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Child Health, Developmental Plasticity, and Epigenetic Programming

Endocrine reviews, 2011-04, Vol.32 (2), p.159-224

2011

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Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone

The Journal of biological chemistry, 1992-02, Vol.267 (6), p.3915-3921

1992

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Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes

The Journal of biological chemistry, 1992-02, Vol.267 (6), p.3907-3914

1992

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Dual E1A oncolytic adenovirus: targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3 MUC1 and hTERT

Cancer gene therapy, 2011-03, Vol.18 (3), p.153-166

2011

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Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile

Oncogene, 2009-05, Vol.28 (20), p.2100-2111

2009

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Hepatic P-450 cholesterol 7 alpha-hydroxylase. Regulation in vivo at the protein and mRNA level in response to mevalonate, diurnal rhythm, and bile acid feedback

The Journal of biological chemistry, 1990-09, Vol.265 (25), p.15090-15095

1990

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Potentiation of methoxymorpholinyl doxorubicin antitumor activity by P450 3A4 gene transfer

Cancer gene therapy, 2009-05, Vol.16 (5), p.393-404

2009

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Evaluation of Triacetyloleandomycin, α-Nasymphthoflavone and Diethyldithiocarbamate as Selective Chemical Probes for Inhibition of Human Cytochromes P450

Archives of biochemistry and biophysics, 1994-06, Vol.311 (2), p.437-442

1994

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Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes

Archives of biochemistry and biophysics, 1995-07, Vol.320 (2), p.380-389

1995

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Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

The Journal of biological chemistry, 1996-03, Vol.271 (10), p.5929-5940

1996

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Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model

Cancer gene therapy, 2007-12, Vol.14 (12), p.935-944

2007

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Phenobarbital induction of cytochrome P-450 in normal and preneoplastic rat liver: comparison of enzyme and mRNA expression as detected by immunohistochemistry and in situ hybridization

Carcinogenesis (New York), 1987-09, Vol.8 (9), p.1355-1357

1987

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Pulsatility of growth hormone (GH) signalling in liver cells: Role of the JAK-STAT5b pathway in GH action

Growth hormone & IGF research, 2000-04, Vol.10, p.S1-S8

2000

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Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression

The Journal of biological chemistry, 1994-05, Vol.269 (20), p.14681-14689

1994

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[24] Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes

Methods in Enzymology, 1991, Vol.206, p.249-267

Waxman, David J.

1991

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Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms

The Journal of biological chemistry, 1992-02, Vol.267 (5), p.3294-3301

1992

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Sex-dependent expression and growth hormone regulation of class Alpha and class Mu glutathione S-transferase mRNAs in adult rat liver

Biochemical journal, 1993-08, Vol.294 (1), p.159-165

1993

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Growth Hormone-Dependent and -Independent Sexually Dimorphic Regulation of Phenobarbital-Induced Hepatic Cytochrome P450 2B1 and -2B2

Archives of biochemistry and biophysics, 1994-07, Vol.312 (1), p.234-239

1994

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Denitrosation of the Anti-Cancer Drug 1,3-Bis(2-chloroethyl)-1-nitrosourea Catalyzed by Microsomal Glutathione S-Transferase and Cytochrome P450 Monooxygenases

Archives of biochemistry and biophysics, 1993-12, Vol.307 (2), p.369-378

1993

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Pretranslational control by thyroid hormone of rat liver steroid 5 alpha-reductase and comparison to the thyroid dependence of two growth hormone-regulated CYP2C mRNAs

The Journal of biological chemistry, 1990-11, Vol.265 (31), p.19223-19229

1990

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Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7

The Journal of biological chemistry, 1994-05, Vol.269 (20)

1994

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Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo

Biochemistry (Easton), 1989-04, Vol.28 (8), p.3145-3152

1989

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Sequence of active site peptides from the penicillin-sensitive D-alanine carboxypeptidase of Bacillus subtilis. Mechanism of penicillin action and sequence homology to beta-lactamases

The Journal of biological chemistry, 1980-05, Vol.255 (9), p.3964-3976

1980

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Cleavage of a COOH-terminal hydrophobic region from D-alanine carboxypeptidase, a penicillin-sensitive bacterial membrane enzyme. Characterization of active, water-soluble fragments

The Journal of biological chemistry, 1979-06, Vol.254 (11), p.4863-4875

1979

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Primary structure of the COOH-terminal membranous segment of a penicillin-sensitive enzyme purified from two Bacilli

The Journal of biological chemistry, 1981-02, Vol.256 (4), p.2067-2077

1981

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Child Health, Developmental Plasticity, and Epigenetic Programming

Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone

Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes

Dual E1A oncolytic adenovirus: targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3 MUC1 and hTERT

Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile

Hepatic P-450 cholesterol 7 alpha-hydroxylase. Regulation in vivo at the protein and mRNA level in response to mevalonate, diurnal rhythm, and bile acid feedback

Potentiation of methoxymorpholinyl doxorubicin antitumor activity by P450 3A4 gene transfer

Evaluation of Triacetyloleandomycin, α-Nasymphthoflavone and Diethyldithiocarbamate as Selective Chemical Probes for Inhibition of Human Cytochromes P450

Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes

Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model

Phenobarbital induction of cytochrome P-450 in normal and preneoplastic rat liver: comparison of enzyme and mRNA expression as detected by immunohistochemistry and in situ hybridization

Pulsatility of growth hormone (GH) signalling in liver cells: Role of the JAK-STAT5b pathway in GH action

Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression

[24] Rat hepatic P450IIA and P450IIC subfamily expression using catalytic, immunochemical, and molecular probes

Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms

Sex-dependent expression and growth hormone regulation of class Alpha and class Mu glutathione S-transferase mRNAs in adult rat liver

Growth Hormone-Dependent and -Independent Sexually Dimorphic Regulation of Phenobarbital-Induced Hepatic Cytochrome P450 2B1 and -2B2

Denitrosation of the Anti-Cancer Drug 1,3-Bis(2-chloroethyl)-1-nitrosourea Catalyzed by Microsomal Glutathione S-Transferase and Cytochrome P450 Monooxygenases

Pretranslational control by thyroid hormone of rat liver steroid 5 alpha-reductase and comparison to the thyroid dependence of two growth hormone-regulated CYP2C mRNAs

Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7

Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo

Sequence of active site peptides from the penicillin-sensitive D-alanine carboxypeptidase of Bacillus subtilis. Mechanism of penicillin action and sequence homology to beta-lactamases

Cleavage of a COOH-terminal hydrophobic region from D-alanine carboxypeptidase, a penicillin-sensitive bacterial membrane enzyme. Characterization of active, water-soluble fragments

Primary structure of the COOH-terminal membranous segment of a penicillin-sensitive enzyme purified from two Bacilli

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