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Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease

Physiological reviews, 2004-07, Vol.84 (3), p.767-801

2004

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Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease

Scientific reports, 2019-08, Vol.9 (1), p.12541-14, Article 12541

2019

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Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk

PloS one, 2023-09, Vol.18 (9), p.e0291330

2023

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Complex Regulation and Function of the Inflammatory Smooth Muscle Cell Phenotype in Atherosclerosis

Journal of vascular research, 2010-01, Vol.47 (2), p.168-180

2010

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Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5)

American Journal of Physiology: Cell Physiology, 2012-01, Vol.302 (1), p.C1-C8

2012

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Excitation–Transcription Coupling in Arterial Smooth Muscle

Circulation research, 2006-04, Vol.98 (7), p.868-878

2006

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Chromatin immunoprecipitation (ChIP): revisiting the efficacy of sample preparation, sonication, quantification of sheared DNA, and analysis via PCR

PloS one, 2011-10, Vol.6 (10), p.e26015-e26015

2011

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Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming

American Journal of Physiology: Cell Physiology, 2007-12, Vol.293 (6), p.C1824-C1833

2007

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Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype

Arteriosclerosis, thrombosis, and vascular biology, 2008-08, Vol.28 (8), p.1454-1461

2008

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Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response

Scientific reports, 2021-03, Vol.11 (1), p.5535-5535, Article 5535

2021

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Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker Genes

Circulation research, 2003-05, Vol.92 (8), p.856-864

2003

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Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis

JHEP reports, 2021-04, Vol.3 (2), p.100217-100217, Article 100217

2021

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Exposure of Induced Pluripotent Stem Cell‐Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell‐Like Phenotypes

Stem cells translational medicine, 2017-08, Vol.6 (8), p.1673-1683

2017

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Discovery, Biological Evaluation, and Structure−Activity Relationship of Amidine Based Sphingosine Kinase Inhibitors

Journal of medicinal chemistry, 2010-04, Vol.53 (7), p.2766-2778

2010

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The Smooth Muscle Cell-restricted KCNMB1 Ion Channel Subunit Is a Direct Transcriptional Target of Serum Response Factor and Myocardin

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33671-33682

2009

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NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration

Frontiers in physiology, 2012-01, Vol.3, p.313-313

2012

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PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

American journal of physiology. Heart and circulatory physiology, 2009-02, Vol.296 (2), p.H442-H452

2009

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Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report

Arteriosclerosis, thrombosis, and vascular biology, 2011-12, Vol.31 (12), p.2853-2855

2011

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Non-alcoholic fatty liver disease (NAFLD) models in drug discovery

Expert opinion on drug discovery, 2018-02, Vol.13 (2), p.193-205

2018

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Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

Circulation research, 2010-09, Vol.107 (6), p.737-746

2010

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Drug-induced steatohepatitis

Expert opinion on drug metabolism & toxicology, 2017-02, Vol.13 (2), p.193-204

2017

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Focused in vivo Delivery of Plasmid DNA to the Porcine Vascular Wall via Intravascular Ultrasound Destruction of Microbubbles

Journal of vascular research, 2010-01, Vol.47 (3), p.270-274

2010

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Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes

Molecular genetics and metabolism, 2020-07, Vol.130 (3), p.183-196

2020

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Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.5037-5048

2021

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A novel small molecule approach for the treatment of propionic and methylmalonic acidemias

Molecular genetics and metabolism, 2021-05, Vol.133 (1), p.71-82

2021

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Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease

Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease

Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk

Complex Regulation and Function of the Inflammatory Smooth Muscle Cell Phenotype in Atherosclerosis

Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5)

Excitation–Transcription Coupling in Arterial Smooth Muscle

Chromatin immunoprecipitation (ChIP): revisiting the efficacy of sample preparation, sonication, quantification of sheared DNA, and analysis via PCR

Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming

Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype

Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response

Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker Genes

Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis

Exposure of Induced Pluripotent Stem Cell‐Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell‐Like Phenotypes

Discovery, Biological Evaluation, and Structure−Activity Relationship of Amidine Based Sphingosine Kinase Inhibitors

The Smooth Muscle Cell-restricted KCNMB1 Ion Channel Subunit Is a Direct Transcriptional Target of Serum Response Factor and Myocardin

NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration

PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report

Non-alcoholic fatty liver disease (NAFLD) models in drug discovery

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

Drug-induced steatohepatitis

Focused in vivo Delivery of Plasmid DNA to the Porcine Vascular Wall via Intravascular Ultrasound Destruction of Microbubbles

Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes

Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia

A novel small molecule approach for the treatment of propionic and methylmalonic acidemias

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