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Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

Nature reviews. Drug discovery, 2015-05, Vol.14 (5), p.329-345

2015

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Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

Physiological reviews, 2008-10, Vol.88 (4), p.1547-1565

Wallace, John L

2008

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Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy

World journal of gastroenterology : WJG, 2013-03, Vol.19 (12), p.1861-1876

Wallace, John L

2013

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NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies

British journal of pharmacology, 2012-01, Vol.165 (1), p.67-74

Wallace, John L

2012

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Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract

Antioxidants & redox signaling, 2010-05, Vol.12 (9), p.1125-1133

Wallace, John L

2010

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Anti-inflammatory and cytoprotective properties of hydrogen sulfide

Methods in enzymology, 2015, Vol.555, p.169-193

2015

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Synthesis and Biological Effects of Hydrogen Sulfide (H2S): Development of H2S-Releasing Drugs as Pharmaceuticals

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6275-6286

2010

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A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

British journal of pharmacology, 2020-02, Vol.177 (4), p.769-777

2020

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Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments

American journal of physiology: Gastrointestinal and liver physiology, 2013-10, Vol.305 (7), p.G467-G473

2013

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Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis

Gastroenterology (New York, N.Y. 1943), 2011-10, Vol.141 (4), p.1314-1322.e5

2011

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Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production

Inflammatory bowel diseases, 2015-05, Vol.21 (5), p.1006-1017

2015

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Anti-inflammatory effect of ATB-352, a H2S −releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats

Pharmacological research, 2018-06, Vol.132, p.220-231

2018

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Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism

PloS one, 2013-08, Vol.8 (8), p.e71962

2013

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Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence

PloS one, 2012-04, Vol.7 (4), p.e35196

2012

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Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (2), p.434-439

2016

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Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease

PloS one, 2017-06, Vol.12 (6), p.e0178647-e0178647

2017

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Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics

Antioxidants & redox signaling, 2015-02, Vol.22 (5), p.398-410

2015

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Gastrointestinal Safety and Anti-Inflammatory Effects of a Hydrogen Sulfide–Releasing Diclofenac Derivative in the Rat

Gastroenterology (New York, N.Y. 1943), 2007, Vol.132 (1), p.261-271

2007

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NSAID-gastroenteropathy: new aspects of pathogenesis and prevention

Current opinion in pharmacology, 2014-12, Vol.19, p.11-16

2014

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Gaseous Mediators as a Key Molecular Targets for the Development of Gastrointestinal-Safe Anti-Inflammatory Pharmacology

Frontiers in pharmacology, 2021-04, Vol.12, p.657457-657457

2021

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Cytoprotective effects of hydrogen sulfide in novel rat models of non-erosive esophagitis

PloS one, 2014-10, Vol.9 (10), p.e110688

2014

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Nitric oxide in the gastrointestinal tract: opportunities for drug development

British journal of pharmacology, 2019-01, Vol.176 (2), p.147-154

Wallace, John L

2019

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Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (37), p.13559-13564

2014

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Active thrombin produced by the intestinal epithelium controls mucosal biofilms

Nature communications, 2019-07, Vol.10 (1), p.3224-12, Article 3224

2019

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NSAID enteropathy and bacteria: a complicated relationship

Journal of gastroenterology, 2015-04, Vol.50 (4), p.387-393

2015

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Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy

NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies

Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract

Anti-inflammatory and cytoprotective properties of hydrogen sulfide

Synthesis and Biological Effects of Hydrogen Sulfide (H2S): Development of H2S-Releasing Drugs as Pharmaceuticals

A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug

Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments

Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis

Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production

Anti-inflammatory effect of ATB-352, a H2S −releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats

Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism

Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence

Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways

Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease

Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics

Gastrointestinal Safety and Anti-Inflammatory Effects of a Hydrogen Sulfide–Releasing Diclofenac Derivative in the Rat

NSAID-gastroenteropathy: new aspects of pathogenesis and prevention

Gaseous Mediators as a Key Molecular Targets for the Development of Gastrointestinal-Safe Anti-Inflammatory Pharmacology

Cytoprotective effects of hydrogen sulfide in novel rat models of non-erosive esophagitis

Nitric oxide in the gastrointestinal tract: opportunities for drug development

Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis

Active thrombin produced by the intestinal epithelium controls mucosal biofilms

NSAID enteropathy and bacteria: a complicated relationship

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