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Novel tactics for designing water-soluble molecules in drug discovery

Expert opinion on drug discovery, 2014-12, Vol.9 (12), p.1421-1433

Walker, Michael A

2014

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Overexpression of 9- cis -Epoxycarotenoid Dioxygenase Cisgene in Grapevine Increases Drought Tolerance and Results in Pleiotropic Effects

Frontiers in plant science, 2018-08, Vol.9, p.970-970

2018

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Embodying Dialogue: Teaching Disability and Ability in a Time of Crisis

Journal of feminist studies in religion, 2020-03, Vol.36 (1), p.167-169

Walker, Michael A. “Mike”

2020

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Tandem Ring-Closing Metathesis/Transfer Hydrogenation: Practical Chemoselective Hydrogenation of Alkenes

Organic letters, 2014-09, Vol.16 (17), p.4444-4447

2014

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Improvement in aqueous solubility achieved via small molecular changes

Bioorganic & medicinal chemistry letters, 2017-12, Vol.27 (23), p.5100-5108

Walker, Michael A.

2017

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The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

Pharmacology & therapeutics (Oxford), 2013-08, Vol.139 (2), p.213-248

2013

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Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.717-720

2015

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Persistent Pain and Promised Perfection:The Significance of an Embodied Eschatologyof Disability

Journal of disability & religion, 2023-01, Vol.27 (1), p.108-123

Walker, Michael A.

2023

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Low-event-rate meta-analyses of clinical trials: implementing good practices

Statistics in medicine, 2016-06, Vol.35 (14), p.2467-2478

2016

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Changes to the HIV Long Terminal Repeat and to HIV Integrase Differentially Impact HIV Integrase Assembly, Activity, and the Binding of Strand Transfer Inhibitors

The Journal of biological chemistry, 2007-10, Vol.282 (43), p.31186-31196

2007

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Preclinical characterization of ABI-H2158, an HBV core inhibitor with dual mechanisms of action

Antiviral research, 2023-01, Vol.209, p.105485, Article 105485

2023

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Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

The lancet respiratory medicine, 2013-11, Vol.1 (9), p.714-727

2013

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Biochemical Analysis of HIV-1 Integrase Variants Resistant to Strand Transfer Inhibitors

The Journal of biological chemistry, 2008-08, Vol.283 (35), p.23599-23609

2008

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Caring and Covenant: Notes on a Sacramental Ecclesiology of Disability

Journal of disability & religion, 2019-04, Vol.23 (2), p.166-177

Walker, Michael A.

2019

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5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1348-1361

2019

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Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV‑1 Integrase Inhibitors

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.2620-2637

2020

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A High Yielding Synthesis of N-Alkyl Maleimides Using a Novel Modification of the Mitsunobu Reaction

Journal of organic chemistry, 1995-08, Vol.60 (16), p.5352-5355

Walker, Michael A

1995

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Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry, 2020-07, Vol.28 (13), p.115541-115541, Article 115541

2020

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Utilizing (Al, Ga)2O3/Ga2O3 superlattices to measure cation vacancy diffusion and vacancy-concentration-dependent diffusion of Al, Sn, and Fe in β-Ga2O3

APL materials, 2024-08, Vol.12 (8), p.081101-081101-11

2024

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Synthesis and Biological Studies of Novel 2-Aminoalkylethers as Potential Antiarrhythmic Agents for the Conversion of Atrial Fibrillation

Journal of medicinal chemistry, 2007-06, Vol.50 (12), p.2818-2841

2007

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Evaluation of the association between spondylosis deformans and clinical signs of intervertebral disk disease in dogs: 172 cases (1999-2000)

Journal of the American Veterinary Medical Association, 2006-01, Vol.228 (1), p.96-100

2006

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Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (3), p.126784, Article 126784

2020

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Discovery and Preclinical Profiling of GSK3839919, a Potent HIV‑1 Allosteric Integrase Inhibitor

ACS medicinal chemistry letters, 2022-06, Vol.13 (6), p.972-980

2022

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The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor

Bioorganic & medicinal chemistry letters, 2018-07, Vol.28 (12), p.2124-2130

2018

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New first and second generation inhibitors of human immunodeficiency virus-1 integrase

Expert opinion on therapeutic patents, 2011-08, Vol.21 (8), p.1173-1189

2011

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Novel tactics for designing water-soluble molecules in drug discovery

Overexpression of 9- cis -Epoxycarotenoid Dioxygenase Cisgene in Grapevine Increases Drought Tolerance and Results in Pleiotropic Effects

Embodying Dialogue: Teaching Disability and Ability in a Time of Crisis

Tandem Ring-Closing Metathesis/Transfer Hydrogenation: Practical Chemoselective Hydrogenation of Alkenes

Improvement in aqueous solubility achieved via small molecular changes

The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors

Persistent Pain and Promised Perfection:The Significance of an Embodied Eschatologyof Disability

Low-event-rate meta-analyses of clinical trials: implementing good practices

Changes to the HIV Long Terminal Repeat and to HIV Integrase Differentially Impact HIV Integrase Assembly, Activity, and the Binding of Strand Transfer Inhibitors

Preclinical characterization of ABI-H2158, an HBV core inhibitor with dual mechanisms of action

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

Biochemical Analysis of HIV-1 Integrase Variants Resistant to Strand Transfer Inhibitors

Caring and Covenant: Notes on a Sacramental Ecclesiology of Disability

5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors

Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV‑1 Integrase Inhibitors

A High Yielding Synthesis of N-Alkyl Maleimides Using a Novel Modification of the Mitsunobu Reaction

Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors

Utilizing (Al, Ga)2O3/Ga2O3 superlattices to measure cation vacancy diffusion and vacancy-concentration-dependent diffusion of Al, Sn, and Fe in β-Ga2O3

Synthesis and Biological Studies of Novel 2-Aminoalkylethers as Potential Antiarrhythmic Agents for the Conversion of Atrial Fibrillation

Evaluation of the association between spondylosis deformans and clinical signs of intervertebral disk disease in dogs: 172 cases (1999-2000)

Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors

Discovery and Preclinical Profiling of GSK3839919, a Potent HIV‑1 Allosteric Integrase Inhibitor

The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor

New first and second generation inhibitors of human immunodeficiency virus-1 integrase

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