neuropathologica, 2014-02, Vol.127 (2), p.243-256

2014

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The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

Acta neuropathologica, 2008-10, Vol.116 (4), p.391-407

2008

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Effect of trichostatin A on gelsolin levels, proteolysis of amyloid precursor protein, and amyloid beta-protein load in the brain of transgenic mouse model of Alzheimer's disease

Current Alzheimer research, 2014-12, Vol.11 (10), p.1002

2014

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Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)

Journal of neuroscience research, 2014-02, Vol.92 (2), p.162-173

2014

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Dystrophic Serotonin Axons in Postmortem Brains from Young Autism Patients

Anatomical record (Hoboken, N.J. : 2007), 2011-10, Vol.294 (10), p.1653-1662

2011

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Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice

Journal of neuroscience research, 2012-05, Vol.90 (5), p.999-1010

2012

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Mild cognitive impairment (MCI): a historical perspective

International psychogeriatrics, 2008-02, Vol.20 (1), p.18-31

2008

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High-affinity rabbit monoclonal antibodies specific for amyloid peptides amyloid-β40 and amyloid-β42

Journal of Alzheimer's disease, 2011, Vol.23 (2), p.293

2011

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Kinetic Properties of a MNB/DYRK1A Mutant Suitable for the Elucidation of Biochemical Pathways

Biochemistry (Easton), 2006-10, Vol.45 (39), p.12011-12019

2006

Volltextzugriff (PDF)

Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder

Autism research, 2024-07, Vol.17 (7), p.1300-1321

2024

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NPTX2 and cognitive dysfunction in Alzheimer's Disease

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)

Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease

Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome

Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome

Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism

Characterization of placental and decidual cell development in early pregnancy loss by single-cell RNA sequencing

Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism

Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism

Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

Effect of trichostatin A on gelsolin levels, proteolysis of amyloid precursor protein, and amyloid beta-protein load in the brain of transgenic mouse model of Alzheimer's disease

Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)

Dystrophic Serotonin Axons in Postmortem Brains from Young Autism Patients

Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice

Mild cognitive impairment (MCI): a historical perspective

High-affinity rabbit monoclonal antibodies specific for amyloid peptides amyloid-β40 and amyloid-β42

Kinetic Properties of a MNB/DYRK1A Mutant Suitable for the Elucidation of Biochemical Pathways

Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder

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