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Unveiling the intra-tumor fate of trastuzumab deruxtecan in a xenograft model to support its mechanism of action

Drug metabolism and pharmacokinetics, 2024-06, Vol.56, p.101001, Article 101001

2024

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Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers

Pharmaceutical research, 2018-07, Vol.35 (7), p.138-13, Article 138

2018

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Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models

Drug metabolism and disposition, 2020-04, Vol.48 (4), p.288-296

2020

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Relationships between time in range, glycemic variability including hypoglycemia and types of diabetes therapy in Japanese patients with type 2 diabetes mellitus: Hyogo Diabetes Hypoglycemia Cognition Complications study

Journal of diabetes investigation, 2021-02, Vol.12 (2), p.244-253

2021

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Circadian modulation in the intestinal absorption of P-glycoprotein substrates in monkeys

Molecular pharmacology, 2015-07, Vol.88 (1), p.29-37

2015

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Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies

Drug metabolism and pharmacokinetics, 2022-08, Vol.45, p.100459-100459, Article 100459

2022

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Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters

Drug metabolism and disposition, 2019-11, Vol.47 (11), p.1270

2019

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In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions

Xenobiotica, 2019-08, Vol.49 (8), p.961-969

2019

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Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents: a cross-sectional study in urban districts in Japan

Endocrine Journal, 2018, Vol.65(10), pp.1001-1009

2018

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Evaluation of the Usefulness of Breast Cancer Resistance Protein (BCRP) Knockout Mice and BCRP Inhibitor-Treated Monkeys to Estimate the Clinical Impact of BCRP Modulation on the Pharmacokinetics of BCRP Substrates

Pharmaceutical research, 2015-05, Vol.32 (5), p.1634-1647

2015

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Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (13), p.2949-2953

2014

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The Blood Glucose Level Increased in Parallel with the Heart Rate Following Cilostazol Administration in Three Diabetic Patients

Internal Medicine, 2014, Vol.53(8), pp.859-863

2014

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Control of Crystallographic Orientation and Structural Characteristics for Electrodeposited Aluminum

Electrochemistry, 2016/12/05, Vol.84(12), pp.953-958

2016

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Renadirsen, a Novel 2′OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo

Current issues in molecular biology, 2021-09, Vol.43 (3), p.1267-1281

2021

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Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (17), p.5546-5565

2015

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Association of urinary albumin excretion with periodontal parameters in patients with type 2 diabetes mellitus: a cross-sectional study

Diabetology international, 2020-04, Vol.11 (2), p.121-128

2020

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Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist

ACS medicinal chemistry letters, 2015-03, Vol.6 (3), p.266-270

2015

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Zn-Al2O3 Composites with High Aluminum Content and Nanostructured Al2O3/ZnO Prepared by Electrochemical Technique from Non-Suspended Solution

Electrochemistry, 2017/06/05, Vol.85(6), pp.315-318

2017

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Association between brain imaging biomarkers and continuous glucose monitoring-derived glycemic control indices in Japanese patients with type 2 diabetes mellitus

BMJ open diabetes research & care, 2024-01, Vol.12 (1), p.e003744

2024

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Structure–Activity Relationship Studies of 3- or 4‑Pyridine Derivatives of DS-6930

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.358-362

2019

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2'-O-Methyl RNA/Ethylene-Bridged Nucleic Acid Chimera Antisense Oligonucleotides to Induce Dystrophin Exon 45 Skipping

Genes, 2017-02, Vol.8 (2), p.67

2017

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Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents : a cross-sectional study in urban districts in Japan

ENDOCRINE JOURNAL, 2018, Vol.65 (10), p.1001-1009

2018

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Purification and Identification of Activating Enzymes of CS-0777, a Selective Sphingosine 1-Phosphate Receptor 1 Modulator, in Erythrocytes

The Journal of biological chemistry, 2011-07, Vol.286 (28), p.24765-24775

2011

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Infrared Absorption Films Developed by Copper Electroplating with Chemical Etching and Subsequent Blackening

Electrochemistry, 2014/09/05, Vol.82(9), pp.752-754

2014

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Cyanide Detection from Nickel Electrodeposited in Modified Watts Baths Including Glycine and Cyanide Production at Anodic Sides in the Baths

Electrochemistry, 2016/06/05, Vol.84(6), pp.394-397

2016

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Unveiling the intra-tumor fate of trastuzumab deruxtecan in a xenograft model to support its mechanism of action

Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers

Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models

Relationships between time in range, glycemic variability including hypoglycemia and types of diabetes therapy in Japanese patients with type 2 diabetes mellitus: Hyogo Diabetes Hypoglycemia Cognition Complications study

Circadian modulation in the intestinal absorption of P-glycoprotein substrates in monkeys

Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies

Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters

In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions

Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents: a cross-sectional study in urban districts in Japan

Evaluation of the Usefulness of Breast Cancer Resistance Protein (BCRP) Knockout Mice and BCRP Inhibitor-Treated Monkeys to Estimate the Clinical Impact of BCRP Modulation on the Pharmacokinetics of BCRP Substrates

Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists

The Blood Glucose Level Increased in Parallel with the Heart Rate Following Cilostazol Administration in Three Diabetic Patients

Control of Crystallographic Orientation and Structural Characteristics for Electrodeposited Aluminum

Renadirsen, a Novel 2′OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo

Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558

Association of urinary albumin excretion with periodontal parameters in patients with type 2 diabetes mellitus: a cross-sectional study

Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist

Zn-Al2O3 Composites with High Aluminum Content and Nanostructured Al2O3/ZnO Prepared by Electrochemical Technique from Non-Suspended Solution

Association between brain imaging biomarkers and continuous glucose monitoring-derived glycemic control indices in Japanese patients with type 2 diabetes mellitus

Structure–Activity Relationship Studies of 3- or 4‑Pyridine Derivatives of DS-6930

2'-O-Methyl RNA/Ethylene-Bridged Nucleic Acid Chimera Antisense Oligonucleotides to Induce Dystrophin Exon 45 Skipping

Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents : a cross-sectional study in urban districts in Japan

Purification and Identification of Activating Enzymes of CS-0777, a Selective Sphingosine 1-Phosphate Receptor 1 Modulator, in Erythrocytes

Infrared Absorption Films Developed by Copper Electroplating with Chemical Etching and Subsequent Blackening

Cyanide Detection from Nickel Electrodeposited in Modified Watts Baths Including Glycine and Cyanide Production at Anodic Sides in the Baths

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