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Mitoxantrone, More than Just Another Topoisomerase II Poison

Medicinal research reviews, 2016-03, Vol.36 (2), p.248-299

2016

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different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20723-20727

2009

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Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity

Antimicrobial Agents and Chemotherapy, 2009-07, Vol.53 (7), p.2824-2833

2009

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Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library

Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1712-1719

2010

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Structure-guided design of a selective BCL-XL inhibitor

Nature chemical biology, 2013-06, Vol.9 (6), p.390-397

2013

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Role of Fusobacterium nucleatum and Coaggregation in Anaerobe Survival in Planktonic and Biofilm Oral Microbial Communities during Aeration

Infection and Immunity, 1998-10, Vol.66 (10), p.4729-4732

1998

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2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (8), p.2051-2055

2005

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Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agents

Bioorganic & medicinal chemistry letters, 2021-03, Vol.35, p.127813-127813, Article 127813

2021

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A Concise Total Synthesis of Naamidine A

Organic letters, 2006-02, Vol.8 (3), p.419-421

2006

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Structure-Guided Rescaffolding of Selective Antagonists of BCL‑XL

ACS medicinal chemistry letters, 2014-06, Vol.5 (6), p.662-667

2014

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New Anthracenedione Derivatives with Improved Biological Activity by Virtue of Stable Drug−DNA Adduct Formation

Journal of medicinal chemistry, 2010-10, Vol.53 (19), p.6851-6866

2010

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Synthesis and biological evaluation of analogues of the anti-tumor alkaloid naamidine A

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3741-3744

2007

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An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus

ACS medicinal chemistry letters, 2012-04, Vol.3 (4), p.303-307

2012

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Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Journal of medicinal chemistry, 2005-04, Vol.48 (8), p.2964-2971

2005

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Depth Penetration and Detection of pH Gradients in Biofilms by Two-Photon Excitation Microscopy

Applied and Environmental Microbiology, 1999-08, Vol.65 (8), p.3502-3511

1999

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M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

Biochemical pharmacology, 2011-12, Vol.82 (11), p.1604-1618

2011

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Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1422-1427

2007

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Dimeric cyclohexane-1,3-dione oximes inhibit wheat acetyl-CoA carboxylase and show anti-malarial activity

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4611-4613

2010

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Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4542-4549

2004

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Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1589-1592

2004

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Cyclohexane-1,3-dione Oxime Ether Grass-Specific Herbicides and the Discovery of Butroxydim

Australian journal of chemistry, 2011, Vol.64 (4), p.367

Watson, Keith G.

2011

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Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG1478-mesylate, with albumin

Analytical biochemistry, 2005-07, Vol.342 (2), p.292-299

2005

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Mitoxantrone, More than Just Another Topoisomerase II Poison

different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim

Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity

Inhibitors of Leishmania GDP-Mannose Pyrophosphorylase Identified by High-Throughput Screening of Small-Molecule Chemical Library

Structure-guided design of a selective BCL-XL inhibitor

Role of Fusobacterium nucleatum and Coaggregation in Anaerobe Survival in Planktonic and Biofilm Oral Microbial Communities during Aeration

Discovery of a Potent and Selective BCL‑XL Inhibitor with in Vivo Activity

2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder

Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agents

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

A Concise Total Synthesis of Naamidine A

Structure-Guided Rescaffolding of Selective Antagonists of BCL‑XL

New Anthracenedione Derivatives with Improved Biological Activity by Virtue of Stable Drug−DNA Adduct Formation

Synthesis and biological evaluation of analogues of the anti-tumor alkaloid naamidine A

An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus

Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Depth Penetration and Detection of pH Gradients in Biofilms by Two-Photon Excitation Microscopy

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

Dimeric cyclohexane-1,3-dione oximes inhibit wheat acetyl-CoA carboxylase and show anti-malarial activity

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

Cyclohexane-1,3-dione Oxime Ether Grass-Specific Herbicides and the Discovery of Butroxydim

Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG1478-mesylate, with albumin

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