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A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

Nature communications, 2022-01, Vol.13 (1), p.199-199, Article 199

2022

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RNA target highlights in CASP15: Evaluation of predicted models by structure providers

Proteins, structure, function, and bioinformatics, 2023-12, Vol.91 (12), p.1600-1615

2023

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A riboswitch separated from its ribosome-binding site still regulates translation

Nucleic acids research, 2023-03, Vol.51 (5), p.2464

2023

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RNA in the Loop: Probing T-loop/T-loop Receptor Interactions as Mediators of Long-range RNA Contacts that Influence Gene Regulation

Journal of molecular biology, 2023-05, Vol.435 (10), p.168087-168087, Article 168087

Wedekind, Joseph E.

2023

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Structural analysis of a class III preQ₁ riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.E3485-E3494

2015

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The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11012-11016

2009

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Nucleobase mutants of a bacterial preQ1-II riboswitch that uncouple metabolite sensing from gene regulation

The Journal of biological chemistry, 2020-02, Vol.295 (9), p.2555-2567

2020

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Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery

The Journal of biological chemistry, 2019-06, Vol.294 (24), p.9326-9341

2019

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Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing

Crystals (Basel), 2021-03, Vol.11 (3), p.273

2021

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A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis

Journal of the American Chemical Society, 2012-10, Vol.134 (41), p.16933-16936

2012

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Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

The Journal of biological chemistry, 2023-10, Vol.299 (10), p.105208-105208, Article 105208

2023

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Full-Length NAD + -I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate

Biochemistry (Easton), 2023-12, Vol.62 (23), p.3396-3410

2023

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Arginine Forks Are a Widespread Motif to Recognize Phosphate Backbones and Guanine Nucleobases in the RNA Major Groove

Journal of the American Chemical Society, 2020-11, Vol.142 (47), p.19835-19839

2020

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Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold

Nature chemical biology, 2013-06, Vol.9 (6), p.353

2013

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APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain

The Journal of biological chemistry, 2008-11, Vol.283 (48), p.33329-33336

2008

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Nanostructures of APOBEC3G Support a Hierarchical Assembly Model of High Molecular Mass Ribonucleoprotein Particles from Dimeric Subunits

The Journal of biological chemistry, 2006-12, Vol.281 (50), p.38122-38126

2006

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Direct Raman measurement of an elevated base pKa in the active site of a small ribozyme in a precatalytic conformation

Journal of the American Chemical Society, 2009-09, Vol.131 (36), p.12908-12909

2009

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Nuclear Exclusion of the HIV-1 Host Defense Factor APOBEC3G Requires a Novel Cytoplasmic Retention Signal and Is Not Dependent on RNA Binding

The Journal of biological chemistry, 2008-03, Vol.283 (12), p.7320-7327

2008

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Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes

The Journal of biological chemistry, 2017-06, Vol.292 (23), p.9441-9450

2017

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Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors

The Journal of biological chemistry, 2020-12, Vol.295 (49), p.16470-16486

2020

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Coupling Green Fluorescent Protein Expression with Chemical Modification to Probe Functionally Relevant Riboswitch Conformations in Live Bacteria

Biochemistry (Easton), 2018-08, Vol.57 (31), p.4620-4628

2018

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Isothermal Titration Calorimetry Analysis of a Cooperative Riboswitch Using an Interdependent-Sites Binding Model

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2568, p.53

2023

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Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells

The Journal of biological chemistry, 2021-12, Vol.297 (6), p.101390-101390, Article 101390

2021

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Comparison of a PreQ1 Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation

The Journal of biological chemistry, 2011-07, Vol.286 (28), p.24626-24637

2011

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Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation

Nucleic acids research, 2020-08, Vol.48 (14), p.8146

2020

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A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

RNA target highlights in CASP15: Evaluation of predicted models by structure providers

A riboswitch separated from its ribosome-binding site still regulates translation

RNA in the Loop: Probing T-loop/T-loop Receptor Interactions as Mediators of Long-range RNA Contacts that Influence Gene Regulation

Structural analysis of a class III preQ₁ riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain

Nucleobase mutants of a bacterial preQ1-II riboswitch that uncouple metabolite sensing from gene regulation

Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery

Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing

A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis

Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

Full-Length NAD + -I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate

Arginine Forks Are a Widespread Motif to Recognize Phosphate Backbones and Guanine Nucleobases in the RNA Major Groove

Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold

APOBEC3G Subunits Self-associate via the C-terminal Deaminase Domain

Nanostructures of APOBEC3G Support a Hierarchical Assembly Model of High Molecular Mass Ribonucleoprotein Particles from Dimeric Subunits

Direct Raman measurement of an elevated base pKa in the active site of a small ribozyme in a precatalytic conformation

Nuclear Exclusion of the HIV-1 Host Defense Factor APOBEC3G Requires a Novel Cytoplasmic Retention Signal and Is Not Dependent on RNA Binding

Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes

Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors

Coupling Green Fluorescent Protein Expression with Chemical Modification to Probe Functionally Relevant Riboswitch Conformations in Live Bacteria

Isothermal Titration Calorimetry Analysis of a Cooperative Riboswitch Using an Interdependent-Sites Binding Model

Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells

Comparison of a PreQ1 Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation

Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation

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