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Discovery of an archetypal protein transport system in bacterial outer membranes

Nature structural & molecular biology, 2012-05, Vol.19 (5), p.506-510

2012

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The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

Cell reports (Cambridge), 2018-05, Vol.23 (9), p.2782-2794

2018

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Dynamic Association of BAM Complex Modules Includes Surface Exposure of the Lipoprotein BamC

Journal of molecular biology, 2012-09, Vol.422 (4), p.545-555

2012

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The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons

mBio, 2021-06, Vol.12 (3), p.e0130221-e0130221

2021

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Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability

eLife, 2022-01, Vol.11

2022

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Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity

eLife, 2024-01, Vol.12

2024

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Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

eLife, 2022-09, Vol.11

2022

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The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp

eLife, 2023-07, Vol.12

2023

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A bioinformatic strategy for the detection, classification and analysis of bacterial autotransporters

PloS one, 2012-08, Vol.7 (8), p.e43245-e43245

2012

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Dissecting EXP2 sequence requirements for protein export in malaria parasites

Frontiers in cellular and infection microbiology, 2023, Vol.13, p.1332146

2023

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Evolution of the β-barrel assembly machinery

Trends in microbiology (Regular ed.), 2012-12, Vol.20 (12), p.612-620

2012

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Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria

Frontiers in cellular and infection microbiology, 2017-05, Vol.7, p.220-220

2017

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Understanding the structure and function of Plasmodium aminopeptidases to facilitate drug discovery

Current opinion in structural biology, 2023-10, Vol.82, p.102693, Article 102693

2023

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Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein

PloS one, 2013-11, Vol.8 (11), p.e79038

2013

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Assembly of β-barrel proteins into bacterial outer membranes

Biochimica et biophysica acta, 2014-08, Vol.1843 (8), p.1542-1550

2014

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Structural and functional requirements for activity of the Tim9-Tim10 complex in mitochondrial protein import

Molecular biology of the cell, 2009-02, Vol.20 (3), p.769-779

2009

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A Small Tim Homohexamer in the Relict Mitochondrion of Cryptosporidium

Molecular biology and evolution, 2012-01, Vol.29 (1), p.113-122

2012

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Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases

Biochemical journal, 2021-07, Vol.478 (13), p.2697-2713

2021

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Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile

Journal of medicinal chemistry, 2024-01, Vol.67 (1), p.450-466

2024

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Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1′-region optimisation

European journal of medicinal chemistry, 2023-02, Vol.248, p.115051, Article 115051

2023

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A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase

The Journal of biological chemistry, 2022-07, Vol.298 (7), p.102119, Article 102119

2022

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X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Biochemical journal, 2020-10, Vol.477 (19), p.3819-3832

2020

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Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

Nature communications, 2014-10, Vol.5 (1), p.5078-5078, Article 5078

2014

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Structural basis for substrate selection by the translocation and assembly module of the β‐barrel assembly machinery

Molecular microbiology, 2017-10, Vol.106 (1), p.142-156

2017

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Discovery of an archetypal protein transport system in bacterial outer membranes

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

Dynamic Association of BAM Complex Modules Includes Surface Exposure of the Lipoprotein BamC

The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons

Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability

Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity

Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp

A bioinformatic strategy for the detection, classification and analysis of bacterial autotransporters

Dissecting EXP2 sequence requirements for protein export in malaria parasites

Evolution of the β-barrel assembly machinery

Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria

Understanding the structure and function of Plasmodium aminopeptidases to facilitate drug discovery

Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein

Assembly of β-barrel proteins into bacterial outer membranes

Structural and functional requirements for activity of the Tim9-Tim10 complex in mitochondrial protein import

A Small Tim Homohexamer in the Relict Mitochondrion of Cryptosporidium

Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases

Design, Synthesis, and Evaluation of Cephamycin-Based Antisporulation Agents targeting Clostridioides difficile

Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1′-region optimisation

A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase

X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

Structural basis for substrate selection by the translocation and assembly module of the β‐barrel assembly machinery

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