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NAADP: From Discovery to Mechanism

Frontiers in immunology, 2021-09, Vol.12, p.703326-703326

2021

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Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells

The Journal of biological chemistry, 2012-01, Vol.287 (4), p.2296-2307

2012

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Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (36), p.13087-13092

2014

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Role of CD38/cADPR signaling in obstructive pulmonary diseases

Current opinion in pharmacology, 2020-04, Vol.51, p.29-33

2020

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Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

The Journal of biological chemistry, 2012-01, Vol.287 (4), p.2308-2315

2012

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MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells

Respiratory research, 2014-08, Vol.15 (1), p.107-107, Article 107

2014

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CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

Mediators of inflammation, 2018-01, Vol.2018 (2018), p.1-10

2018

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Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells Is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction

The Journal of immunology (1950), 2007-12, Vol.179 (11), p.7827-7839

2007

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CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models

Canadian journal of physiology and pharmacology, 2015-02, Vol.93 (2), p.145-153

2015

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NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

Cell calcium (Edinburgh), 2018-11, Vol.75, p.30-41

2018

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HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

Journal of neuroinflammation, 2011-10, Vol.8 (1), p.145-145, Article 145

2011

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Identification of a dihydropyridine scaffold that blocks ryanodine receptors

iScience, 2022-01, Vol.25 (1), p.103706-103706, Article 103706

2022

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CD38 regulation in activated astrocytes: Implications for neuroinflammation and HIV-1 brain infection

Journal of neuroscience research, 2009-08, Vol.87 (10), p.2326-2339

2009

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CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle

American journal of physiology. Lung cellular and molecular physiology, 2005-05, Vol.288 (5), p.L773-L788

2005

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CD38/cADPR-mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1

IUBMB life, 2024-08

2024

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Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

The EMBO journal, 2015-07, Vol.34 (13), p.1743-1758

2015

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Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12

Science signaling, 2023-08, Vol.16 (799), p.eadg0485

2023

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Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105378-105378, Article 105378

2023

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Synthesis and biological evaluation of novel photo-clickable adenosine and cyclic ADP-ribose analogs: 8-N3-2′-O-propargyladenosine and 8-N3-2′-O-propargyl-cADPR

Bioorganic & medicinal chemistry, 2022-12, Vol.76, p.117099-117099, Article 117099

2022

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5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors

Biochimica et biophysica acta. Molecular cell research, 2019-07, Vol.1866 (7), p.1180-1188

2019

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Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins

ACS chemical biology, 2024-08, Vol.19 (8), p.1842-1849

2024

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Intracellular calcium signaling through the CADPR pathway is agonist specific in porcine airway smooth muscle

The FASEB journal, 2003-03, Vol.17 (3), p.1-19

2003

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The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate

Science signaling, 2019-01, Vol.12 (566)

2019

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Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1

American journal of physiology. Lung cellular and molecular physiology, 2008-07, Vol.295 (1), p.L186-L193

2008

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Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone

Respiratory research, 2008-03, Vol.9 (1), p.26-26, Article 26

2008

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NAADP: From Discovery to Mechanism

Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells

Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

Role of CD38/cADPR signaling in obstructive pulmonary diseases

Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells

CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells Is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction

CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models

NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

Identification of a dihydropyridine scaffold that blocks ryanodine receptors

CD38 regulation in activated astrocytes: Implications for neuroinflammation and HIV-1 brain infection

CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle

CD38/cADPR-mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1

Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12

Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum

Synthesis and biological evaluation of novel photo-clickable adenosine and cyclic ADP-ribose analogs: 8-N3-2′-O-propargyladenosine and 8-N3-2′-O-propargyl-cADPR

5-Azido-8-ethynyl-NAADP: A bifunctional, clickable photoaffinity probe for the identification of NAADP receptors

Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins

Intracellular calcium signaling through the CADPR pathway is agonist specific in porcine airway smooth muscle

The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate

Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone

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