UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Chemical communications (Cambridge, England), 2022-10, Vol.58 (84), p.11762-11782

2022

Volltextzugriff (PDF)

Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone

Biochemical and biophysical research communications, 2020-12, Vol.533 (3), p.553-558

2020

Volltextzugriff (PDF)

L’appel de l’étranger : Traduire en langue française en 1886

2015

Volltextzugriff (PDF)

HIV Protease: Historical Perspective and Current Research

Viruses, 2021-05, Vol.13 (5), p.839

2021

Volltextzugriff (PDF)

Evolution of drug resistance in HIV protease

BMC bioinformatics, 2020-12, Vol.21 (Suppl 18), p.497-497, Article 497

2020

Volltextzugriff (PDF)

Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

PloS one, 2016-12, Vol.11 (12), p.e0168616-e0168616

2016

Volltextzugriff (PDF)

Enhancing Protein Backbone Binding-A Fruitful Concept for Combating Drug-Resistant HIV

Angewandte Chemie International Edition, 2012-02, Vol.51 (8), p.1778-1802

International ed. in English, 2012

Volltextzugriff (PDF)

Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4867-4879

2020

Volltextzugriff (PDF)

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase

Archives of biochemistry and biophysics, 2022-01, Vol.715 (C), p.109100-109100, Article 109100

2022

Volltextzugriff (PDF)

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Accounts of chemical research, 2008-01, Vol.41 (1), p.78-86

2008

Volltextzugriff (PDF)

Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20

Biochemical and biophysical research communications, 2019-10, Vol.519 (1), p.61-66

2019

Volltextzugriff (PDF)

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Bioorganic & medicinal chemistry letters, 2023-03, Vol.83 (C), p.129168-129168, Article 129168

2023

Volltextzugriff (PDF)

Analysis of drug resistance in HIV protease

BMC bioinformatics, 2018-10, Vol.19 (Suppl 11), p.362-362, Article 362

2018

Volltextzugriff (PDF)

HIV-1 Protease: Structural Perspectives on Drug Resistance

Viruses, 2009-12, Vol.1 (3), p.1110-1136

2009

Volltextzugriff (PDF)

Design and Synthesis of Potent HIV‑1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure–Activity Studies and Biological and X‑ray Structural Studies

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9722-9737

2018

Volltextzugriff (PDF)

Automated prediction of HIV drug resistance from genotype data

BMC bioinformatics, 2016-08, Vol.17 Suppl 8 (Suppl 8), p.278, Article 278

2016

Volltextzugriff (PDF)

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Angewandte Chemie (International ed.), 2016-04, Vol.55 (16), p.4924-4927

International ed. in English, 2016

Volltextzugriff (PDF)

Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.2018-2025

2017

Volltextzugriff (PDF)

Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (22), p.9072-9077

2011

Volltextzugriff (PDF)

Potent HIV‐1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein‐Ligand X‐ray Structural Studies

ChemMedChem, 2019-11, Vol.14 (21), p.1863-1872

2019

Volltextzugriff (PDF)

Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands

ChemMedChem, 2022-05, Vol.17 (9), p.e202200058-n/a

2022

Volltextzugriff (PDF)

Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (21), p.4925-4931

2017

Volltextzugriff (PDF)

Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV‑1 Protease Inhibitors: Design, Synthesis, Protein X‑ray Structural Studies, and Biological Evaluation

Journal of medicinal chemistry, 2016-07, Vol.59 (14), p.6826-6837

2016

Volltextzugriff (PDF)

Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands

European journal of medicinal chemistry, 2018-12, Vol.160 (C), p.171-182

2018

Volltextzugriff (PDF)

Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex

Bioorganic & medicinal chemistry, 2017-10, Vol.25 (19), p.5114-5127

2017

Volltextzugriff (PDF)

1 – 25 von 326

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(293)
Mit Volltextzugriff
(293)

Publikationsform

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(233)
Life Sciences & Biomedicine
(207)
Biochemistry & Molecular Biology
(126)
Humans
(124)
Models, Molecular
(113)
Crystallography, X-Ray
(93)
Hiv Protease - Chemistry
(79)
Hiv Protease - Metabolism
(77)
Binding Sites
(68)
Protein Conformation
(67)
Hiv Protease Inhibitors - Pharmacology
(66)
Molecular Sequence Data
(66)
Amino Acid Sequence
(65)
Hiv Protease Inhibitors - Chemistry
(55)
Hiv Protease - Genetics
(53)
Hiv-1 - Enzymology
(51)
Biological And Medical Sciences
(50)
Pharmacology & Pharmacy
(47)
Kinetics
(46)
Chemistry, Medicinal
(44)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone

L’appel de l’étranger : Traduire en langue française en 1886

HIV Protease: Historical Perspective and Current Research

Evolution of drug resistance in HIV protease

Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

Enhancing Protein Backbone Binding-A Fruitful Concept for Combating Drug-Resistant HIV

Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Analysis of drug resistance in HIV protease

HIV-1 Protease: Structural Perspectives on Drug Resistance

Design and Synthesis of Potent HIV‑1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure–Activity Studies and Biological and X‑ray Structural Studies

Automated prediction of HIV drug resistance from genotype data

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Inhibition of autoprocessing of natural variants and multidrug resistant mutant precursors of HIV-1 protease by clinical inhibitors

Potent HIV‐1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein‐Ligand X‐ray Structural Studies

Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands

Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands

Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV‑1 Protease Inhibitors: Design, Synthesis, Protein X‑ray Structural Studies, and Biological Evaluation

Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands

Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex

Suchergebnisse filtern