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A discovery study of daunorubicin induced cardiotoxicity in a sample of acute myeloid leukemia patients prioritizes P450 oxidoreductase polymorphisms as a potential risk factor

Frontiers in genetics, 2013, Vol.4, p.231

2013

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Cytochrome P4502D6 ( ) Gene Locus Heterogeneity: Characterization of Gene Duplication Events

Clinical pharmacology and therapeutics, 2007-02, Vol.81 (2), p.242-251

2007

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A validated enantioselective assay for the simultaneous quantitation of ( R)-, ( S)-fluoxetine and ( R)-, ( S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS)

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-02, Vol.879 (5), p.349-358

2011

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Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin

Drug metabolism and disposition, 2009-05, Vol.37 (5), p.1107

2009

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Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism

The Journal of pharmacology and experimental therapeutics, 2010-03, Vol.332 (3), p.755

2010

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The effect of operational stressors on ibuprofen pharmacokinetics

European journal of clinical pharmacology, 2013, Vol.69 (1), p.31-41

2013

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Validation of a sequential extraction and liquid chromatography–tandem mass spectrometric method for determination of dihydrotestosterone, androstanediol and androstanediol–glucuronide in prostate tissues

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-08, Vol.902, p.84-95

2012

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Pharmacogenetic Impact of UDP-Glucuronosyltransferase Metabolic Pathway and Multidrug Resistance-Associated Protein 2 Transport Pathway on Mycophenolic Acid in Thoracic Transplant Recipients: An Exploratory Study

Pharmacotherapy, 2010-11, Vol.30 (11), p.1097-1108

2010

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The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone

The Journal of pharmacology and experimental therapeutics, 2009-06, Vol.329 (3), p.1032

2009

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Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin

Drug metabolism and disposition, 2008-05, Vol.36 (5), p.904

2008

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A correlation between cytotoxicity and reductase-mediated metabolism in cell lines treated with doxorubicin and daunorubicin

The Journal of pharmacology and experimental therapeutics, 2013-11, Vol.347 (2), p.375

2013

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Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin

The Journal of pharmacology and experimental therapeutics, 2010-12, Vol.335 (3), p.533

2010

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Validated assay for the simultaneous determination of cortisol and budesonide in human plasma using ultra high performance liquid chromatography–tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2014-03, Vol.90, p.198-206

2014

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An in vivo evaluation of the ontogeny of stereoselective fluoxetine metabolism and disposition in lambs from birth to one year of age

Xenobiotica, 2019-11, Vol.49 (11), p.1360-1372

2019

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Pharmacokinetics of mycophenolic acid and its phenolic-glucuronide and ACYl glucuronide metabolites in stable thoracic transplant recipients

Therapeutic drug monitoring, 2008-06, Vol.30 (3), p.282

2008

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Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro

Drug metabolism and disposition, 2008-06, Vol.36 (6), p.991

2008

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A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.955

2006

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Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1380

2007

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Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.212

2004

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The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1285

2007

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A validated assay to quantitate serotonin in lamb plasma using ultrahigh-performance liquid chromatography-tandem mass spectrometry: applications with LC/MS3

Analytical and bioanalytical chemistry, 2014-08, Vol.406 (20), p.5055-5059

2014

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Limited Sampling Strategy for Predicting Area Under the Concentration-Time Curve of Mycophenolic Acid in Adult Lung Transplant Recipients

Pharmacotherapy, 2006-09, Vol.26 (9), p.1232-1240

2006

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Enzyme-inducing Anticonvulsants Increase Plasma Clearance of Dexmedetomidine: A Pharmacokinetic and Pharmacodynamic Study

Anesthesiology (Philadelphia), 2014-05, Vol.120 (5), p.1118-1125

2014

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Single-Nucleotide Polymorphisms in Aldo-Keto and Carbonyl Reductase Genes Are Not Associated with Acute Cardiotoxicity after Daunorubicin Chemotherapy

Cancer epidemiology, biomarkers & prevention, 2012-11, Vol.21 (11), p.2118-2120

2012

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Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast‐feeding

British journal of clinical pharmacology, 2006-02, Vol.61 (2), p.155-163

2006

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A discovery study of daunorubicin induced cardiotoxicity in a sample of acute myeloid leukemia patients prioritizes P450 oxidoreductase polymorphisms as a potential risk factor

Cytochrome P4502D6 ( ) Gene Locus Heterogeneity: Characterization of Gene Duplication Events

A validated enantioselective assay for the simultaneous quantitation of ( R)-, ( S)-fluoxetine and ( R)-, ( S)-norfluoxetine in ovine plasma using liquid chromatography with tandem mass spectrometry (LC/MS/MS)

Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin

Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism

The effect of operational stressors on ibuprofen pharmacokinetics

Validation of a sequential extraction and liquid chromatography–tandem mass spectrometric method for determination of dihydrotestosterone, androstanediol and androstanediol–glucuronide in prostate tissues

Pharmacogenetic Impact of UDP-Glucuronosyltransferase Metabolic Pathway and Multidrug Resistance-Associated Protein 2 Transport Pathway on Mycophenolic Acid in Thoracic Transplant Recipients: An Exploratory Study

The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone

Two allelic variants of aldo-keto reductase 1A1 exhibit reduced in vitro metabolism of daunorubicin

A correlation between cytotoxicity and reductase-mediated metabolism in cell lines treated with doxorubicin and daunorubicin

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin

Validated assay for the simultaneous determination of cortisol and budesonide in human plasma using ultra high performance liquid chromatography–tandem mass spectrometry

An in vivo evaluation of the ontogeny of stereoselective fluoxetine metabolism and disposition in lambs from birth to one year of age

Pharmacokinetics of mycophenolic acid and its phenolic-glucuronide and ACYl glucuronide metabolites in stable thoracic transplant recipients

Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro

A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism

Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation

Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep

The use of microdialysis for the study of drug kinetics: central nervous system pharmacokinetics of diphenhydramine in fetal, newborn, and adult sheep

A validated assay to quantitate serotonin in lamb plasma using ultrahigh-performance liquid chromatography-tandem mass spectrometry: applications with LC/MS3

Limited Sampling Strategy for Predicting Area Under the Concentration-Time Curve of Mycophenolic Acid in Adult Lung Transplant Recipients

Enzyme-inducing Anticonvulsants Increase Plasma Clearance of Dexmedetomidine: A Pharmacokinetic and Pharmacodynamic Study

Single-Nucleotide Polymorphisms in Aldo-Keto and Carbonyl Reductase Genes Are Not Associated with Acute Cardiotoxicity after Daunorubicin Chemotherapy

Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast‐feeding

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