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Structure−Activity Relationships for a Series of Quinoline-Based Compounds Active against Replicating and Nonreplicating Mycobacterium tuberculosis

Journal of medicinal chemistry, 2009-04, Vol.52 (7), p.2109-2118

2009

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Low-Oxygen-Recovery Assay for High-Throughput Screening of Compounds against Nonreplicating Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2007-04, Vol.51 (4), p.1380-1385

2007

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Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening

Journal of antibiotics, 2019-10, Vol.72 (10), p.719-728

2019

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5-tert-Butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide Derivatives as Novel Potent Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase: Initiating a Quest for New Antitubercular Drugs

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.1999-2002

2008

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Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis

Journal of antimicrobial chemotherapy, 2012-02, Vol.67 (2), p.415-421

2012

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Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3551-3563

2011

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Chemical Diversity and Antimicrobial Potential of Cultivable Fungi from Deep-Sea Sediments of the Gulf of Mexico

Molecules (Basel, Switzerland), 2021-12, Vol.26 (23), p.7328

2021

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Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models

PloS one, 2013-05, Vol.8 (5), p.e63240

2013

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From Serendipity to Rational Antituberculosis Drug Discovery of Mefloquine-Isoxazole Carboxylic Acid Esters

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.6966-6978

2009

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Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives

Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1402

2018

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Synthesis and antimycobacterial activities of non-purine analogs of 6-aryl-9-benzylpurines: Imidazopyridines, pyrrolopyridines, benzimidazoles, and indoles

Bioorganic & medicinal chemistry, 2011-06, Vol.19 (11), p.3483-3491

2011

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Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1263-1268

2010

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Searching for New Cures for Tuberculosis: Design, Synthesis, and Biological Evaluation of 2-Methylbenzothiazoles

Journal of medicinal chemistry, 2009-11, Vol.52 (21), p.6757-6767

2009

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Anti- Mycobacterium tuberculosis Activity of Esters of Quinoxaline 1,4-Di- N -Oxide

Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1453

2018

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Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring

Bioorganic & medicinal chemistry, 2010-10, Vol.18 (20), p.7274-7282

2010

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Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea

European journal of medicinal chemistry, 2017-01, Vol.125, p.825-841

2017

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Novel thiolactone–isatin hybrids as potential antimalarial and antitubercular agents

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (7), p.2055-2058

2011

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Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa

European journal of medicinal chemistry, 2011-07, Vol.46 (7), p.3118-3123

2011

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Structure–activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy- d-xylulose 5-phosphate synthase

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (19), p.5320-5323

2008

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Synthesis and structure–activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (20), p.6094-6099

2011

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Natural product leads for drug discovery: Isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3- a]carbazole based ligands as antibacterial agents

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7126-7130

2009

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Syntheses and studies of quinolone-cephalosporins as potential anti-tuberculosis agents

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5534-5537

2006

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Design, synthesis and evaluation of diarylpiperazine derivatives as potent anti-tubercular agents

European journal of medicinal chemistry, 2015-11, Vol.105, p.238-244

2015

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Design, synthesis and investigation on the structure–activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents

European journal of medicinal chemistry, 2014-01, Vol.72, p.26-34

2014

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Modification of the side chain of micromolide, an anti-tuberculosis natural product

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (19), p.5311-5315

2008

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Structure−Activity Relationships for a Series of Quinoline-Based Compounds Active against Replicating and Nonreplicating Mycobacterium tuberculosis

Low-Oxygen-Recovery Assay for High-Throughput Screening of Compounds against Nonreplicating Mycobacterium tuberculosis

Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening

5-tert-Butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide Derivatives as Novel Potent Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase: Initiating a Quest for New Antitubercular Drugs

Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis

Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1

Chemical Diversity and Antimicrobial Potential of Cultivable Fungi from Deep-Sea Sediments of the Gulf of Mexico

Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models

From Serendipity to Rational Antituberculosis Drug Discovery of Mefloquine-Isoxazole Carboxylic Acid Esters

Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives

Synthesis and antimycobacterial activities of non-purine analogs of 6-aryl-9-benzylpurines: Imidazopyridines, pyrrolopyridines, benzimidazoles, and indoles

Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs

Searching for New Cures for Tuberculosis: Design, Synthesis, and Biological Evaluation of 2-Methylbenzothiazoles

Anti- Mycobacterium tuberculosis Activity of Esters of Quinoxaline 1,4-Di- N -Oxide

Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring

Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea

Novel thiolactone–isatin hybrids as potential antimalarial and antitubercular agents

Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa

Structure–activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy- d-xylulose 5-phosphate synthase

Synthesis and structure–activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin

Natural product leads for drug discovery: Isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3- a]carbazole based ligands as antibacterial agents

Syntheses and studies of quinolone-cephalosporins as potential anti-tuberculosis agents

Design, synthesis and evaluation of diarylpiperazine derivatives as potent anti-tubercular agents

Design, synthesis and investigation on the structure–activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents

Modification of the side chain of micromolide, an anti-tuberculosis natural product

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