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RAF-MEK-ERK pathway in cancer evolution and treatment

Seminars in cancer biology, 2022-10, Vol.85, p.123-154

2022

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Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441)

2019

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K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling

Nature communications, 2019-04, Vol.10 (1), p.1870-15, Article 1870

2019

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FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4881-4893

2017

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Compilation of Dictionaries and Scientific and Technological Translations by Western Protestant Missionaries in China in the Nineteenth Century

Religions (Basel, Switzerland ), 2024-05, Vol.15 (5), p.628

2024

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Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

Biochimica et biophysica acta, 2014-04, Vol.1845 (2), p.277-293

2014

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ITCH as a potential therapeutic target in human cancers

Seminars in cancer biology, 2020-12, Vol.67 (Pt 2), p.117-130

2020

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Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Cell death & disease, 2021-03, Vol.12 (4), p.325-325, Article 325

2021

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Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

Cell research, 2021-01, Vol.31 (1), p.80-93

2021

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Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Journal of experimental & clinical cancer research, 2022-02, Vol.41 (1), p.76-76, Article 76

2022

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Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

Molecular cell, 2018-01, Vol.69 (2), p.279-291.e5

2018

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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Nature (London), 2014-04, Vol.508 (7497), p.541-545

2014

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Tumor suppressor functions of FBW7 in cancer development and progression

FEBS letters, 2012-05, Vol.586 (10), p.1409-1418

2012

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Comparison of Helicobacter pylori positive and negative gastric cancer via multi-omics analysis

mBio, 2023-12, Vol.14 (6), p.e0153123

2023

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Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

Cell, 2014-04, Vol.157 (3), p.595-610

2014

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SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis

Nature communications, 2018-09, Vol.9 (1), p.1-12, Article 3569

2018

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A covalently bound inhibitor triggers EZH2 degradation through CHIP‐mediated ubiquitination

The EMBO journal, 2017-05, Vol.36 (9), p.1243-1260

2017

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The association between composite dietary antioxidant index and the metabolic syndrome: NHANES 2007–2018

Journal of functional foods, 2024-05, Vol.116, p.106200, Article 106200

2024

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HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Cancer research (Chicago, Ill.), 2019-06, Vol.79 (11), p.2947-2961

2019

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Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism

Nature communications, 2018-01, Vol.9 (1), p.159-9, Article 159

2018

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Cdc20: a potential novel therapeutic target for cancer treatment

Current pharmaceutical design, 2013, Vol.19 (18), p.3210-3214

2013

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An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level

PLoS computational biology, 2024-02, Vol.20 (2), p.e1011873-e1011873

2024

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Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

Nature communications, 2019-08, Vol.10 (1), p.3716-15, Article 3716

2019

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The protective role of DOT1L in UV-induced melanomagenesis

Nature communications, 2018-01, Vol.9 (1), p.259-13, Article 259

2018

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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

Molecular cell, 2013-08, Vol.51 (4), p.409-422

2013

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RAF-MEK-ERK pathway in cancer evolution and treatment

Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling

FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A

Compilation of Dictionaries and Scientific and Technological Translations by Western Protestant Missionaries in China in the Nineteenth Century

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

ITCH as a potential therapeutic target in human cancers

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Tumor suppressor functions of FBW7 in cancer development and progression

Comparison of Helicobacter pylori positive and negative gastric cancer via multi-omics analysis

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis

A covalently bound inhibitor triggers EZH2 degradation through CHIP‐mediated ubiquitination

The association between composite dietary antioxidant index and the metabolic syndrome: NHANES 2007–2018

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism

Cdc20: a potential novel therapeutic target for cancer treatment

An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level

Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis

The protective role of DOT1L in UV-induced melanomagenesis

MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

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