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Protective hinge in insulin opens to enable its receptor engagement

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (33), p.E3395-E3404

2014

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Dramatic increases in blood glutamate concentrations are closely related to traumatic brain injury-induced acute lung injury

Scientific reports, 2017-07, Vol.7 (1), p.5380-9, Article 5380

2017

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A Single Mutation Increases the Thermostability and Activity of Aspergillus terreus Amine Transaminase

Molecules (Basel, Switzerland), 2019-03, Vol.24 (7), p.1194

2019

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Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering

Annals of the New York Academy of Sciences, 2011-12, Vol.1243 (1), p.E40-E54

2011

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Linear dichroism transition and polarization-sensitive photodetector of quasi-one-dimensional palladium bromide

Chinese physics B, 2024-05, Vol.33 (6), p.68101

2024

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Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design

The Journal of biological chemistry, 2014-12, Vol.289 (50), p.34709-34727

2014

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Improving thermostability of (R)-selective amine transaminase from Aspergillus terreus by evolutionary coupling saturation mutagenesis

Biochemical engineering journal, 2021-03, Vol.167, p.107926, Article 107926

2021

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Open Mind Common Sense: Knowledge acquisition from the general public

Lecture notes in computer science, 2002, p.1223-1237

2002

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Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.11755-11759

2010

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Aromatic Anchor at an Invariant Hormone-Receptor Interface

The Journal of biological chemistry, 2014-12, Vol.289 (50), p.34709-34727

2014

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Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery: AN ELECTROSTATIC BLOCK TO THE TR TRANSITION

The Journal of biological chemistry, 2008-07, Vol.283 (30), p.21198-21210

2008

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Chiral Mutagenesis of Insulin. Foldability and Function Are Inversely Regulated by a Stereospecific Switch in the B Chain

Biochemistry (Easton), 2005-04, Vol.44 (13), p.4984-4999

2005

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Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice

Zhēncì yánjiū, 2019-04, Vol.44 (4), p.235

2019

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Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

Biochemistry (Easton), 2005-04, Vol.44 (13), p.5000-5016

2005

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Nasopharyngeal carcinoma incidence and mortality in China, 2013

Ai zheng, 2017-11, Vol.36 (12), p.686-693, Article 90

2017

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Yangzheng Sanjie decoction regulates proliferation and apoptosis of gastric cancer cells by enhancing let-7a expression

World journal of gastroenterology : WJG, 2017-08, Vol.23 (30), p.5538-5548

2017

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The Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery

The Journal of biological chemistry, 2008-07, Vol.283 (30), p.21198-21210

2008

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Crystal Structure of a “Nonfoldable” Insulin

The Journal of biological chemistry, 2009-12, Vol.284 (50), p.35259-35272

2009

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Design of an Insulin Analog with Enhanced Receptor Binding Selectivity

The Journal of biological chemistry, 2009-11, Vol.284 (46), p.32178-32187

2009

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Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding

Biochemistry (Easton), 2003-11, Vol.42 (44), p.12770-12783

2003

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Crystallization and preliminary X-ray studies of allophycocyanin from red alga Porphyra yezoensis

Acta crystallographica. Section D, Biological crystallography., 1998-07, Vol.54 (4), p.662-664

1998

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Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1

Acta pharmacologica Sinica, 2011-04, Vol.32 (4), p.503-511

2011

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Mapping the Information Trace in Local Field Potentials by a Computational Method of Two-Dimensional Time-Shifting Synchronization Likelihood Based on Graphic Processing Unit Acceleration

Neuroscience bulletin, 2017-12, Vol.33 (6), p.653-663

2017

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Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity

The Journal of biological chemistry, 2009-12, Vol.284 (50), p.35259-35272

2009

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A proposed interaction model of the insulin molecule with its receptor

Biophysical chemistry, 1994-05, Vol.50 (1), p.63-71

1994

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Protective hinge in insulin opens to enable its receptor engagement

Dramatic increases in blood glutamate concentrations are closely related to traumatic brain injury-induced acute lung injury

A Single Mutation Increases the Thermostability and Activity of Aspergillus terreus Amine Transaminase

Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering

Linear dichroism transition and polarization-sensitive photodetector of quasi-one-dimensional palladium bromide

Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design

Improving thermostability of (R)-selective amine transaminase from Aspergillus terreus by evolutionary coupling saturation mutagenesis

Open Mind Common Sense: Knowledge acquisition from the general public

Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

Aromatic Anchor at an Invariant Hormone-Receptor Interface

Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery: AN ELECTROSTATIC BLOCK TO THE TR TRANSITION

Chiral Mutagenesis of Insulin. Foldability and Function Are Inversely Regulated by a Stereospecific Switch in the B Chain

Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice

Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama

Nasopharyngeal carcinoma incidence and mortality in China, 2013

Yangzheng Sanjie decoction regulates proliferation and apoptosis of gastric cancer cells by enhancing let-7a expression

The Structure of a Mutant Insulin Uncouples Receptor Binding from Protein Allostery

Crystal Structure of a “Nonfoldable” Insulin

Design of an Insulin Analog with Enhanced Receptor Binding Selectivity

Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding

Crystallization and preliminary X-ray studies of allophycocyanin from red alga Porphyra yezoensis

Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1

Mapping the Information Trace in Local Field Potentials by a Computational Method of Two-Dimensional Time-Shifting Synchronization Likelihood Based on Graphic Processing Unit Acceleration

Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity

A proposed interaction model of the insulin molecule with its receptor

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