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Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Frontiers in pharmacology, 2019-09, Vol.10, p.1047-1047

2019

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Hsp90 activator Aha1 drives production of pathological tau aggregates

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (36), p.9707-9712

2017

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Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

International journal of molecular sciences, 2020-07, Vol.21 (15), p.5442

2020

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Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma

Scientific reports, 2017-12, Vol.7 (1), p.17951-9, Article 17951

2017

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Potent Inhibition of Huntingtin Aggregation and Cytotoxicity by a Disulfide Bond-Free Single-Domain Intracellular Antibody

Proceedings of the National Academy of Sciences - PNAS, 2004-12, Vol.101 (51), p.17616-17621

2004

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Suppression of Huntington's Disease Pathology in Drosophila by Human Single-Chain Fv Antibodies

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (32), p.11563-11568

2005

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Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation

ACS chemical biology, 2023-05, Vol.18 (5), p.1124-1135

2023

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Inositol 1,4,5-Trisphosphate Receptor Ubiquitination Is Mediated by Mammalian Ubc7, a Component of the Endoplasmic Reticulum-associated Degradation Pathway, and Is Inhibited by Chelation of Intracellular Zn2

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38238-38246

2003

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Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor

Molecular cancer therapeutics, 2004-10, Vol.3 (10), p.1263-1269

2004

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18F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models

The Journal of nuclear medicine (1978), 2017-03, Vol.58 (3), p.367-373

2017

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18 F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models

Journal of Nuclear Medicine, 2017-03, Vol.58 (3), p.367-373

2017

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A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x(C)⁻ transporter

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (23), p.5512-5515

2014

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Engineered Two-Helix Small Proteins for Molecular Recognition

Chembiochem : a European journal of chemical biology, 2009-05, Vol.10 (8), p.1293-1296

2009

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Development of a Human Light Chain Variable Domain (V L) Intracellular Antibody Specific for the Amino Terminus of Huntingtin via Yeast Surface Display

Journal of molecular biology, 2004-09, Vol.342 (3), p.901-912

2004

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Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid

The Journal of nuclear medicine (1978), 2014-04, Vol.55 (4), p.657-664

2014

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In vivo targeting of HER2-positive tumor using 2-helix affibody molecules

Amino acids, 2012-07, Vol.43 (1), p.405-413

2012

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A novel 18F-labeled two-helix scaffold protein for PET imaging of HER2-positive tumor

European journal of nuclear medicine and molecular imaging, 2011-11, Vol.38 (11), p.1977-1984

2011

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Ubiquitination and Proteasomal Degradation of Endogenous and Exogenous Inositol 1,4,5-Trisphosphate Receptors in αT3-1 Anterior Pituitary Cells

The Journal of biological chemistry, 2003-01, Vol.278 (2), p.940-947

2003

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A 2-Helix Small Protein Labeled with 68Ga for PET Imaging of HER2 Expression

The Journal of nuclear medicine (1978), 2009-09, Vol.50 (9), p.1492-1499

2009

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64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors

Molecular imaging and biology, 2010-06, Vol.12 (3), p.316-324

2010

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N, N, N′, N′-Tetrakis(2-pyridylmethyl)ethylenediamine inhibits ligand binding to certain G protein-coupled receptors

European journal of pharmacology, 2003-08, Vol.474 (1), p.1-5

2003

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A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the xC− transporter

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (23), p.5512-5515

2014

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A simple route to [ super(11)C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x sub(C) super(-) transporter

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (23), p.5512-5515

2014

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Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, ^sup 18^F-5-Fluoro-L-Aminosuberic Acid

The Journal of nuclear medicine (1978), 2014-04, Vol.55 (4), p.657

2014

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Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, sigma up 18 Theta -5-Fluoro-L-Aminosuberic Acid

The Journal of nuclear medicine (1978), 2014-04, Vol.55 (4), p.657-657

2014

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Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Hsp90 activator Aha1 drives production of pathological tau aggregates

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma

Potent Inhibition of Huntingtin Aggregation and Cytotoxicity by a Disulfide Bond-Free Single-Domain Intracellular Antibody

Suppression of Huntington's Disease Pathology in Drosophila by Human Single-Chain Fv Antibodies

Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation

Inositol 1,4,5-Trisphosphate Receptor Ubiquitination Is Mediated by Mammalian Ubc7, a Component of the Endoplasmic Reticulum-associated Degradation Pathway, and Is Inhibited by Chelation of Intracellular Zn2

Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor

18F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models

18 F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models

A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x(C)⁻ transporter

Engineered Two-Helix Small Proteins for Molecular Recognition

Development of a Human Light Chain Variable Domain (V L) Intracellular Antibody Specific for the Amino Terminus of Huntingtin via Yeast Surface Display

Functional imaging of oxidative stress with a novel PET imaging agent, 18F-5-fluoro-L-aminosuberic acid

In vivo targeting of HER2-positive tumor using 2-helix affibody molecules

A novel 18F-labeled two-helix scaffold protein for PET imaging of HER2-positive tumor

Ubiquitination and Proteasomal Degradation of Endogenous and Exogenous Inositol 1,4,5-Trisphosphate Receptors in αT3-1 Anterior Pituitary Cells

A 2-Helix Small Protein Labeled with 68Ga for PET Imaging of HER2 Expression

64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors

N, N, N′, N′-Tetrakis(2-pyridylmethyl)ethylenediamine inhibits ligand binding to certain G protein-coupled receptors

A simple route to [11C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the xC− transporter

A simple route to [ super(11)C]N-Me labeling of aminosuberic acid for proof of feasibility imaging of the x sub(C) super(-) transporter

Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, ^sup 18^F-5-Fluoro-L-Aminosuberic Acid

Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, sigma up 18 Theta -5-Fluoro-L-Aminosuberic Acid

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