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Therapeutic opportunities within the DNA damage response

Nature reviews. Cancer, 2015-03, Vol.15 (3), p.166-180

2015

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Subtype Selective γ‑Aminobutyric Acid Type A Receptor (GABAAR) Modulators Acting at the Benzodiazepine Binding Site: An Update

Journal of medicinal chemistry, 2020-04, Vol.63 (7), p.3425-3446

2020

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AMPA Receptor Positive Allosteric Modulators: Potential for the Treatment of Neuropsychiatric and Neurological Disorders

Current topics in medicinal chemistry, 2016-12, Vol.16 (29), p.3536-3565

2016

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Comprehensive Medicinal Chemistry III

3, 2017

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Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives

Cancers, 2021-05, Vol.13 (10), p.2418

2021

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Epidermal Barrier Dysfunction in Atopic Dermatitis

Journal of investigative dermatology, 2009-08, Vol.129 (8), p.1892-1908

2009

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What does the aromatic ring number mean for drug design?

Expert opinion on drug discovery, 2014-09, Vol.9 (9), p.995-1003

2014

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Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan

Molecular cancer therapeutics, 2015-02, Vol.14 (2), p.575-585

2015

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New perspectives on epidermal barrier dysfunction in atopic dermatitis: Gene–environment interactions

Journal of allergy and clinical immunology, 2006-07, Vol.118 (1), p.3-21

2006

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Recent advances in the discovery of selective AMPA receptor positive allosteric modulators

Current medicinal chemistry, 2010-10, Vol.17 (30), p.3503-3513

2010

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Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2

Biochemical journal, 2016-07, Vol.473 (13), p.1869-1879

2016

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Lung Volume Reduction in Emphysema Improves Chest Wall Asynchrony

Chest, 2015-07, Vol.148 (1), p.185-195

2015

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CCRK is a novel signalling hub exploitable in cancer immunotherapy

Pharmacology & therapeutics (Oxford), 2018-06, Vol.186, p.138-151

2018

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Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5312-5329

2019

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Females Choose Mates Based on Genetic Relatedness in a Small Dasyurid Marsupial, the Agile Antechinus (Antechinus agilis)

PloS one, 2015-04, Vol.10 (4), p.e0122381-e0122381

2015

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Lung function indices for predicting mortality in COPD

The European respiratory journal, 2013-09, Vol.42 (3), p.616-625

2013

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Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11709-11728

2021

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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.3658-3676

2021

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Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer

Bioorganic & medicinal chemistry letters, 2020-04, Vol.30 (8), p.127040, Article 127040

2020

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Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.13705-13713

2022

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Challenges for and current status of research into positive modulators of AMPA receptors

British journal of pharmacology, 2010-05, Vol.160 (2), p.181-190

2010

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Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases

European journal of medicinal chemistry, 2024-04, Vol.269, p.116292-116292, Article 116292

2024

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Central Nervous System Targeted Protein Degraders

Biomolecules (Basel, Switzerland), 2023-07, Vol.13 (8), p.1164

2023

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Protein Identification and Quantification Using Porous Silicon Arrays, Optical Measurements, and Machine Learning

Biosensors (Basel), 2023-09, Vol.13 (9), p.879

2023

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Urban Memory and Visual Culture in Berlin : Framing the Asynchronous City, 1957-2012

Ward, Simon

1, 2016

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Therapeutic opportunities within the DNA damage response

Subtype Selective γ‑Aminobutyric Acid Type A Receptor (GABAAR) Modulators Acting at the Benzodiazepine Binding Site: An Update

AMPA Receptor Positive Allosteric Modulators: Potential for the Treatment of Neuropsychiatric and Neurological Disorders

Comprehensive Medicinal Chemistry III

Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives

Epidermal Barrier Dysfunction in Atopic Dermatitis

What does the aromatic ring number mean for drug design?

Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan

New perspectives on epidermal barrier dysfunction in atopic dermatitis: Gene–environment interactions

Recent advances in the discovery of selective AMPA receptor positive allosteric modulators

Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2

Lung Volume Reduction in Emphysema Improves Chest Wall Asynchrony

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

Females Choose Mates Based on Genetic Relatedness in a Small Dasyurid Marsupial, the Agile Antechinus (Antechinus agilis)

Lung function indices for predicting mortality in COPD

Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors

Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion

Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer

Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity

Challenges for and current status of research into positive modulators of AMPA receptors

Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases

Central Nervous System Targeted Protein Degraders

Protein Identification and Quantification Using Porous Silicon Arrays, Optical Measurements, and Machine Learning

Urban Memory and Visual Culture in Berlin : Framing the Asynchronous City, 1957-2012

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