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An Engineered Monovalent Anti–TNF-α Antibody with pH-Sensitive Binding Abrogates Immunogenicity in Mice following a Single Intravenous Dose

The Journal of immunology (1950), 2022-08, Vol.209 (4), p.829-839

2022

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Ultra-potent Antibodies Against Respiratory Syncytial Virus: Effects of Binding Kinetics and Binding Valence on Viral Neutralization

Journal of molecular biology, 2005-07, Vol.350 (1), p.126-144

2005

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Gene Transfer of Cocaine Hydrolase Suppresses Cardiovascular Responses to Cocaine in Rats

Molecular pharmacology, 2005-01, Vol.67 (1), p.204-211

2005

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Stepwise in vitro Affinity Maturation of Vitaxin, an αvβ3-specific Humanized mAb

Proceedings of the National Academy of Sciences - PNAS, 1998-05, Vol.95 (11), p.6037-6042

1998

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Optimization of protein therapeutics by directed evolution

Drug Discovery Today, 2003-02, Vol.8 (3), p.118-126

2003

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Screening of phage-expressed antibody libraries by capture lift

Methods in molecular biology (Clifton, N.J.), 2002, Vol.178, p.187

Watkins, Jeffry D

2002

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Expanding the clinical utility of therapeutic proteins: activated protein C variants with improved pharmacological properties

Trends in pharmacological sciences (Regular ed.), 2003-10, Vol.24 (10), p.501-504

2003

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Cloning, isolation and characterization of human tumor in situ monoclonal antibodies

Cancer Immunology, Immunotherapy, 2002-04, Vol.51 (2), p.79-90

2002

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Use of a Peptide Mimotope to Guide the Humanization of MRK-16, an Anti-P-glycoprotein Monoclonal Antibody

The Journal of biological chemistry, 1999-09, Vol.274 (39), p.27371-27378

1999

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Novel Protein Agonist of Thrombopoiesis Acts Via a Physiocrine Pathway Distinct From That of Thrombopoietin

Blood, 2011-11, Vol.118 (21), p.2376-2376

2011

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Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues

Journal of molecular biology, 1999-11, Vol.294 (1), p.151

1999

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Immunolocalization of membrane-associated CTP:phosphocholine cytidylyltransferase in phosphatidylcholine-deficient Chinese hamster ovary cells

The Journal of biological chemistry, 1992-03, Vol.267 (8), p.5686-5692

1992

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Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues 1 1Edited by J. A. Wells

Journal of molecular biology, 1999-11, Vol.294 (1), p.151-162

1999

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Phosphorylation of CTP:phosphocholine cytidylyltransferase in vivo. Lack of effect of phorbol ester treatment in HeLa cells

The Journal of biological chemistry, 1990-02, Vol.265 (4), p.2190-2197

1990

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In vitro affinity maturation of human IgM antibodies reactive with tumor-associated antigens

Hybridoma and hybridomics, 2001-01, Vol.20 (5-6), p.383-396

2001

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Discovery of Human Antibodies to Cell Surface Antigens by Capture Lift Screening of Phage-Expressed Antibody Libraries

Analytical biochemistry, 1998-02, Vol.256 (2), p.169-177

1998

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Targeted Antiangiogenic Therapy for Cancer Using Vitaxin: A Humanized Monoclonal Antibody to the Integrin ανβ3

Clinical cancer research, 2000-08, Vol.6 (8), p.3056

2000

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Determination of the Relative Affinities of Antibody Fragments Expressed inEscherichia coliby Enzyme-Linked Immunosorbent Assay

Analytical biochemistry, 1997-11, Vol.253 (1), p.37-45

1997

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Stepwise in vitro affinity maturation of Vitaxin, an α v β 3 -specific humanized mAb

Proceedings of the National Academy of Sciences - PNAS, 1998-05, Vol.95 (11), p.6037-6042

1998

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Determination of the relative affinities of antibody fragments expressed in Escherichia coli by enzyme-linked immunosorbent assay

