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An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3465-3470

2003

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Myosin light chain kinase (210 kDa) is a potential cytoskeleton integrator through its unique N-terminal domain

Experimental cell research, 2004-08, Vol.298 (2), p.407-417

2004

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Screening in a cell-based assay for inhibitors of microglial nitric oxide production reveals calmodulin-regulated protein kinases as potential drug discovery targets

Brain research, 1999-10, Vol.844 (1), p.126-134

1999

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Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo

Neurobiology of aging, 2004-11, Vol.25 (10), p.1283-1292

2004

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DAPK catalytic activity in the hippocampus increases during the recovery phase in an animal model of brain hypoxic-ischemic injury

Biochimica et biophysica acta, 2002-11, Vol.1600 (1), p.128-137

2002

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Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II

Neurochemistry international, 2001-11, Vol.39 (5), p.459-468

2001

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Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands

Neurobiology of aging, 2001-11, Vol.22 (6), p.975-981

2001

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Structure, activity, regulation, and inhibitor discovery for a protein kinase associated with apoptosis and neuronal death

Pharmacology & therapeutics (Oxford), 2002-02, Vol.93 (2), p.217-224

2002

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Affinity chromatography purification of a cyclic nucleotide phosphodiesterase using immobilized modulator protein, a troponin C-like protein from brain

Biochemical and biophysical research communications, 1976-11, Vol.73 (1), p.40-46

1976

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Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton

FEBS letters, 1999-12, Vol.463 (1), p.67-71

1999

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Identification of calcium binding sites in the trypanosome flagellar calcium-acyl switch protein

Molecular and biochemical parasitology, 1999-06, Vol.101 (1), p.61-70

1999

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Mutation of Lys-75 affects calmodulin conformation

FEBS letters, 1999-04, Vol.450 (1), p.139-143

1999

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Interaction of smooth muscle caldesmon with calmodulin mutants

FEBS letters, 1995-02, Vol.360 (1), p.89-92

1995

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Analysis of differences between Coomassie blue stain and silver stain procedures in polyacrylamide gels: Conditions for the detection of calmodulin and troponin C

Analytical biochemistry, 1983-06, Vol.131 (2), p.312-317

1983

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Gain of function mutations for yeast calmodulin and calcium dependent regulation of protein kinase activity

Biochimica et biophysica acta, 1994-09, Vol.1223 (3), p.341-347

1994

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Replacement of Lys-75 of calmodulin affects its interaction with smooth muscle caldesmon

Biochimica et biophysica acta, 2001-01, Vol.1544 (1), p.143-150

2001

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[26] Purification of calmodulin and preparation of immobilized calmodulin

Methods in Enzymology, 1988, Vol.157, p.328-339

1988

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Metabolically 35S-labeled recombinant calmodulin as a ligand for the detection of calmodulin-binding proteins

Analytical biochemistry, 1989-04, Vol.178 (1), p.141-147

1989

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[24] The use of synthetic oligodeoxyribonucleotides in the examination of calmodulin gene and protein structure and function

Methods in Enzymology, 1987, Vol.139, p.290-303

1987

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Isolation and characterization of calmodulin from the motile green alga Chlamydomonas reinhardtii

Archives of biochemistry and biophysics, 1984-02, Vol.229 (1), p.33-42

1984

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Structural characterization of the calcium binding protein S100 from adipose tissue

Archives of biochemistry and biophysics, 1985-08, Vol.240 (2), p.777-780

1985

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The heterodimer calmodulin: myosin light-chain kinase as a prototype vertebrate calcium signal transduction complex

Biochimica et biophysica acta, 1992-11, Vol.1160 (1), p.8-15

1992

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Elucidation of a minimal immunoreactive site of vertebrate calmodulin

Archives of biochemistry and biophysics, 1983-12, Vol.227 (2), p.522-533

1983

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Amino acid sequence of the phosphorylation site of bovine cardiac myosin light chain

Archives of biochemistry and biophysics, 1985-05, Vol.238 (2), p.664-669

1985

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Rapid separation and quantitation of 3′,5′-cyclic nucleotides and 5′-nucleotides in phosphodiesterase reaction mixtures using high-performance liquid chromatography

Journal of biochemical and biophysical methods, 1980-03, Vol.2 (3), p.139-146

1980

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An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury

Myosin light chain kinase (210 kDa) is a potential cytoskeleton integrator through its unique N-terminal domain

Screening in a cell-based assay for inhibitors of microglial nitric oxide production reveals calmodulin-regulated protein kinases as potential drug discovery targets

Aminopyridazines inhibit β-amyloid-induced glial activation and neuronal damage in vivo

DAPK catalytic activity in the hippocampus increases during the recovery phase in an animal model of brain hypoxic-ischemic injury

Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II

Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands

Structure, activity, regulation, and inhibitor discovery for a protein kinase associated with apoptosis and neuronal death

Affinity chromatography purification of a cyclic nucleotide phosphodiesterase using immobilized modulator protein, a troponin C-like protein from brain

Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton

Identification of calcium binding sites in the trypanosome flagellar calcium-acyl switch protein

Mutation of Lys-75 affects calmodulin conformation

Interaction of smooth muscle caldesmon with calmodulin mutants

Analysis of differences between Coomassie blue stain and silver stain procedures in polyacrylamide gels: Conditions for the detection of calmodulin and troponin C

Gain of function mutations for yeast calmodulin and calcium dependent regulation of protein kinase activity

Replacement of Lys-75 of calmodulin affects its interaction with smooth muscle caldesmon

[26] Purification of calmodulin and preparation of immobilized calmodulin

Metabolically 35S-labeled recombinant calmodulin as a ligand for the detection of calmodulin-binding proteins

[24] The use of synthetic oligodeoxyribonucleotides in the examination of calmodulin gene and protein structure and function

Isolation and characterization of calmodulin from the motile green alga Chlamydomonas reinhardtii

Structural characterization of the calcium binding protein S100 from adipose tissue

The heterodimer calmodulin: myosin light-chain kinase as a prototype vertebrate calcium signal transduction complex

Elucidation of a minimal immunoreactive site of vertebrate calmodulin

Amino acid sequence of the phosphorylation site of bovine cardiac myosin light chain

Rapid separation and quantitation of 3′,5′-cyclic nucleotides and 5′-nucleotides in phosphodiesterase reaction mixtures using high-performance liquid chromatography

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