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Transmission of multiple system atrophy prions to transgenic mice

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19555-19560

2013

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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (38), p.E5308-E5317

2015

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Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10323-10328

2014

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The function of the cellular prion protein in health and disease

Acta neuropathologica, 2018-02, Vol.135 (2), p.159-178

2018

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Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.11025-11030

2012

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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10329-10334

2014

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Propagation of prions causing synucleinopathies in cultured cells

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (35), p.E4949-E4958

2015

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Evolutionary descent of prion genes from the ZIP family of metal ion transporters

PloS one, 2009-09, Vol.4 (9), p.e7208-e7208

2009

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The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

PloS one, 2021-11, Vol.16 (11), p.e0258682-e0258682

2021

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Drug resistance confounding prion therapeutics

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.E4160-E4169

2013

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Cellular models for discovering prion disease therapeutics: Progress and challenges

Journal of neurochemistry, 2020-04, Vol.153 (2), p.150-172

2020

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Full restoration of specific infectivity and strain properties from pure mammalian prion protein

PLoS pathogens, 2019-03, Vol.15 (3), p.e1007662

2019

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Evidence that bank vole PrP is a universal acceptor for prions

PLoS pathogens, 2014-04, Vol.10 (4), p.e1003990-e1003990

2014

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Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease

PLoS pathogens, 2024-04, Vol.20 (4), p.e1012087-e1012087

2024

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“Prion-like” seeding and propagation of oligomeric protein assemblies in neurodegenerative disorders

Frontiers in neuroscience, 2024-08, Vol.18, p.1436262

2024

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Upregulated pexophagy limits the capacity of selective autophagy

Nature communications, 2024-01, Vol.15 (1), p.375-375, Article 375

2024

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The prion protein family: Diversity, rivalry, and dysfunction

Biochimica et biophysica acta, 2007-06, Vol.1772 (6), p.654-672

2007

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Towards authentic transgenic mouse models of heritable PrP prion diseases

Acta neuropathologica, 2016-10, Vol.132 (4), p.593-610

2016

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Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008875-e1008875

2020

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Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (6), p.2528-2533

2011

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The expanding universe of prion diseases

PLoS pathogens, 2006-03, Vol.2 (3), p.e26-e26

2006

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Calling α-synuclein a prion is scientifically justifiable

Acta neuropathologica, 2019-10, Vol.138 (4), p.505-508

Watts, Joel C.

2019

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Structural Studies of Truncated Forms of the Prion Protein PrP

Biophysical journal, 2015-03, Vol.108 (6), p.1548-1554

2015

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Protease-resistant prions selectively decrease Shadoo protein

PLoS pathogens, 2011-11, Vol.7 (11), p.e1002382-e1002382

2011

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Sensitive protein misfolding cyclic amplification of sporadic Creutzfeldt-Jakob disease prions is strongly seed and substrate dependent

Scientific reports, 2021-02, Vol.11 (1), p.4058-12, Article 4058

2021

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Transmission of multiple system atrophy prions to transgenic mice

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

The function of the cellular prion protein in health and disease

Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

Propagation of prions causing synucleinopathies in cultured cells

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

The cellular prion protein interacts with and promotes the activity of Na,K-ATPases

Drug resistance confounding prion therapeutics

Cellular models for discovering prion disease therapeutics: Progress and challenges

Full restoration of specific infectivity and strain properties from pure mammalian prion protein

Evidence that bank vole PrP is a universal acceptor for prions

Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease

“Prion-like” seeding and propagation of oligomeric protein assemblies in neurodegenerative disorders

Upregulated pexophagy limits the capacity of selective autophagy

The prion protein family: Diversity, rivalry, and dysfunction

Towards authentic transgenic mouse models of heritable PrP prion diseases

Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease

The expanding universe of prion diseases

Calling α-synuclein a prion is scientifically justifiable

Structural Studies of Truncated Forms of the Prion Protein PrP

Protease-resistant prions selectively decrease Shadoo protein

Sensitive protein misfolding cyclic amplification of sporadic Creutzfeldt-Jakob disease prions is strongly seed and substrate dependent

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