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VBA für Office-Automatisierung und Digitalisierung

Weber, Irene

2024th edition, 2024

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Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Chemical communications (Cambridge, England), 2022-10, Vol.58 (84), p.11762-11782

2022

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Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone

Biochemical and biophysical research communications, 2020-12, Vol.533 (3), p.553-558

2020

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Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

PloS one, 2016-12, Vol.11 (12), p.e0168616-e0168616

2016

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HIV Protease: Historical Perspective and Current Research

Viruses, 2021-05, Vol.13 (5), p.839

2021

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Evolution of drug resistance in HIV protease

BMC bioinformatics, 2020-12, Vol.21 (Suppl 18), p.497-497, Article 497

2020

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Enhancing Protein Backbone Binding-A Fruitful Concept for Combating Drug-Resistant HIV

Angewandte Chemie International Edition, 2012-02, Vol.51 (8), p.1778-1802

International ed. in English, 2012

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Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Angewandte Chemie (International ed.), 2016-04, Vol.55 (16), p.4924-4927

International ed. in English, 2016

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Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PRS17

Biochemical and biophysical research communications, 2021-08, Vol.566, p.30-35

2021

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Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4867-4879

2020

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Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase

Archives of biochemistry and biophysics, 2022-01, Vol.715 (C), p.109100-109100, Article 109100

2022

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Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Accounts of chemical research, 2008-01, Vol.41 (1), p.78-86

2008

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Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20

Biochemical and biophysical research communications, 2019-10, Vol.519 (1), p.61-66

2019

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Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Bioorganic & medicinal chemistry letters, 2023-03, Vol.83 (C), p.129168-129168, Article 129168

2023

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Analysis of drug resistance in HIV protease

BMC bioinformatics, 2018-10, Vol.19 (Suppl 11), p.362-362, Article 362

2018

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HIV-1 Protease: Structural Perspectives on Drug Resistance

Viruses, 2009-12, Vol.1 (3), p.1110-1136

2009

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Design and Synthesis of Potent HIV‑1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure–Activity Studies and Biological and X‑ray Structural Studies

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9722-9737

2018

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Automated prediction of HIV drug resistance from genotype data

BMC bioinformatics, 2016-08, Vol.17 Suppl 8 (Suppl 8), p.278, Article 278

2016

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Highly drug‐resistant HIV‐1 protease reveals decreased intra‐subunit interactions due to clusters of mutations

The FEBS journal, 2020-08, Vol.287 (15), p.3235-3254

2020

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Design and Development of Highly Potent HIV‑1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Journal of medicinal chemistry, 2017-05, Vol.60 (10), p.4267-4278

2017

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Highly resistant HIV-1 proteases and strategies for their inhibition

Future medicinal chemistry, 2015-06, Vol.7 (8), p.1023-1038

2015

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Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Journal of medicinal chemistry, 2017-03, Vol.60 (5), p.2018-2025

2017

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Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies

Organic & biomolecular chemistry, 2024-09, Vol.22 (36), p.7354-7372

2024

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Structural studies of antiviral inhibitor with HIV-1 protease bearing drug resistant substitutions of V32I, I47V and V82I

Biochemical and biophysical research communications, 2019-06, Vol.514 (3), p.974-978

2019

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HIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural Rearrangements

Biochemistry (Easton), 2012-04, Vol.51 (13), p.2819-2828

2012

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VBA für Office-Automatisierung und Digitalisierung

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone

Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics

HIV Protease: Historical Perspective and Current Research

Evolution of drug resistance in HIV protease

Enhancing Protein Backbone Binding-A Fruitful Concept for Combating Drug-Resistant HIV

Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site

Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PRS17

Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Analysis of drug resistance in HIV protease

HIV-1 Protease: Structural Perspectives on Drug Resistance

Design and Synthesis of Potent HIV‑1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure–Activity Studies and Biological and X‑ray Structural Studies

Automated prediction of HIV drug resistance from genotype data

Highly drug‐resistant HIV‐1 protease reveals decreased intra‐subunit interactions due to clusters of mutations

Design and Development of Highly Potent HIV‑1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Highly resistant HIV-1 proteases and strategies for their inhibition

Room Temperature Neutron Crystallography of Drug Resistant HIV‑1 Protease Uncovers Limitations of X‑ray Structural Analysis at 100 K

Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies

Structural studies of antiviral inhibitor with HIV-1 protease bearing drug resistant substitutions of V32I, I47V and V82I

HIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural Rearrangements

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