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AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Nature communications, 2021-06, Vol.12 (1), p.3908-3908, Article 3908

2021

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Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Nature communications, 2021-07, Vol.12 (1), p.4500-4500, Article 4500

2021

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Targeted nonviral delivery of genome editors in vivo

Proceedings of the National Academy of Sciences - PNAS, 2024-03, Vol.121 (11), p.e2307796121-e2307796121

2024

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Deletion of CISH and TGFβR2 in iPSC-Derived NK Cells Promotes High Cytotoxicity and Enhances In Vivo Tumor Killing

Blood, 2021-11, Vol.138 (Supplement 1), p.2780-2780

2021

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A Bicistronic Vector Expressing CD16 and a Membrane Bound IL-15 Construct in iPSC Derived NK Cells Increased Cytotoxicity and Persistence

Blood, 2021-11, Vol.138 (Supplement 1), p.4809-4809

2021

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CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes

Nucleic acids research, 2024-01, Vol.52 (D1), p.D590-D596

2024

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Medical practice in rural Saskatchewan: factors in physician recruitment and retention

Canadian journal of rural medicine, 2014-06, Vol.19 (3), p.93-98

2014

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Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase

G3 : genes - genomes - genetics, 2021-12, Vol.11 (12)

2021

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Methylation-Sensitive Restriction Enzyme Quantitative Polymerase Chain Reaction Enables Rapid, Accurate, and Precise Detection of Methylation Status of the Regulatory T Cell (Treg)-Specific Demethylation Region in Primary Human Tregs

The Journal of immunology (1950), 2021-01, Vol.206 (2), p.446-451

2021

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Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae

DNA repair, 2009-02, Vol.8 (2), p.162-169

2009

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Abstract 1536: Functional characterization of EDIT-201, a multiplexed CRISPR-Cas12a gene edited healthy donor derived NK cell therapy, reveals increased granzyme B and degranulation supporting improved serial killing capacity

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1536-1536

2021

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Abstract 1532: EDIT-201: CRISPR-Cas12a gene editing enhances functional metabolism of natural killer cells and enables tumor cell cytolysis in metabolically stressful conditions that inhibit effector cell function

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1532-1532

2021

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Preclinical Development of Edit-201, a Multigene Edited Healthy Donor NK Cell with Enhanced Anti-Tumor Function and Superior Serial Killing Activity in an Immunosuppressive Environment

Blood, 2020-11, Vol.136 (Supplement 1), p.33-33

2020

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I-Corps@NCATS trains clinical and translational science teams to accelerate translation of research innovations into practice

Journal of clinical and translational science, 2021-01, Vol.5 (1), p.e66, Article e66

2021

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Generation of Natural Killer Cells with Enhanced Function from a CRISPR/Cas12a-Edited Induced Pluripotent Stem Cell Line

Blood, 2020-11, Vol.136 (Supplement 1), p.8-8

2020

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Perioperative all-cause mortality and cardiovascular events in patients with rheumatoid arthritis: Comparison with unaffected controls and persons with diabetes mellitus

Arthritis & rheumatology (Hoboken, N.J.), 2012-08, Vol.64 (8), p.2429-2437

2012

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Cultivating Perceptions of Farm Culture: Perspectives From the Canadian Prairies

Journal of rural mental health, 2024-04, Vol.48 (2), p.120-131

2024

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Short‐Term Perioperative All‐Cause Mortality and Cardiovascular Events in Women With Systemic Lupus Erythematosus

Arthritis care & research (2010), 2013-06, Vol.65 (6), p.986-991

2013

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Poor 1-Year Outcomes After Percutaneous Coronary Interventions in Systemic Lupus Erythematosus: Report From the National Heart, Lung, and Blood Institute Dynamic Registry

Circulation. Cardiovascular interventions, 2008-12, Vol.1 (3), p.201-208

2008

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Poor 1-year outcomes following percutaneous coronary interventions in systemic lupus erythematosus: Report from the National Heart, Lung and Blood Institute Dynamic Registry

Circulation. Cardiovascular interventions, 2008-12, Vol.1 (3), p.201-208

2008

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AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines

Targeted nonviral delivery of genome editors in vivo

Deletion of CISH and TGFβR2 in iPSC-Derived NK Cells Promotes High Cytotoxicity and Enhances In Vivo Tumor Killing

A Bicistronic Vector Expressing CD16 and a Membrane Bound IL-15 Construct in iPSC Derived NK Cells Increased Cytotoxicity and Persistence

CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes

Medical practice in rural Saskatchewan: factors in physician recruitment and retention

Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase

A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand

Methylation-Sensitive Restriction Enzyme Quantitative Polymerase Chain Reaction Enables Rapid, Accurate, and Precise Detection of Methylation Status of the Regulatory T Cell (Treg)-Specific Demethylation Region in Primary Human Tregs

Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae

Abstract 1536: Functional characterization of EDIT-201, a multiplexed CRISPR-Cas12a gene edited healthy donor derived NK cell therapy, reveals increased granzyme B and degranulation supporting improved serial killing capacity

Abstract 1532: EDIT-201: CRISPR-Cas12a gene editing enhances functional metabolism of natural killer cells and enables tumor cell cytolysis in metabolically stressful conditions that inhibit effector cell function

Preclinical Development of Edit-201, a Multigene Edited Healthy Donor NK Cell with Enhanced Anti-Tumor Function and Superior Serial Killing Activity in an Immunosuppressive Environment

I-Corps@NCATS trains clinical and translational science teams to accelerate translation of research innovations into practice

Generation of Natural Killer Cells with Enhanced Function from a CRISPR/Cas12a-Edited Induced Pluripotent Stem Cell Line

Perioperative all-cause mortality and cardiovascular events in patients with rheumatoid arthritis: Comparison with unaffected controls and persons with diabetes mellitus

Cultivating Perceptions of Farm Culture: Perspectives From the Canadian Prairies

Short‐Term Perioperative All‐Cause Mortality and Cardiovascular Events in Women With Systemic Lupus Erythematosus

Poor 1-Year Outcomes After Percutaneous Coronary Interventions in Systemic Lupus Erythematosus: Report From the National Heart, Lung, and Blood Institute Dynamic Registry

Poor 1-year outcomes following percutaneous coronary interventions in systemic lupus erythematosus: Report from the National Heart, Lung and Blood Institute Dynamic Registry

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