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Antimalarial dosing regimens and drug resistance

Trends in parasitology, 2008-03, Vol.24 (3), p.127-134

2008

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WHO, the Global Fund, and medical malpractice in malaria treatment

The Lancet (British edition), 2004-01, Vol.363 (9404), p.237-240

2004

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Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?

Trends in Parasitology, 2001-12, Vol.17 (12), p.582-588

2001

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The evolution of drug-resistant malaria: the role of drug elimination half-life

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2002-04, Vol.357 (1420), p.505-519

2002

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Averting a malaria disaster

The Lancet (British edition), 1999-06, Vol.353 (9168), p.1965-1967

1999

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Tolerance is the key to understanding antimalarial drug resistance

Trends in parasitology, 2006-02, Vol.22 (2), p.71-77

2006

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Intensity of malaria transmission and the evolution of drug resistance

Acta tropica, 2005-06, Vol.94 (3), p.218-229

2005

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A network to monitor antimalarial drug resistance: a plan for moving forward

Trends in parasitology, 2008-01, Vol.24 (1), p.43-48

2008

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Characteristics of Plasmodium falciparum dhfr Haplotypes That Confer Pyrimethamine Resistance, Kilifi, Kenya, 1987–2006

The Journal of infectious diseases, 2008-06, Vol.197 (12), p.1743-1751

2008

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Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites

Antimicrobial Agents and Chemotherapy, 2000-04, Vol.44 (4), p.991-996

2000

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Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropteroate Synthase and Epidemiologic Patterns of Pyrimethamine-Sulfadoxine Use and Resistance

The Journal of infectious diseases, 1997-12, Vol.176 (6), p.1590-1596

1997

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The ABO blood group system: historical background

Transfusion medicine (Oxford, England), 2001-08, Vol.11 (4), p.243-265

Watkins, W. M.

2001

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Changing home treatment of childhood fevers by training shop keepers in rural Kenya

Tropical medicine & international health, 1999-05, Vol.4 (5), p.383-389

1999

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Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long-Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter-Acting Chlorproguanil/Dapsone on Kenyan Plasmodium falciparum

The Journal of infectious diseases, 2000-06, Vol.181 (6), p.2023-2028

2000

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The efficacy of antimalarial monotherapies, sulphadoxine–pyrimethamine and amodiaquine in East Africa: implications for sub‐regional policy

Tropical medicine & international health, 2003-10, Vol.8 (10), p.860-867

2003

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Reduction of the efficacy of antifolate antimalarial therapy by folic acid supplementation

The American journal of tropical medicine and hygiene, 2005-07, Vol.73 (1), p.166-170

2005

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Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial

The Lancet (British edition), 2002-10, Vol.360 (9340), p.1136-1143

2002

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The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: a model of the selection of resistance by antifolate drugs and their combinations

The American journal of tropical medicine and hygiene, 2005-02, Vol.72 (2), p.163-173

2005

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Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

Molecular and biochemical parasitology, 1997-11, Vol.89 (2), p.161-177

1997

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Antimalarial benzo[ c]phenanthridines

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (8), p.2007-2010

2005

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Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1993, Vol.87 (1), p.75-78

1993

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Unravelling the biochemical basis of blood group ABO and Lewis antigenic specificity

Glycoconjugate journal, 2000-07, Vol.17 (7-9), p.501-530

2000

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Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain

Antimicrobial Agents and Chemotherapy, 1998-01, Vol.42 (1), p.164-169

1998

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Rare, Highly Pyrimethamine-Resistant Alleles of the Plasmodium falciparum Dihydrofolate Reductase Gene from 5 African Sites

The Journal of infectious diseases, 2004-11, Vol.190 (10), p.1783-1792

2004

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Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria

Antimicrobial Agents and Chemotherapy, 1997-10, Vol.41 (10), p.2261-2264

1997

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Antimalarial dosing regimens and drug resistance

WHO, the Global Fund, and medical malpractice in malaria treatment

Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?

The evolution of drug-resistant malaria: the role of drug elimination half-life

Averting a malaria disaster

Tolerance is the key to understanding antimalarial drug resistance

Intensity of malaria transmission and the evolution of drug resistance

A network to monitor antimalarial drug resistance: a plan for moving forward

Characteristics of Plasmodium falciparum dhfr Haplotypes That Confer Pyrimethamine Resistance, Kilifi, Kenya, 1987–2006

Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites

Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropteroate Synthase and Epidemiologic Patterns of Pyrimethamine-Sulfadoxine Use and Resistance

The ABO blood group system: historical background

Changing home treatment of childhood fevers by training shop keepers in rural Kenya

Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long-Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter-Acting Chlorproguanil/Dapsone on Kenyan Plasmodium falciparum

The efficacy of antimalarial monotherapies, sulphadoxine–pyrimethamine and amodiaquine in East Africa: implications for sub‐regional policy

Reduction of the efficacy of antifolate antimalarial therapy by folic acid supplementation

Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial

The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: a model of the selection of resistance by antifolate drugs and their combinations

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

Antimalarial benzo[ c]phenanthridines

Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life

Unravelling the biochemical basis of blood group ABO and Lewis antigenic specificity

Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain

Rare, Highly Pyrimethamine-Resistant Alleles of the Plasmodium falciparum Dihydrofolate Reductase Gene from 5 African Sites

Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria

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