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Questioning coverage values determined by 2D western blots: A critical study on the characterization of anti‐HCP ELISA reagents

Biotechnology and bioengineering, 2021-03, Vol.118 (3), p.1116-1126

2021

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Toward optimal clearance: A universal affinity‐based mass spectrometry approach for comprehensive ELISA reagent coverage evaluation and HCP hitchhiker analysis

Biotechnology progress, 2022-05, Vol.38 (3), p.e3244-n/a

2022

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Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry

mAbs, 2016-01, Vol.8 (2), p.331-339

2016

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The ATPase Cycle of the Mitochondrial Hsp90 Analog Trap1

The Journal of biological chemistry, 2008-04, Vol.283 (17), p.11677-11688

2008

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Hsp90 Regulates the Activity of Wild Type p53 under Physiological and Elevated Temperatures

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.48846-48854

2004

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Substrate Transfer from the Chaperone Hsp70 to Hsp90

Journal of molecular biology, 2006-02, Vol.356 (3), p.802-811

2006

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Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing

PloS one, 2013-11, Vol.8 (11), p.e81639-e81639

2013

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The Yeast Hsp110 Sse1 Functionally Interacts with the Hsp70 Chaperones Ssa and Ssb

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41262-41269

2005

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Sti1 Is a Novel Activator of the Ssa Proteins

The Journal of biological chemistry, 2003-07, Vol.278 (28), p.25970-25976

2003

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The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange

Antibodies (Basel), 2019-10, Vol.8 (4), p.49

2019

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Evaluation of Peptide Fractionation and Native Digestion as Two Novel Sample Preparation Workflows to Improve HCP Characterization by LC–MS/MS

Analytical chemistry (Washington), 2019-08, Vol.91 (15), p.9716-9723

2019

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Cns1 Is an Activator of the Ssa1 ATPase Activity

The Journal of biological chemistry, 2004-05, Vol.279 (22), p.23267-23273

2004

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Dissection of the Contribution of Individual Domains to the ATPase Mechanism of Hsp90

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.39303-39310

2003

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Recent advances in LC–MS based characterization of protein-based bio-therapeutics – mastering analytical challenges posed by the increasing format complexity

Journal of pharmaceutical and biomedical analysis, 2020-07, Vol.186, p.113251-113251, Article 113251

2020

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Fast and Automated Characterization of Antibody Variants with 4D HPLC/MS

Analytical chemistry (Washington), 2018-02, Vol.90 (3), p.2119-2125

2018

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The agony of choice: Impact of the host animal species on the enzyme‐linked immunosorbent assay performance for host cell protein quantification

Biotechnology and bioengineering, 2023-01, Vol.120 (1), p.184-193

2023

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Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles

Electrophoresis, 2017-12, Vol.38 (24), p.3136-3146

2017

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A fast and sensitive high-throughput assay to assess polysorbate-degrading hydrolytic activity in biopharmaceuticals

European journal of pharmaceutics and biopharmaceutics, 2023-06, Vol.187, p.120-129

2023

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Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2021-08, Vol.32 (8), p.2062-2071

2021

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Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry

Analytical chemistry (Washington), 2023-01, Vol.95 (4), p.2203-2212

2023

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Oxidation of M252 but not M428 in hu-IgG1 is responsible for decreased binding to and activation of hu-FcγRIIa (His131)

Biologicals, 2017-11, Vol.50, p.125-128

2017

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phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90

The EMBO journal, 2006-01, Vol.25 (2), p.367-376

2006

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Trends in Process Analytical Technology: Present State in Bioprocessing

New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins, 2018, Vol.165, p.211-252

2018

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Functional assessment of antibody oxidation by native mass spectrometry

mAbs, 2015-09, Vol.7 (5), p.891-900

2015

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Getting CHO host cell protein analysis up to speed

Pharmaceutical bioprocessing, 2015-02, Vol.3 (1), p.13-23

2015

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Questioning coverage values determined by 2D western blots: A critical study on the characterization of anti‐HCP ELISA reagents

Toward optimal clearance: A universal affinity‐based mass spectrometry approach for comprehensive ELISA reagent coverage evaluation and HCP hitchhiker analysis

Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry

The ATPase Cycle of the Mitochondrial Hsp90 Analog Trap1

Hsp90 Regulates the Activity of Wild Type p53 under Physiological and Elevated Temperatures

Substrate Transfer from the Chaperone Hsp70 to Hsp90

Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing

The Yeast Hsp110 Sse1 Functionally Interacts with the Hsp70 Chaperones Ssa and Ssb

Sti1 Is a Novel Activator of the Ssa Proteins

The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange

Evaluation of Peptide Fractionation and Native Digestion as Two Novel Sample Preparation Workflows to Improve HCP Characterization by LC–MS/MS

Cns1 Is an Activator of the Ssa1 ATPase Activity

Dissection of the Contribution of Individual Domains to the ATPase Mechanism of Hsp90

Recent advances in LC–MS based characterization of protein-based bio-therapeutics – mastering analytical challenges posed by the increasing format complexity

Fast and Automated Characterization of Antibody Variants with 4D HPLC/MS

The agony of choice: Impact of the host animal species on the enzyme‐linked immunosorbent assay performance for host cell protein quantification

Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles

A fast and sensitive high-throughput assay to assess polysorbate-degrading hydrolytic activity in biopharmaceuticals

Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry

Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry

Oxidation of M252 but not M428 in hu-IgG1 is responsible for decreased binding to and activation of hu-FcγRIIa (His131)

phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90

Trends in Process Analytical Technology: Present State in Bioprocessing

Functional assessment of antibody oxidation by native mass spectrometry

Getting CHO host cell protein analysis up to speed

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