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Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (21), p.10557-10562

2019

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Nature communications, 2022-11, Vol.13 (1), p.7131-7131, Article 7131

2022

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A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

Frontiers in pharmacology, 2021-06, Vol.12, p.685308-685308

2021

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Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Communications chemistry, 2024-04, Vol.7 (1), p.84-84, Article 84

2024

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Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors

Accounts of chemical research, 2021-02, Vol.54 (4), p.930-939

2021

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A Synthetic ERR Agonist Alleviates Metabolic Syndrome

The Journal of pharmacology and experimental therapeutics, 2024-02, Vol.388 (2), p.232-240

2024

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Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold

Biochimica et biophysica acta. General subjects, 2020-06, Vol.1864 (6), p.129546-129546, Article 129546

2020

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Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804

Biochemistry (Easton), 2009-07, Vol.48 (27), p.6402-6411

2009

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Identification and structure–activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus

Bioorganic & medicinal chemistry letters, 2023-06, Vol.89, p.129301-129301, Article 129301

2023

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Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs

The Journal of immunology (1950), 2024-02, Vol.212 (4), p.689-701

2024

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Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate

ChemMedChem, 2012-02, Vol.7 (2), p.273-280

2012

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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Circulation (New York, N.Y.), 2024-01, Vol.149 (3), p.227-250

2024

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Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

ACS chemical biology, 2023-04, Vol.18 (4), p.756-771

2023

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GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

The Journal of pharmacology and experimental therapeutics, 2020-11, Vol.375 (2), p.367-357

2020

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Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

Journal of chemical information and modeling, 2020-06, Vol.60 (6), p.2838-2847

2020

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Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.6205-6219

2017

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Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

The American journal of pathology, 2023-12, Vol.193 (12), p.1969-1987

2023

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A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells

ACS chemical biology, 2020-09, Vol.15 (9), p.2338-2345

2020

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Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

European journal of medicinal chemistry, 2023-10, Vol.258, p.115582-115582, Article 115582

2023

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Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism

ACS chemical neuroscience, 2016-02, Vol.7 (2), p.143-148

2016

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The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein

Protein science, 2017-08, Vol.26 (8), p.1595-1608

2017

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Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

ACS infectious diseases, 2017-01, Vol.3 (1), p.89-98

2017

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Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5851-5856

2009

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Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa

A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors

A Synthetic ERR Agonist Alleviates Metabolic Syndrome

Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold

Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804

Identification and structure–activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus

Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs

Discovery and Characterization of Atropisomer PH-797804, a p38 MAP Kinase Inhibitor, as a Clinical Drug Candidate

Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria

Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli

Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney

A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023

Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism

The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein

Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase

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