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The APP family of proteins: similarities and differences

Biochemical Society transactions, 2007-04, Vol.35 (Pt 2), p.416-420

2007

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Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Nature medicine, 1996-08, Vol.2 (8), p.864-870

1996

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Nature (London), 1995-06, Vol.375 (6534), p.754-760

1995

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Loss of Ataxin-1 Potentiates Alzheimer’s Pathogenesis by Elevating Cerebral BACE1 Transcription

Cell, 2019-08, Vol.178 (5), p.1159-1175.e17

2019

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Mapping, cloning and genetic characterization of the region containing the Wilson disease gene

Nature genetics, 1993-12, Vol.5 (4), p.338-343

1993

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The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

Nature genetics, 1993-12, Vol.5 (4), p.344-350

1993

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Calsenilin Enhances Apoptosis by Altering Endoplasmic Reticulum Calcium Signaling

Molecular and cellular neuroscience, 2002-04, Vol.19 (4), p.552-559

2002

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Identification of a Mouse Brain cDNA that Encodes a Protein Related to the Alzheimer Disease-Associated Amyloid β Protein Precursor

Proceedings of the National Academy of Sciences - PNAS, 1992-11, Vol.89 (22), p.10758-10762

1992

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The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily

The Journal of biological chemistry, 1994-10, Vol.269 (43), p.26618-26621

1994

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Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3

Molecular and cellular neuroscience, 2003-07, Vol.23 (3), p.495-506

2003

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Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography

Human molecular genetics, 2013-09, Vol.22 (18), p.3798-3806

2013

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Participation of Presenilin 2 in Apoptosis: Enhanced Basal Activity Conferred by an Alzheimer Mutation

Science (American Association for the Advancement of Science), 1996-12, Vol.274 (5293), p.1710-1713

1996

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A novel presenilin-1 mutation: Increased β-amyloid and neurofibrillary changes

Annals of neurology, 1997-06, Vol.41 (6), p.809-813

1997

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Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Science (American Association for the Advancement of Science), 1995-08, Vol.269 (5226), p.973-977

1995

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Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

Nature medicine, 1998-10, Vol.4 (10), p.1177-1181

1998

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γ-Secretase Cleavage and Binding to FE65 Regulate the Nuclear Translocation of the Intracellular C-Terminal Domain (ICD) of the APP Family of Proteins

Biochemistry (Easton), 2003-06, Vol.42 (22), p.6664-6673

2003

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Altered Aβ Formation and Long-Term Potentiation in a Calsenilin Knock-Out

The Journal of neuroscience, 2003-10, Vol.23 (27), p.9097-9106

2003

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Alzheimer-associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells

Nature medicine, 1996-02, Vol.2 (2), p.224-229

1996

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Calcium-regulated DNA Binding and Oligomerization of the Neuronal Calcium-sensing Protein, Calsenilin/DREAM/KChIP3

The Journal of biological chemistry, 2001-11, Vol.276 (44), p.41005-41013

2001

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Endoproteolytic Cleavage and Proteasomal Degradation of Presenilin 2 in Transfected Cells

The Journal of biological chemistry, 1997-04, Vol.272 (17), p.11006-11010

1997

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Nature (London), 1995-06, Vol.375 (6534), p.754-760

1995

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The Amyloid Precursor-like Protein (APLP) Gene Maps to the Long Arm of Human Chromosome 19

Genomics (San Diego, Calif.), 1993, Vol.15 (1), p.237-239

1993

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Calsenilin Reverses Presenilin-Mediated Enhancement of Calcium Signaling

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (15), p.8590-8593

2000

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The gene defects responsible for familial Alzheimer's disease

Neurobiology of disease, 1996-01, Vol.3 (3), p.159-168

1996

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Identification and Characterization of Calmodulin-binding Proteins in Mammalian Sperm Flagella

The Journal of biological chemistry, 1989-03, Vol.264 (9), p.5104-5111

1989

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The APP family of proteins: similarities and differences

Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Loss of Ataxin-1 Potentiates Alzheimer’s Pathogenesis by Elevating Cerebral BACE1 Transcription

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

Calsenilin Enhances Apoptosis by Altering Endoplasmic Reticulum Calcium Signaling

Identification of a Mouse Brain cDNA that Encodes a Protein Related to the Alzheimer Disease-Associated Amyloid β Protein Precursor

The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily

Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3

Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography

Participation of Presenilin 2 in Apoptosis: Enhanced Basal Activity Conferred by an Alzheimer Mutation

A novel presenilin-1 mutation: Increased β-amyloid and neurofibrillary changes

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Calsenilin: A calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

γ-Secretase Cleavage and Binding to FE65 Regulate the Nuclear Translocation of the Intracellular C-Terminal Domain (ICD) of the APP Family of Proteins

Altered Aβ Formation and Long-Term Potentiation in a Calsenilin Knock-Out

Alzheimer-associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells

Calcium-regulated DNA Binding and Oligomerization of the Neuronal Calcium-sensing Protein, Calsenilin/DREAM/KChIP3

Endoproteolytic Cleavage and Proteasomal Degradation of Presenilin 2 in Transfected Cells

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

The Amyloid Precursor-like Protein (APLP) Gene Maps to the Long Arm of Human Chromosome 19

Calsenilin Reverses Presenilin-Mediated Enhancement of Calcium Signaling

The gene defects responsible for familial Alzheimer's disease

Identification and Characterization of Calmodulin-binding Proteins in Mammalian Sperm Flagella

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