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Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor

ACS medicinal chemistry letters, 2018-02, Vol.9 (2), p.143-148

2018

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Potent Long-Acting Inhibitors Targeting the HIV‑1 Capsid Based on a Versatile Quinazolin-4-one Scaffold

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.1941-1954

2023

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Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1708-1729

2014

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The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1730-1752

2014

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P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1853-1859

2018

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Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.8042-8060

2016

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Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (3), p.590-596

2017

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Improved Synthesis of 1-Chloro-6-methoxy-isoquinolin-3-ol and Its Derivatives

Synthetic communications, 2009-03, Vol.39 (7), p.1264-1272

2009

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Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4592-4598

2007

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Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1115-1122

2006

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Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1133-1137

2004

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ChemInform Abstract: Improved Synthesis of 1-Chloro-6-methoxy-isoquinolin-3-ol and Its Derivatives

ChemInform, 2009-09, Vol.40 (37), p.no-no

2009

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Sedimentary Records of DDT and HCH in the Pearl River Delta, South China

Environmental science & technology, 2002-09, Vol.36 (17), p.3671-3677

2002

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Abstract 13483: Peptide Inhibition of PTEN Improves Metabolic Recovery and Outcomes in a Murine Cardiac Arrest Model

Circulation (New York, N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A13483-A13483

2015

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Abstract 17773: Peptide Inhibition of PTEN Increases Mouse Survival after Sudden Cardiac Arrest

Circulation (New York, N.Y.), 2014-11, Vol.130 (suppl_2)

2014

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Abstract 13557: Regulation of PBEF Release by NAD Glycohydrolase CD38

Circulation (New York, N.Y.), 2015-11, Vol.132 (Suppl_3 Suppl 3), p.A13557-A13557

2015

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A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest

American journal of physiology. Heart and circulatory physiology, 2015-06, Vol.308 (11), p.H1414-H1422

2015

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Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells

Journal of inflammation (London, England), 2010-05, Vol.7 (1), p.26-26, Article 26

2010

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Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β2-Integrin Adhesion

American journal of respiratory cell and molecular biology, 2008-09, Vol.39 (3), p.263-269

2008

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Abstract 18534: TAT-Protein Blockade of PTEN After Cardiac Ischemia is Highly Protective

Circulation (New York, N.Y.), 2013-11, Vol.128 (suppl_22)

2013

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Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after [beta]^sub 2^-Integrin Adhesion

American journal of respiratory cell and molecular biology, 2008-09, Vol.39 (3), p.263

2008

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Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β 2 -Integrin Adhesion

American journal of respiratory cell and molecular biology, 2008-09, Vol.39 (3), p.263-269

2008

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Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion

American journal of respiratory cell and molecular biology, 2008-09, Vol.39 (3), p.263-269

2008

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Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor

Potent Long-Acting Inhibitors Targeting the HIV‑1 Capsid Based on a Versatile Quinazolin-4-one Scaffold

Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor

Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing

Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus

Improved Synthesis of 1-Chloro-6-methoxy-isoquinolin-3-ol and Its Derivatives

Respiratory syncytial virus fusion inhibitors. Part 5: Optimization of benzimidazole substitution patterns towards derivatives with improved activity

Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo

Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives

ChemInform Abstract: Improved Synthesis of 1-Chloro-6-methoxy-isoquinolin-3-ol and Its Derivatives

Sedimentary Records of DDT and HCH in the Pearl River Delta, South China

Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci

Correction: Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci

Abstract 13483: Peptide Inhibition of PTEN Improves Metabolic Recovery and Outcomes in a Murine Cardiac Arrest Model

Abstract 17773: Peptide Inhibition of PTEN Increases Mouse Survival after Sudden Cardiac Arrest

Abstract 13557: Regulation of PBEF Release by NAD Glycohydrolase CD38

A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest

Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells

Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β2-Integrin Adhesion

Abstract 18534: TAT-Protein Blockade of PTEN After Cardiac Ischemia is Highly Protective

Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after [beta]^sub 2^-Integrin Adhesion

Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β 2 -Integrin Adhesion

Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion

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