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TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase–Derived Reactive Oxygen Species Generation in Hypertension

Hypertension (Dallas, Tex. 1979), 2017-05, Vol.69 (5), p.892-901

2017

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Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Circulation (New York, N.Y.), 2012-02, Vol.125 (5), p.697-707

2012

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Marine Compound Xyloketal B as a Potential Drug Development Target for Neuroprotection

Marine drugs, 2018-12, Vol.16 (12), p.516

2018

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WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells

Acta pharmacologica Sinica, 2018-01, Vol.39 (1), p.35-47

2018

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Transmembrane member 16A participates in hydrogen peroxide‐induced apoptosis by facilitating mitochondria‐dependent pathway in vascular smooth muscle cells

British journal of pharmacology, 2018-09, Vol.175 (18), p.3669-3684

2018

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Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway

Marine drugs, 2021-12, Vol.20 (1), p.23

2021

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SGK1 mediates the hypotonic protective effect against H2O2-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway

Acta pharmacologica Sinica, 2020-08, Vol.41 (8), p.1073-1084

2020

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Isaridin E Protects against Sepsis by Inhibiting Von Willebrand Factor-Induced Endothelial Hyperpermeability and Platelet–Endothelium Interaction

Marine drugs, 2024-06, Vol.22 (6), p.283

2024

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Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites

Acta pharmacologica Sinica, 2019-04, Vol.40 (4), p.492-499

2019

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Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo

Acta pharmacologica Sinica, 2018-05, Vol.39 (5), p.858-865

2018

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Threonine532 phosphorylation in ClC‐3 channels is required for angiotensin II‐induced Cl− current and migration in cultured vascular smooth muscle cells

British journal of pharmacology, 2016-02, Vol.173 (3), p.529-544

2016

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Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation

Acta pharmacologica Sinica, 2020-02, Vol.41 (2), p.208-217

2020

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Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells

Circulation Journal, 2016/10/25, Vol.80(11), pp.2397-2406

2016

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Xyloketal B suppresses glioblastoma cell proliferation and migration in vitro through inhibiting TRPM7-regulated PI3K/Akt and MEK/ERK signaling pathways

Marine drugs, 2015-04, Vol.13 (4), p.2505-2525

2015

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Ca2+/Calmodulin-Dependent Protein Kinase II γ-Dependent Serine727 Phosphorylation Is Required for TMEM16A Ca2+-Activated Cl− Channel Regulation in Cerebrovascular Cells

Circulation Journal, 2018/02/23, Vol.82(3), pp.903-913

2018

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Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

Molecular brain, 2019-05, Vol.12 (1), p.50-50, Article 50

2019

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Marine compound xyloketal B reduces neonatal hypoxic-ischemic brain injury

Marine drugs, 2014-12, Vol.13 (1), p.29-47

2014

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Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice

Acta pharmacologica Sinica, 2019-12, Vol.40 (12), p.1532-1543

2019

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Endophilin A2 protects H2O2-induced apoptosis by blockade of Bax translocation in rat basilar artery smooth muscle cells

Journal of molecular and cellular cardiology, 2016-03, Vol.92, p.122-133

2016

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Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pathway and calcium signaling

Acta pharmacologica Sinica, 2018-05, Vol.39 (5), p.875-884

2018

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Involvement of Kv1.5 protein in oxidative vascular endothelial cell injury

PloS one, 2012-11, Vol.7 (11), p.e49758

2012

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Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury

Acta pharmacologica Sinica, 2013-01, Vol.34 (1), p.113-118

2013

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ClC-3 deficiency prevents atherosclerotic lesion development in ApoE−/− mice

Journal of molecular and cellular cardiology, 2015-10, Vol.87, p.237-247

2015

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Protective effects of xyloketal B against MPP+-induced neurotoxicity in Caenorhabditis elegans and PC12 cells

Brain research, 2010-05, Vol.1332, p.110-119

2010

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Xyloketal B: A marine compound with medicinal potential

Pharmacology & therapeutics (Oxford), 2022-02, Vol.230, p.107963-107963, Article 107963

2022

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TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase–Derived Reactive Oxygen Species Generation in Hypertension

Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

Marine Compound Xyloketal B as a Potential Drug Development Target for Neuroprotection

WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells

Transmembrane member 16A participates in hydrogen peroxide‐induced apoptosis by facilitating mitochondria‐dependent pathway in vascular smooth muscle cells

Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway

SGK1 mediates the hypotonic protective effect against H2O2-induced apoptosis of rat basilar artery smooth muscle cells by inhibiting the FOXO3a/Bim signaling pathway

Isaridin E Protects against Sepsis by Inhibiting Von Willebrand Factor-Induced Endothelial Hyperpermeability and Platelet–Endothelium Interaction

Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites

Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo

Threonine532 phosphorylation in ClC‐3 channels is required for angiotensin II‐induced Cl− current and migration in cultured vascular smooth muscle cells

Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation

Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells

Xyloketal B suppresses glioblastoma cell proliferation and migration in vitro through inhibiting TRPM7-regulated PI3K/Akt and MEK/ERK signaling pathways

Ca2+/Calmodulin-Dependent Protein Kinase II γ-Dependent Serine727 Phosphorylation Is Required for TMEM16A Ca2+-Activated Cl− Channel Regulation in Cerebrovascular Cells

Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

Marine compound xyloketal B reduces neonatal hypoxic-ischemic brain injury

Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice

Endophilin A2 protects H2O2-induced apoptosis by blockade of Bax translocation in rat basilar artery smooth muscle cells

Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pathway and calcium signaling

Involvement of Kv1.5 protein in oxidative vascular endothelial cell injury

Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemic injury

ClC-3 deficiency prevents atherosclerotic lesion development in ApoE−/− mice

Protective effects of xyloketal B against MPP+-induced neurotoxicity in Caenorhabditis elegans and PC12 cells

Xyloketal B: A marine compound with medicinal potential

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