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International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases

Pharmacological reviews, 2017-04, Vol.69 (2), p.93-139

2017

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Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers

ACS nano, 2014-04, Vol.8 (4), p.3347-3356

2014

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Physiological roles of mammalian transmembrane adenylyl cyclase isoforms

Physiological reviews, 2022-04, Vol.102 (2), p.815-857

2022

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Selective Adenylyl Cyclase Type 1 Inhibitors as Potential Opioid Alternatives For Chronic Pain

Neuropsychopharmacology (New York, N.Y.), 2018-01, Vol.43 (1), p.215-216

Watts, Val J

2018

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Discovery of a Potent and Selective human AC2 inhibitor based on 7-Deazapurine Analogues of Adefovir

Bioorganic & medicinal chemistry, 2023-11, Vol.95, p.117508-117508, Article 117508

2023

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Biochemical pharmacology of adenylyl cyclases in cancer

Biochemical pharmacology, 2024-03, p.116160-116160, Article 116160

2024

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Insights into the Regulatory Properties of Human Adenylyl Cyclase Type 9

Molecular pharmacology, 2019-04, Vol.95 (4), p.349-360

2019

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Editorial: Adenylyl cyclase isoforms as potential drug targets

Frontiers in pharmacology, 2022-12, Vol.13, p.1098240-1098240

2022

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Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors

PLoS neglected tropical diseases, 2015-03, Vol.9 (3), p.e0003515

2015

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The CUL3/neddylation inhibitor MLN4924 reduces ethanol-induced locomotor sensitization and inflammatory pain allodynia in mice

Behavioural brain research, 2021-02, Vol.399, p.113051-113051, Article 113051

2021

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Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype

Frontiers in pharmacology, 2022-09, Vol.13, p.977742-977742

2022

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Palladium-Catalyzed Regio- and Stereoselective γ‑Arylation of Tertiary Allylic Amines: Identification of Potent Adenylyl Cyclase Inhibitors

Organic letters, 2015-02, Vol.17 (4), p.892-895

2015

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Genomics, GPCRs and new targets for the control of insect pests and vectors

Current opinion in insect science, 2018-12, Vol.30, p.99-106

2018

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A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling

Molecular pharmacology, 2018-09, Vol.94 (3), p.963-972

2018

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Optimization of a 1,3,4-oxadiazole series for inhibition of Ca2+/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain

European journal of medicinal chemistry, 2019-01, Vol.162, p.568-585

2019

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Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers

The Journal of pharmacology and experimental therapeutics, 2010-03, Vol.332 (3), p.710

2010

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A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors

PLoS neglected tropical diseases, 2012-01, Vol.6 (1), p.e1478

2012

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Reduced activity of adenylyl cyclase 1 attenuates morphine induced hyperalgesia and inflammatory pain in mice

Frontiers in pharmacology, 2022-09, Vol.13, p.937741-937741

2022

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Genome-Wide Small Interfering RNA Screening Reveals a Role for Cullin3-Really Interesting New Gene Ligase Signaling in Heterologous Sensitization of Adenylyl Cyclase

The Journal of pharmacology and experimental therapeutics, 2020-03, Vol.372 (3), p.267

2020

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Optimization of a Pyrimidinone Series for Selective Inhibition of Ca 2+ /Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.4667-4686

2022

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Optimization of a Pyrimidinone Series for Selective Inhibition of Ca2+/Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.4667-4686

2022

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New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling

Biochemical pharmacology, 2015-01, Vol.93 (1), p.85-91

2015

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Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Science signaling, 2017-02, Vol.10 (467)

2017

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Fluorescent and Bioluminescent Protein-Fragment Complementation Assays in the Study of G Protein-Coupled Receptor Oligomerization and Signaling

Molecular pharmacology, 2009-04, Vol.75 (4), p.733-739

2009

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Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases

European journal of medicinal chemistry, 2021-10, Vol.222, p.113581-113581, Article 113581

2021

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International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases

Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers

Physiological roles of mammalian transmembrane adenylyl cyclase isoforms

Selective Adenylyl Cyclase Type 1 Inhibitors as Potential Opioid Alternatives For Chronic Pain

Discovery of a Potent and Selective human AC2 inhibitor based on 7-Deazapurine Analogues of Adefovir

Biochemical pharmacology of adenylyl cyclases in cancer

Insights into the Regulatory Properties of Human Adenylyl Cyclase Type 9

Editorial: Adenylyl cyclase isoforms as potential drug targets

Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors

The CUL3/neddylation inhibitor MLN4924 reduces ethanol-induced locomotor sensitization and inflammatory pain allodynia in mice

Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype

Palladium-Catalyzed Regio- and Stereoselective γ‑Arylation of Tertiary Allylic Amines: Identification of Potent Adenylyl Cyclase Inhibitors

Genomics, GPCRs and new targets for the control of insect pests and vectors

A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling

Optimization of a 1,3,4-oxadiazole series for inhibition of Ca2+/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain

Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers

A “Genome-to-Lead” Approach for Insecticide Discovery: Pharmacological Characterization and Screening of Aedes aegypti D1-like Dopamine Receptors

Reduced activity of adenylyl cyclase 1 attenuates morphine induced hyperalgesia and inflammatory pain in mice

Genome-Wide Small Interfering RNA Screening Reveals a Role for Cullin3-Really Interesting New Gene Ligase Signaling in Heterologous Sensitization of Adenylyl Cyclase

Optimization of a Pyrimidinone Series for Selective Inhibition of Ca 2+ /Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain

Optimization of a Pyrimidinone Series for Selective Inhibition of Ca2+/Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain

New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Fluorescent and Bioluminescent Protein-Fragment Complementation Assays in the Study of G Protein-Coupled Receptor Oligomerization and Signaling

Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases

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