Analytical biochemistry, 1997-11, Vol.253 (1), p.37

1997

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Regulation of CTP:phosphocholine cytidylyltransferase activity and phosphorylation in rat hepatocytes: Lack of effect of elevated cAMP levels

Archives of biochemistry and biophysics, 1992-02, Vol.292 (2), p.360-367

1992

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Oligomerization of immunoglobulin G heavy and light chains in vitro. A cell-free assay to study the assembly of the endoplasmic reticulum

The Journal of biological chemistry, 1993-03, Vol.268 (7), p.5182-5192

1993

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The effect of NaCl intake on 9-ketoprostaglandin reductase activity in the rabbit kidney

Prostaglandins, 1985-08, Vol.30 (2), p.335-349

1985

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Analysis of the effect of systemic corticosteroids on survival from tebentafusp in a phase 3 trial of metastatic uveal melanoma

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9584-9584

2022

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Radical-cation-initiated Diels-Alder di- and trimerization of 3,4-dimethoxypropenylbenzene: stereochemical correlation with the lignans galbulin and isogalbulin

Journal of the American Chemical Society, 1989-03, Vol.111 (5), p.1749-1754

1989

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An Engineered Monovalent Anti–TNF-α Antibody with pH-Sensitive Binding Abrogates Immunogenicity in Mice following a Single Intravenous Dose

Ultra-potent Antibodies Against Respiratory Syncytial Virus: Effects of Binding Kinetics and Binding Valence on Viral Neutralization

Gene Transfer of Cocaine Hydrolase Suppresses Cardiovascular Responses to Cocaine in Rats

Stepwise in vitro Affinity Maturation of Vitaxin, an αvβ3-specific Humanized mAb

Optimization of protein therapeutics by directed evolution

Screening of phage-expressed antibody libraries by capture lift

Expanding the clinical utility of therapeutic proteins: activated protein C variants with improved pharmacological properties

Cloning, isolation and characterization of human tumor in situ monoclonal antibodies

Use of a Peptide Mimotope to Guide the Humanization of MRK-16, an Anti-P-glycoprotein Monoclonal Antibody

Novel Protein Agonist of Thrombopoiesis Acts Via a Physiocrine Pathway Distinct From That of Thrombopoietin

Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues

Immunolocalization of membrane-associated CTP:phosphocholine cytidylyltransferase in phosphatidylcholine-deficient Chinese hamster ovary cells

Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues 1 1Edited by J. A. Wells

Phosphorylation of CTP:phosphocholine cytidylyltransferase in vivo. Lack of effect of phorbol ester treatment in HeLa cells

In vitro affinity maturation of human IgM antibodies reactive with tumor-associated antigens

Discovery of Human Antibodies to Cell Surface Antigens by Capture Lift Screening of Phage-Expressed Antibody Libraries

Targeted Antiangiogenic Therapy for Cancer Using Vitaxin: A Humanized Monoclonal Antibody to the Integrin ανβ3

Determination of the Relative Affinities of Antibody Fragments Expressed inEscherichia coliby Enzyme-Linked Immunosorbent Assay

Stepwise in vitro affinity maturation of Vitaxin, an α v β 3 -specific humanized mAb

Determination of the relative affinities of antibody fragments expressed in Escherichia coli by enzyme-linked immunosorbent assay

Regulation of CTP:phosphocholine cytidylyltransferase activity and phosphorylation in rat hepatocytes: Lack of effect of elevated cAMP levels

Oligomerization of immunoglobulin G heavy and light chains in vitro. A cell-free assay to study the assembly of the endoplasmic reticulum

The effect of NaCl intake on 9-ketoprostaglandin reductase activity in the rabbit kidney

Analysis of the effect of systemic corticosteroids on survival from tebentafusp in a phase 3 trial of metastatic uveal melanoma

Radical-cation-initiated Diels-Alder di- and trimerization of 3,4-dimethoxypropenylbenzene: stereochemical correlation with the lignans galbulin and isogalbulin

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